IRIS
MASSAROTTI, Alberto
 Distribuzione geografica
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Continente #
NA - Nord America 4.153
EU - Europa 3.991
AS - Asia 2.401
SA - Sud America 331
Continente sconosciuto - Info sul continente non disponibili 242
AF - Africa 56
OC - Oceania 2
Totale 11.176
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Nazione #
US - Stati Uniti d'America 3.999
RU - Federazione Russa 810
IT - Italia 792
SG - Singapore 746
IE - Irlanda 661
CN - Cina 550
DE - Germania 471
SE - Svezia 338
VN - Vietnam 321
HK - Hong Kong 300
UA - Ucraina 251
BR - Brasile 238
IN - India 158
FI - Finlandia 148
FR - Francia 148
TR - Turchia 117
GB - Regno Unito 110
EE - Estonia 104
CA - Canada 88
BD - Bangladesh 45
AR - Argentina 40
CZ - Repubblica Ceca 31
PL - Polonia 30
JP - Giappone 24
IR - Iran 21
MX - Messico 20
EC - Ecuador 19
ES - Italia 19
BE - Belgio 18
NL - Olanda 18
ZA - Sudafrica 18
ID - Indonesia 16
IQ - Iraq 16
KR - Corea 13
BJ - Benin 12
TH - Thailandia 12
VE - Venezuela 12
JM - Giamaica 11
AT - Austria 10
LT - Lituania 10
PK - Pakistan 9
CL - Cile 8
MA - Marocco 8
SA - Arabia Saudita 8
AZ - Azerbaigian 7
GT - Guatemala 7
CO - Colombia 6
UZ - Uzbekistan 6
PH - Filippine 5
AE - Emirati Arabi Uniti 4
CR - Costa Rica 4
EU - Europa 4
HN - Honduras 4
IL - Israele 4
KE - Kenya 4
NI - Nicaragua 4
PR - Porto Rico 4
PT - Portogallo 4
SV - El Salvador 4
TW - Taiwan 4
BG - Bulgaria 3
CW - ???statistics.table.value.countryCode.CW??? 3
DK - Danimarca 3
DO - Repubblica Dominicana 3
GR - Grecia 3
JO - Giordania 3
PE - Perù 3
PY - Paraguay 3
TN - Tunisia 3
AU - Australia 2
CI - Costa d'Avorio 2
DZ - Algeria 2
EG - Egitto 2
ET - Etiopia 2
GE - Georgia 2
GP - Guadalupe 2
KY - Cayman, isole 2
LB - Libano 2
MD - Moldavia 2
MY - Malesia 2
OM - Oman 2
AL - Albania 1
AM - Armenia 1
BO - Bolivia 1
CH - Svizzera 1
GA - Gabon 1
HU - Ungheria 1
KZ - Kazakistan 1
LV - Lettonia 1
MR - Mauritania 1
NO - Norvegia 1
NP - Nepal 1
PA - Panama 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
SX - ???statistics.table.value.countryCode.SX??? 1
SY - Repubblica araba siriana 1
TG - Togo 1
UY - Uruguay 1
Totale 10.942
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Città #
Dublin 659
Jacksonville 460
San Jose 415
Hong Kong 297
Dearborn 237
Singapore 236
Ashburn 221
Council Bluffs 194
Beijing 174
Piemonte 154
Ann Arbor 138
Moscow 123
Wilmington 115
Ho Chi Minh City 109
Chandler 108
Los Angeles 107
Columbus 102
Novara 90
Ankara 87
Lawrence 83
Princeton 83
Lauterbourg 77
New York 69
Santa Clara 68
Munich 65
Hanoi 61
San Mateo 58
Phoenix 53
Dallas 47
Vercelli 41
Milan 36
São Paulo 35
Bremen 33
Frankfurt am Main 33
Helsinki 32
Buffalo 31
Orem 31
Toronto 28
Turin 28
Chicago 27
Andover 26
Brno 26
Warsaw 26
Redondo Beach 24
Denver 23
Montreal 22
Turku 22
Rome 21
Tokyo 21
Atlanta 19
Houston 19
Torino 19
Chennai 18
Seattle 18
Tianjin 18
Monmouth Junction 17
Brussels 16
Boston 15
Hefei 15
Johannesburg 15
London 15
Brooklyn 14
Hangzhou 14
Stockholm 14
Haiphong 13
Kocaeli 13
Poplar 13
Cotonou 12
Florence 12
North Bergen 12
Da Nang 11
Guangzhou 11
Norwalk 11
Nuremberg 11
Savignano Sul Panaro 11
Tornaco 11
Kunming 10
Nanjing 10
San Francisco 10
St Louis 10
Cambridge 9
Grafing 9
Kingston 9
Fairfield 8
Formigine 8
Leawood 8
Mexico City 8
Quito 8
Woodbridge 8
Baku 7
Bologna 7
Can Tho 7
Naples 7
Seoul 7
Shanghai 7
Strasbourg 7
Udine 7
Zanjan 7
Ardabil 6
Baghdad 6
Totale 5.833
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Nome #
Structure activity relationship studies on Amb639752: toward the identification of a common pharmacophoric structure for DGKα inhibitors 252
Small molecule inhibitors of West Nile virus 227
Identification of a novel DGKa inhibitor for XLP-1 therapy by virtual screening 206
Identification of a novel NAMPT inhibitor by combinatorial click chemistry and chemical refinement 200
Design, synthesis, and biological evaluation of combretabenzodiazepines: a novel class of anti-tubulin agents 187
Crystal structure of a thermophilic O6-alkylguanine-DNA alkyltransferase-derived self-labeling protein-tag in covalent complex with a fluorescent probe 184
Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity 174
Psychotropic Drugs Show Anticancer Activity by Disrupting Mitochondrial and Lysosomal Function 172
Are 1,4- and 1,5-Disubstituted 1,2,3-Triazoles Good Pharmacophoric Groups? 166
A Concise Synthesis of Pyrazole Analogues of Combretastatin A1 as Potent Antitubulin Agents 165
A multicomponent approach in the discovery of indoleamine 2,3-dioxygenase 1 inhibitors: Synthesis, biological investigation and docking studies 161
Crystal structure of human nicotinic acid phosphoribosyltransferase 160
Multicomponent Reaction of Z-Chlorooximes, Isocyanides, and Hydroxylamines as Hypernucleophilic Traps. A One-Pot Route to Aminodioximes and Their Transformation into 5-Amino-1,2,4-oxadiazoles by Mitsunobu-Beckmann Rearrangement 159
Synthesis, Docking and Biological Evaluation of a Novel Class of Imidazothiazoles as IDO1 Inhibitors 157
Capitolo 23. Istamina e agenti antistaminici 156
Interdomain interactions rearrangements control the reaction steps of a thermostable DNA alkyltransferase 153
Identification of a Potent Phosphoinositide 3-Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs 148
Essential Medicinal Chemistry of Essential Medicines 145
The Guareschi Pyridine Scaffold as a Valuable Platform for the Identification of Selective PI3K Inhibitors 144
Estrogenic analogues synthesized by click chemistry 143
Groebke multicomponent reaction and subsequent nucleophilic aromatic substitution for a convenient synthesis of 3,8-diaminoimidazo[1,2-a]pyrazines as potential kinase inhibitors 142
Medicinal chemistry of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors. 139
Sviluppo di inibitori di DGKα per la terapia della psoriasi all'interno del progetto "Terapie innovative per la psoriasi (TIPSO)" 139
Medicinal Chemistry of Isocyanides 139
Regioselective Suzuki coupling of dihaloheteroaromatic compounds as a rapid strategy to synthesize potent rigid combretastatin analogues 138
Synthesis, biological evaluation and molecular docking of Ugi and Passerini products as novel indoleamine 2,3-dioxygenase 1 inhibitors 138
NOVEL DIACYLGLYCEROL KINASE ALPHA INHIBITORS FOR X-LINKED LYMPHOPROLIFERATIVE DISEASE 1 THERAPY 135
ZINClick 2.0: from a virtual database to smart synthesizable 1,4-disubstituted 1,2,3-triazoles 135
Quinolin-4 (1h) -one derivatives as inhibitors of phosphatidylinositol 3-kinases 132
An in-silico approach aimed to clarify the role of Y181C and K103N HIV-1 reverse transcriptase mutations versus Indole Aryl Sulphones 131
A practical synthesis of 5-aroyl-1-aryltetrazoles using an Ugi-like 4-component reaction followed by a biomimetic transamination 130
The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate 127
De novo computer-aided design of novel antiviral agents 124
Computer-aided identification, design and synthesis of a novel series of compounds with selective antiviral activity against chikungunya virus 123
Acute Myeloid Leukemia: A Key Role of DGKα and DGKζ in Cell Viability 122
Identification of a Compound Inhibiting Both the Enzymatic and Nonenzymatic Functions of Indoleamine 2,3-Dioxygenase 1 122
To each his own: isonitriles for all flavors. Functionalized isocyanides as valuable tools in organic synthesis 122
ChemInform Abstract: Molecular Field Analysis and 3D-Quantitative Structure-Activity Relationship Study (MFA 3D-QSAR) Unveil Novel Features of Bile Acid Recognition at TGR5 122
Discovery of Highly Potent Benzimidazole Derivatives as Indoleamine 2,3-Dioxygenase-1 (IDO1) Inhibitors: From Structure-Based Virtual Screening to in Vivo Pharmacodynamic Activity 122
BDNF Val66Met and clinical response to antipsychotic drugs: A systematic review and meta-analysis 121
Combretastatin analogues: from conformationally restricted compounds to virtual screening 121
Parallel synthesis of “click” chalcones as antitubulin agents 121
The [1,2,4]Triazolo[4,3-a]pyridine as a New Player in the Field of IDO1 Catalytic Holo-Inhibitors 121
ZINClick v.18: Expanding Chemical Space of 1,2,3-Triazoles 118
Replacement of the double bond of antitubulin chalcones with triazoles and tetrazoles: synthesis and biological evaluation 117
In silico-driven multicomponent synthesis of 4,5- and 1,5-disubstituted imidazoles as indoleamine 2,3-dioxygenase inhibitors 116
Broad tuning of the human bitter taste receptor hTAS2R46 to various sesquiterpene lactones, clerodane and labdane diterpenoids, strychnine, and denatonium 116
Are the 1,4 and 1,5-disubstituted-1,2,3-triazoles good pharmacophoric groups? 115
Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis 115
What's in a Name? Drug Nomenclature and Medicinal Chemistry Trends using INN Publications 114
SYNTHESIS AND CHARACTERIZATION OF NEW DGKα INHIBITORS 112
The hitchhiker's guide to the chemical-biological galaxy 112
A nonnatural peptide targeting the A-kinase anchoring function of PI3Kγ for therapeutic cAMP modulation in pulmonary cells 111
Discovering the hidden chemical space of chemistry reactions: from 1,2,3-triazoles nucleus to ZINClick galaxy 110
Solution-Phase Parallel Synthesis of Aryloxyimino Amides via a Novel Multicomponent Reaction among Aromatic (Z)‑Chlorooximes, Isocyanides, and Electron-Deficient Phenols 108
Computational chemistry approaches for discovering new antitubulin compounds 108
Natural Product Fragments Preference for Protein Residues 108
Descriptive structure-separation relationship studies in chiral ligand-exchange chromatography 106
Solution-phase parallel synthesis and biological evaluation of combretatriazoles 105
Synthesis and cytotoxic evaluation of combretafurans, potential scaffolds for dual-action antitumoral agents 104
ZINClick: a database of 16 million of new and patentable 1,4 disubstituted triazoles easily synthetizable 101
ZINClick: A Database of 16 Million Novel, Patentable, and Readily Synthesizable 1,4-Disubstituted Triazoles 100
PI(3,4)P2-mediated cytokinetic abscission prevents early senescence and cataract formation 100
Identification of an inhibitor of Chikungunya virus by virtual screening 99
Arzanol Inhibits Human Dihydroorotate Dehydrogenase and Shows Antiviral Activity 98
Synthesis and biological evaluation of combretatriazoles 98
Sintesi e caratterizzazione di nuovi inibitori di DGKα 97
Structure-property relationship studies in chiral ligand-exchange chromatography 96
ZINClick: a virtual database of 16 million novel, patentable and readily synthesizable 1,4-disubstituted 1,2,3-triazoles 96
2‐(Methyl(phenyl)amino)‐N‐(phenyloxyphenyl)acetamide structural motif representing a framework for selective SIRT2 inhibition 95
Bio-Inspired Dual-Selective BCL-2/c-MYC G-Quadruplex Binders: Design, Synthesis, and Anticancer Activity of Drug-like Imidazo[2,1-i]purine Derivatives 93
The metal face of protein tyrosine phosphatase 1B 91
Rational Discovery of (+) (S) Abscisic Acid as a Potential Antifungal Agent: a Repurposing Approach 91
Photocatalytic Isocyanide-based Multicomponent Domino Cascade Towards the Stereoselective Formation of Iminofurans 91
Therapeutic peptides for the treatment of cystic fibrosis: Challenges and perspectives 90
The adverse outcome pathway (AOP) for chemical binding to tubulin in oocytes leading to aneuploid offspring 87
Haptic-Driven applications to Molecular Modelling: State of the Art and Perspectives 85
Investigation of the Click-Chemical Space for Drug Design Using ZINClick 85
Zinc Ions Modulate Protein Tyrosine Phosphatase 1B activity 84
The tubulin colchicine domain: a molecular modelling perspective 82
Synthesis and biological evaluation of combretatriazoles 82
The taste receptor hTAS2R46 as a general sensor for bitter sesquiterpene lactones 81
Terpenoidi dall’assenzio marino (Artemisia arborescens) e loro interazione con il re-cettore dell’amaro 80
Identification of Novel Antitubulin Agents by using a virtual screening approach based on a 7-point pharmacophore model of the tubulin colchi-site 79
Molecular Field Analysis and 3D-Quantitative Structure-Activity Relationship Studies (MFA 3D-QSAR) of Bile Acids and Fexaramine Derivatives as Agonists of Farnesoid X Receptor (FXR) 78
Development of PROTACs Targeting the Moonlighting Enzyme Nicotinamide Phosphoribosyltransferase (NAMPT) for Breast Cancer Therapy 77
Molecular field analysis and 3D-quantitative structure-activity relationship study (MFA 3D-QSAR) unveil novel features of bile acid recognition at TGR5 74
In search of novel antitubulin agents: synthesis of 1-aryl-5-aroyl tetrazoles by an Ugi 4-CR/hydrogenolysis/transamination reaction 72
Structural biology in antiviral drug discovery 67
Symmetrical 2,7‐disubstituted 9H‐fluoren‐9‐one as a novel and promising scaffold for selective targeting of SIRT2 66
Molecular field analysis and quantitative structure-activity studies (MFA 3D-QSAR) unveil novel features of bile acid recognition at TGR5 receptor 66
Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges 57
In silico approach reveals N-(5-phenoxythiophen-2-yl)-2-(arylthio)acetamides as promising selective SIRT2 inhibitors: the case of structural optimization of virtual screening-derived hits 46
Targeting the NAD+ salvage pathway: Identification of bifunctional NAMPT inhibitors and SIRT1 activators through pharmacophore-based virtual screening 37
Discovery of a Dual IDO1/TDO Inhibitor That Modulates Enzymatic Activity and IDO1/SHP-2 Signaling 35
Totale 11.176
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Categoria #
all - tutte 49.221
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 49.221
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022486 0 0 0 67 26 11 53 20 35 44 84 146
2022/20231.379 95 76 83 26 77 111 61 82 685 9 40 34
2023/2024433 38 25 70 36 71 12 77 20 4 0 23 57
2024/20251.452 37 29 77 25 69 154 122 106 235 182 138 278
2025/20263.849 191 104 283 558 420 270 484 618 261 369 213 78
2026/20271.020 143 304 273 300 0 0 0 0 0 0 0 0
Totale 11.176