IRIS
MASSAROTTI, Alberto
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
EU - Europa 3.918
NA - Nord America 3.609
AS - Asia 2.395
SA - Sud America 326
Continente sconosciuto - Info sul continente non disponibili 237
AF - Africa 55
OC - Oceania 2
Totale 10.542
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 3.503
RU - Federazione Russa 810
IT - Italia 756
SG - Singapore 746
IE - Irlanda 661
CN - Cina 546
DE - Germania 469
SE - Svezia 337
VN - Vietnam 321
HK - Hong Kong 299
UA - Ucraina 251
BR - Brasile 237
IN - India 158
FI - Finlandia 148
FR - Francia 148
TR - Turchia 117
EE - Estonia 99
GB - Regno Unito 84
CA - Canada 67
BD - Bangladesh 45
AR - Argentina 38
CZ - Repubblica Ceca 31
PL - Polonia 29
JP - Giappone 24
IR - Iran 21
ES - Italia 19
MX - Messico 19
BE - Belgio 18
EC - Ecuador 18
NL - Olanda 17
ZA - Sudafrica 17
ID - Indonesia 16
IQ - Iraq 16
KR - Corea 13
BJ - Benin 12
TH - Thailandia 12
VE - Venezuela 11
AT - Austria 10
LT - Lituania 10
PK - Pakistan 9
CL - Cile 8
MA - Marocco 8
AZ - Azerbaigian 7
SA - Arabia Saudita 7
CO - Colombia 6
UZ - Uzbekistan 6
JM - Giamaica 5
PH - Filippine 5
AE - Emirati Arabi Uniti 4
EU - Europa 4
IL - Israele 4
KE - Kenya 4
PT - Portogallo 4
TW - Taiwan 4
BG - Bulgaria 3
DO - Repubblica Dominicana 3
GR - Grecia 3
HN - Honduras 3
JO - Giordania 3
PE - Perù 3
PY - Paraguay 3
TN - Tunisia 3
AU - Australia 2
CI - Costa d'Avorio 2
DK - Danimarca 2
DZ - Algeria 2
EG - Egitto 2
ET - Etiopia 2
GE - Georgia 2
GT - Guatemala 2
LB - Libano 2
MD - Moldavia 2
MY - Malesia 2
OM - Oman 2
PR - Porto Rico 2
AL - Albania 1
AM - Armenia 1
BO - Bolivia 1
CH - Svizzera 1
CR - Costa Rica 1
GA - Gabon 1
GP - Guadalupe 1
HU - Ungheria 1
KY - Cayman, isole 1
KZ - Kazakistan 1
LV - Lettonia 1
MR - Mauritania 1
NI - Nicaragua 1
NO - Norvegia 1
NP - Nepal 1
PA - Panama 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
SY - Repubblica araba siriana 1
TG - Togo 1
UY - Uruguay 1
Totale 10.309
Salva come PNG Salva come JPEG
Città #
Dublin 659
Jacksonville 457
San Jose 328
Hong Kong 296
Dearborn 237
Singapore 236
Ashburn 203
Beijing 174
Council Bluffs 170
Piemonte 154
Ann Arbor 138
Moscow 123
Wilmington 115
Ho Chi Minh City 109
Chandler 108
Columbus 101
Los Angeles 99
Novara 90
Ankara 87
Lawrence 83
Princeton 83
Lauterbourg 77
Munich 65
New York 63
Hanoi 61
San Mateo 58
Santa Clara 56
Vercelli 41
Dallas 40
São Paulo 35
Bremen 33
Frankfurt am Main 33
Helsinki 32
Orem 31
Milan 30
Buffalo 29
Andover 26
Brno 26
Turin 26
Warsaw 25
Redondo Beach 24
Toronto 24
Turku 22
Tokyo 21
Montreal 20
Phoenix 20
Chicago 19
Torino 19
Chennai 18
Tianjin 18
Denver 17
Houston 17
Monmouth Junction 17
Brussels 16
Hefei 15
Johannesburg 15
Rome 15
Atlanta 14
Hangzhou 14
London 14
Boston 13
Haiphong 13
Kocaeli 13
Poplar 13
Seattle 13
Stockholm 13
Cotonou 12
Brooklyn 11
Da Nang 11
Guangzhou 11
Norwalk 11
Nuremberg 11
Savignano Sul Panaro 11
Tornaco 11
Florence 10
Kunming 10
Nanjing 10
Cambridge 9
Grafing 9
St Louis 9
Formigine 8
Leawood 8
Mexico City 8
San Francisco 8
Woodbridge 8
Baku 7
Bologna 7
Can Tho 7
Fairfield 7
Quito 7
Seoul 7
Strasbourg 7
Udine 7
Zanjan 7
Ardabil 6
Baghdad 6
Biên Hòa 6
Dhaka 6
Hillsboro 6
Imola 6
Totale 5.559
Salva come PNG Salva come JPEG
Nome #
Structure activity relationship studies on Amb639752: toward the identification of a common pharmacophoric structure for DGKα inhibitors 245
Small molecule inhibitors of West Nile virus 225
Identification of a novel DGKa inhibitor for XLP-1 therapy by virtual screening 196
Identification of a novel NAMPT inhibitor by combinatorial click chemistry and chemical refinement 192
Design, synthesis, and biological evaluation of combretabenzodiazepines: a novel class of anti-tubulin agents 181
Crystal structure of a thermophilic O6-alkylguanine-DNA alkyltransferase-derived self-labeling protein-tag in covalent complex with a fluorescent probe 175
Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity 168
A Concise Synthesis of Pyrazole Analogues of Combretastatin A1 as Potent Antitubulin Agents 162
Psychotropic Drugs Show Anticancer Activity by Disrupting Mitochondrial and Lysosomal Function 162
Are 1,4- and 1,5-Disubstituted 1,2,3-Triazoles Good Pharmacophoric Groups? 157
A multicomponent approach in the discovery of indoleamine 2,3-dioxygenase 1 inhibitors: Synthesis, biological investigation and docking studies 155
Capitolo 23. Istamina e agenti antistaminici 152
Crystal structure of human nicotinic acid phosphoribosyltransferase 150
Synthesis, Docking and Biological Evaluation of a Novel Class of Imidazothiazoles as IDO1 Inhibitors 148
Multicomponent Reaction of Z-Chlorooximes, Isocyanides, and Hydroxylamines as Hypernucleophilic Traps. A One-Pot Route to Aminodioximes and Their Transformation into 5-Amino-1,2,4-oxadiazoles by Mitsunobu-Beckmann Rearrangement 146
Interdomain interactions rearrangements control the reaction steps of a thermostable DNA alkyltransferase 142
Identification of a Potent Phosphoinositide 3-Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs 140
The Guareschi Pyridine Scaffold as a Valuable Platform for the Identification of Selective PI3K Inhibitors 139
Estrogenic analogues synthesized by click chemistry 136
Groebke multicomponent reaction and subsequent nucleophilic aromatic substitution for a convenient synthesis of 3,8-diaminoimidazo[1,2-a]pyrazines as potential kinase inhibitors 136
Synthesis, biological evaluation and molecular docking of Ugi and Passerini products as novel indoleamine 2,3-dioxygenase 1 inhibitors 135
Essential Medicinal Chemistry of Essential Medicines 135
Medicinal chemistry of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors. 132
Regioselective Suzuki coupling of dihaloheteroaromatic compounds as a rapid strategy to synthesize potent rigid combretastatin analogues 131
Sviluppo di inibitori di DGKα per la terapia della psoriasi all'interno del progetto "Terapie innovative per la psoriasi (TIPSO)" 131
ZINClick 2.0: from a virtual database to smart synthesizable 1,4-disubstituted 1,2,3-triazoles 131
Medicinal Chemistry of Isocyanides 131
NOVEL DIACYLGLYCEROL KINASE ALPHA INHIBITORS FOR X-LINKED LYMPHOPROLIFERATIVE DISEASE 1 THERAPY 129
Quinolin-4 (1h) -one derivatives as inhibitors of phosphatidylinositol 3-kinases 127
An in-silico approach aimed to clarify the role of Y181C and K103N HIV-1 reverse transcriptase mutations versus Indole Aryl Sulphones 124
A practical synthesis of 5-aroyl-1-aryltetrazoles using an Ugi-like 4-component reaction followed by a biomimetic transamination 122
De novo computer-aided design of novel antiviral agents 121
The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate 120
To each his own: isonitriles for all flavors. Functionalized isocyanides as valuable tools in organic synthesis 119
Computer-aided identification, design and synthesis of a novel series of compounds with selective antiviral activity against chikungunya virus 117
Combretastatin analogues: from conformationally restricted compounds to virtual screening 116
Parallel synthesis of “click” chalcones as antitubulin agents 115
In silico-driven multicomponent synthesis of 4,5- and 1,5-disubstituted imidazoles as indoleamine 2,3-dioxygenase inhibitors 114
ChemInform Abstract: Molecular Field Analysis and 3D-Quantitative Structure-Activity Relationship Study (MFA 3D-QSAR) Unveil Novel Features of Bile Acid Recognition at TGR5 114
The [1,2,4]Triazolo[4,3-a]pyridine as a New Player in the Field of IDO1 Catalytic Holo-Inhibitors 114
Identification of a Compound Inhibiting Both the Enzymatic and Nonenzymatic Functions of Indoleamine 2,3-Dioxygenase 1 113
ZINClick v.18: Expanding Chemical Space of 1,2,3-Triazoles 113
Replacement of the double bond of antitubulin chalcones with triazoles and tetrazoles: synthesis and biological evaluation 112
Are the 1,4 and 1,5-disubstituted-1,2,3-triazoles good pharmacophoric groups? 111
SYNTHESIS AND CHARACTERIZATION OF NEW DGKα INHIBITORS 110
Discovery of Highly Potent Benzimidazole Derivatives as Indoleamine 2,3-Dioxygenase-1 (IDO1) Inhibitors: From Structure-Based Virtual Screening to in Vivo Pharmacodynamic Activity 110
What's in a Name? Drug Nomenclature and Medicinal Chemistry Trends using INN Publications 109
Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis 109
BDNF Val66Met and clinical response to antipsychotic drugs: A systematic review and meta-analysis 108
Broad tuning of the human bitter taste receptor hTAS2R46 to various sesquiterpene lactones, clerodane and labdane diterpenoids, strychnine, and denatonium 108
Discovering the hidden chemical space of chemistry reactions: from 1,2,3-triazoles nucleus to ZINClick galaxy 107
The hitchhiker's guide to the chemical-biological galaxy 106
Solution-Phase Parallel Synthesis of Aryloxyimino Amides via a Novel Multicomponent Reaction among Aromatic (Z)‑Chlorooximes, Isocyanides, and Electron-Deficient Phenols 105
Descriptive structure-separation relationship studies in chiral ligand-exchange chromatography 104
Computational chemistry approaches for discovering new antitubulin compounds 104
Natural Product Fragments Preference for Protein Residues 103
Solution-phase parallel synthesis and biological evaluation of combretatriazoles 101
Acute Myeloid Leukemia: A Key Role of DGKα and DGKζ in Cell Viability 100
Synthesis and cytotoxic evaluation of combretafurans, potential scaffolds for dual-action antitumoral agents 100
ZINClick: A Database of 16 Million Novel, Patentable, and Readily Synthesizable 1,4-Disubstituted Triazoles 98
ZINClick: a database of 16 million of new and patentable 1,4 disubstituted triazoles easily synthetizable 98
Identification of an inhibitor of Chikungunya virus by virtual screening 96
Sintesi e caratterizzazione di nuovi inibitori di DGKα 96
Structure-property relationship studies in chiral ligand-exchange chromatography 94
Synthesis and biological evaluation of combretatriazoles 94
A nonnatural peptide targeting the A-kinase anchoring function of PI3Kγ for therapeutic cAMP modulation in pulmonary cells 93
PI(3,4)P2-mediated cytokinetic abscission prevents early senescence and cataract formation 93
ZINClick: a virtual database of 16 million novel, patentable and readily synthesizable 1,4-disubstituted 1,2,3-triazoles 91
Photocatalytic Isocyanide-based Multicomponent Domino Cascade Towards the Stereoselective Formation of Iminofurans 89
2‐(Methyl(phenyl)amino)‐N‐(phenyloxyphenyl)acetamide structural motif representing a framework for selective SIRT2 inhibition 88
Bio-Inspired Dual-Selective BCL-2/c-MYC G-Quadruplex Binders: Design, Synthesis, and Anticancer Activity of Drug-like Imidazo[2,1-i]purine Derivatives 85
Arzanol Inhibits Human Dihydroorotate Dehydrogenase and Shows Antiviral Activity 83
The adverse outcome pathway (AOP) for chemical binding to tubulin in oocytes leading to aneuploid offspring 83
Rational Discovery of (+) (S) Abscisic Acid as a Potential Antifungal Agent: a Repurposing Approach 83
The metal face of protein tyrosine phosphatase 1B 82
Haptic-Driven applications to Molecular Modelling: State of the Art and Perspectives 82
Synthesis and biological evaluation of combretatriazoles 80
Investigation of the Click-Chemical Space for Drug Design Using ZINClick 80
Terpenoidi dall’assenzio marino (Artemisia arborescens) e loro interazione con il re-cettore dell’amaro 79
The taste receptor hTAS2R46 as a general sensor for bitter sesquiterpene lactones 79
Therapeutic peptides for the treatment of cystic fibrosis: Challenges and perspectives 79
The tubulin colchicine domain: a molecular modelling perspective 78
Zinc Ions Modulate Protein Tyrosine Phosphatase 1B activity 78
Molecular Field Analysis and 3D-Quantitative Structure-Activity Relationship Studies (MFA 3D-QSAR) of Bile Acids and Fexaramine Derivatives as Agonists of Farnesoid X Receptor (FXR) 77
Identification of Novel Antitubulin Agents by using a virtual screening approach based on a 7-point pharmacophore model of the tubulin colchi-site 77
Molecular field analysis and 3D-quantitative structure-activity relationship study (MFA 3D-QSAR) unveil novel features of bile acid recognition at TGR5 70
In search of novel antitubulin agents: synthesis of 1-aryl-5-aroyl tetrazoles by an Ugi 4-CR/hydrogenolysis/transamination reaction 70
Molecular field analysis and quantitative structure-activity studies (MFA 3D-QSAR) unveil novel features of bile acid recognition at TGR5 receptor 65
Structural biology in antiviral drug discovery 64
Development of PROTACs Targeting the Moonlighting Enzyme Nicotinamide Phosphoribosyltransferase (NAMPT) for Breast Cancer Therapy 59
Symmetrical 2,7‐disubstituted 9H‐fluoren‐9‐one as a novel and promising scaffold for selective targeting of SIRT2 59
Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges 50
In silico approach reveals N-(5-phenoxythiophen-2-yl)-2-(arylthio)acetamides as promising selective SIRT2 inhibitors: the case of structural optimization of virtual screening-derived hits 41
Targeting the NAD+ salvage pathway: Identification of bifunctional NAMPT inhibitors and SIRT1 activators through pharmacophore-based virtual screening 11
Totale 10.542
Salva come PNG Salva come JPEG
Categoria #
all - tutte 45.961
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 45.961
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022556 0 17 53 67 26 11 53 20 35 44 84 146
2022/20231.379 95 76 83 26 77 111 61 82 685 9 40 34
2023/2024433 38 25 70 36 71 12 77 20 4 0 23 57
2024/20251.452 37 29 77 25 69 154 122 106 235 182 138 278
2025/20263.849 191 104 283 558 420 270 484 618 261 369 213 78
2026/2027386 143 243 0 0 0 0 0 0 0 0 0 0
Totale 10.542