IRIS
MASSAROTTI, Alberto
 Distribuzione geografica
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Continente #
EU - Europa 2.268
NA - Nord America 1.854
AS - Asia 450
Continente sconosciuto - Info sul continente non disponibili 4
SA - Sud America 3
Totale 4.579
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Nazione #
US - Stati Uniti d'America 1.834
IE - Irlanda 660
IT - Italia 510
DE - Germania 331
SE - Svezia 323
UA - Ucraina 234
CN - Cina 148
IN - India 115
FI - Finlandia 105
TR - Turchia 88
HK - Hong Kong 70
GB - Regno Unito 27
FR - Francia 26
IR - Iran 21
CA - Canada 19
CZ - Repubblica Ceca 17
BE - Belgio 12
RU - Federazione Russa 9
NL - Olanda 5
EU - Europa 4
GR - Grecia 3
VN - Vietnam 3
DK - Danimarca 2
AT - Austria 1
BR - Brasile 1
CL - Cile 1
HN - Honduras 1
IQ - Iraq 1
JP - Giappone 1
KR - Corea 1
LT - Lituania 1
MD - Moldavia 1
PE - Perù 1
PH - Filippine 1
PT - Portogallo 1
TH - Thailandia 1
Totale 4.579
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Città #
Dublin 658
Jacksonville 457
Dearborn 237
Piemonte 154
Ann Arbor 138
Wilmington 113
Chandler 108
Lawrence 83
Princeton 83
Ankara 70
Hong Kong 70
Beijing 62
San Mateo 58
Ashburn 40
Bremen 33
Andover 26
Milan 23
Torino 19
Monmouth Junction 17
Brno 16
Toronto 15
Hefei 14
Helsinki 14
Turin 14
Kocaeli 13
Brussels 12
Norwalk 11
Novara 11
Savignano Sul Panaro 11
Kunming 10
Vercelli 10
Grafing 9
Houston 9
Nanjing 9
Dallas 8
Formigine 8
Leawood 8
Woodbridge 8
Fairfield 7
Strasbourg 7
Udine 7
Zanjan 7
Ardabil 6
Imola 6
Nanchang 6
Noicattaro 6
Seattle 6
Zola Predosa 6
Bologna 5
Cambridge 5
Cerano 5
Grignasco 5
Berlin 4
Chengdu 4
Kecioeren 4
Legnano 4
Marigliano 4
Modena 4
Shenyang 4
Wuhan 4
Albano Laziale 3
Athens 3
Des Moines 3
Forio 3
Fuzhou 3
Guangzhou 3
Hebei 3
Huzhou 3
Jinan 3
Montesarchio 3
Pavia 3
Rome 3
Sacramento 3
San Giuliano Milanese 3
Wachtberg 3
Zhengzhou 3
Boardman 2
Cameriano 2
Ceppaloni 2
Curcuris 2
Dong Ket 2
Florence 2
Gorla Maggiore 2
Gunzenhausen 2
Hangzhou 2
Lyngby 2
Occimiano 2
Odalengo Grande 2
Redmond 2
Sesto Fiorentino 2
Vergiate 2
Wenzhou 2
Aachen 1
Absecon 1
Augusta 1
Aveiro 1
Baghdad 1
Baotou 1
Borgomanero 1
Brugherio 1
Totale 2.863
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Nome #
Structure activity relationship studies on Amb639752: toward the identification of a common pharmacophoric structure for DGKα inhibitors 137
Identification of a novel DGKa inhibitor for XLP-1 therapy by virtual screening 116
Identification of a novel NAMPT inhibitor by combinatorial click chemistry and chemical refinement 111
Design, synthesis, and biological evaluation of combretabenzodiazepines: a novel class of anti-tubulin agents 94
Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity 94
ZINClick 2.0: from a virtual database to smart synthesizable 1,4-disubstituted 1,2,3-triazoles 87
Capitolo 23. Istamina e agenti antistaminici 84
Psychotropic Drugs Show Anticancer Activity by Disrupting Mitochondrial and Lysosomal Function 83
Discovery of Highly Potent Benzimidazole Derivatives as Indoleamine 2,3-Dioxygenase-1 (IDO1) Inhibitors: From Structure-Based Virtual Screening to in Vivo Pharmacodynamic Activity 81
Medicinal chemistry of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors. 79
Synthesis, biological evaluation and molecular docking of Ugi and Passerini products as novel indoleamine 2,3-dioxygenase 1 inhibitors 79
Crystal structure of a thermophilic O6-alkylguanine-DNA alkyltransferase-derived self-labeling protein-tag in covalent complex with a fluorescent probe 79
Crystal structure of human nicotinic acid phosphoribosyltransferase 78
A Concise Synthesis of Pyrazole Analogues of Combretastatin A1 as Potent Antitubulin Agents 77
NOVEL DIACYLGLYCEROL KINASE ALPHA INHIBITORS FOR X-LINKED LYMPHOPROLIFERATIVE DISEASE 1 THERAPY 76
The Guareschi Pyridine Scaffold as a Valuable Platform for the Identification of Selective PI3K Inhibitors 76
Interdomain interactions rearrangements control the reaction steps of a thermostable DNA alkyltransferase 76
Identification of a Potent Phosphoinositide 3-Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs 75
In silico-driven multicomponent synthesis of 4,5- and 1,5-disubstituted imidazoles as indoleamine 2,3-dioxygenase inhibitors 74
Sviluppo di inibitori di DGKα per la terapia della psoriasi all'interno del progetto "Terapie innovative per la psoriasi (TIPSO)" 74
Quinolin-4 (1h) -one derivatives as inhibitors of phosphatidylinositol 3-kinases 70
A multicomponent approach in the discovery of indoleamine 2,3-dioxygenase 1 inhibitors: Synthesis, biological investigation and docking studies 70
Synthesis, Docking and Biological Evaluation of a Novel Class of Imidazothiazoles as IDO1 Inhibitors 70
Groebke multicomponent reaction and subsequent nucleophilic aromatic substitution for a convenient synthesis of 3,8-diaminoimidazo[1,2-a]pyrazines as potential kinase inhibitors 69
Are 1,4- and 1,5-Disubstituted 1,2,3-Triazoles Good Pharmacophoric Groups? 69
Regioselective Suzuki coupling of dihaloheteroaromatic compounds as a rapid strategy to synthesize potent rigid combretastatin analogues 68
SYNTHESIS AND CHARACTERIZATION OF NEW DGKα INHIBITORS 67
The Essential Medicinal Chemistry of Essential Medicines 66
Replacement of the double bond of antitubulin chalcones with triazoles and tetrazoles: synthesis and biological evaluation 63
Estrogenic analogues synthesized by click chemistry 62
To each his own: isonitriles for all flavors. Functionalized isocyanides as valuable tools in organic synthesis 62
Solution-Phase Parallel Synthesis of Aryloxyimino Amides via a Novel Multicomponent Reaction among Aromatic (Z)‑Chlorooximes, Isocyanides, and Electron-Deficient Phenols 61
Multicomponent Reaction of Z-Chlorooximes, Isocyanides, and Hydroxylamines as Hypernucleophilic Traps. A One-Pot Route to Aminodioximes and Their Transformation into 5-Amino-1,2,4-oxadiazoles by Mitsunobu-Beckmann Rearrangement 59
Computer-aided identification, design and synthesis of a novel series of compounds with selective antiviral activity against chikungunya virus 56
Descriptive structure-separation relationship studies in chiral ligand-exchange chromatography 56
BDNF Val66Met and clinical response to antipsychotic drugs: A systematic review and meta-analysis 56
Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis 55
Solution-phase parallel synthesis and biological evaluation of combretatriazoles 54
Sintesi e caratterizzazione di nuovi inibitori di DGKα 54
An in-silico approach aimed to clarify the role of Y181C and K103N HIV-1 reverse transcriptase mutations versus Indole Aryl Sulphones 53
Discovering the hidden chemical space of chemistry reactions: from 1,2,3-triazoles nucleus to ZINClick galaxy 53
Synthesis and cytotoxic evaluation of combretafurans, potential scaffolds for dual-action antitumoral agents 52
ZINClick: A Database of 16 Million Novel, Patentable, and Readily Synthesizable 1,4-Disubstituted Triazoles 52
The adverse outcome pathway (AOP) for chemical binding to tubulin in oocytes leading to aneuploid offspring 52
Are the 1,4 and 1,5-disubstituted-1,2,3-triazoles good pharmacophoric groups? 51
Parallel synthesis of “click” chalcones as antitubulin agents 50
ZINClick v.18: Expanding Chemical Space of 1,2,3-Triazoles 49
De novo computer-aided design of novel antiviral agents 47
Combretastatin analogues: from conformationally restricted compounds to virtual screening 47
Broad tuning of the human bitter taste receptor hTAS2R46 to various sesquiterpene lactones, clerodane and labdane diterpenoids, strychnine, and denatonium 47
Identification of Novel Antitubulin Agents by using a virtual screening approach based on a 7-point pharmacophore model of the tubulin colchi-site 47
ChemInform Abstract: Molecular Field Analysis and 3D-Quantitative Structure-Activity Relationship Study (MFA 3D-QSAR) Unveil Novel Features of Bile Acid Recognition at TGR5 47
The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate 47
Identification of an inhibitor of Chikungunya virus by virtual screening 46
The hitchhiker's guide to the chemical-biological galaxy 46
A practical synthesis of 5-aroyl-1-aryltetrazoles using an Ugi-like 4-component reaction followed by a biomimetic transamination 45
Computational chemistry approaches for discovering new antitubulin compounds 45
Zinc Ions Modulate Protein Tyrosine Phosphatase 1B activity 45
Terpenoidi dall’assenzio marino (Artemisia arborescens) e loro interazione con il re-cettore dell’amaro 44
Molecular Field Analysis and 3D-Quantitative Structure-Activity Relationship Studies (MFA 3D-QSAR) of Bile Acids and Fexaramine Derivatives as Agonists of Farnesoid X Receptor (FXR) 43
The tubulin colchicine domain: a molecular modelling perspective 42
Synthesis and biological evaluation of combretatriazoles 42
ZINClick: a database of 16 million of new and patentable 1,4 disubstituted triazoles easily synthetizable 42
Haptic-Driven applications to Molecular Modelling: State of the Art and Perspectives 41
Natural Product Fragments Preference for Protein Residues 41
Small molecule inhibitors of West Nile virus 40
In search of novel antitubulin agents: synthesis of 1-aryl-5-aroyl tetrazoles by an Ugi 4-CR/hydrogenolysis/transamination reaction 40
Medicinal Chemistry of Isocyanides 40
Molecular field analysis and 3D-quantitative structure-activity relationship study (MFA 3D-QSAR) unveil novel features of bile acid recognition at TGR5 39
Photocatalytic Isocyanide-based Multicomponent Domino Cascade Towards the Stereoselective Formation of Iminofurans 39
Structural biology in antiviral drug discovery 38
Rational Discovery of (+) (S) Abscisic Acid as a Potential Antifungal Agent: a Repurposing Approach 38
What's in a Name? Drug Nomenclature and Medicinal Chemistry Trends using INN Publications 37
ZINClick: a virtual database of 16 million novel, patentable and readily synthesizable 1,4-disubstituted 1,2,3-triazoles 37
The taste receptor hTAS2R46 as a general sensor for bitter sesquiterpene lactones 37
Synthesis and biological evaluation of combretatriazoles 37
The metal face of protein tyrosine phosphatase 1B 36
Structure-property relationship studies in chiral ligand-exchange chromatography 34
The [1,2,4]Triazolo[4,3-a]pyridine as a New Player in the Field of IDO1 Catalytic Holo-Inhibitors 34
Molecular field analysis and quantitative structure-activity studies (MFA 3D-QSAR) unveil novel features of bile acid recognition at TGR5 receptor 30
Investigation of the Click-Chemical Space for Drug Design Using ZINClick 30
PI(3,4)P2-mediated cytokinetic abscission prevents early senescence and cataract formation 25
Therapeutic peptides for the treatment of cystic fibrosis: Challenges and perspectives 24
Bio-Inspired Dual-Selective BCL-2/c-MYC G-Quadruplex Binders: Design, Synthesis, and Anticancer Activity of Drug-like Imidazo[2,1-i]purine Derivatives 5
In silico approach reveals N-(5-phenoxythiophen-2-yl)-2-(arylthio)acetamides as promising selective SIRT2 inhibitors: the case of structural optimization of virtual screening-derived hits 3
Totale 4.776
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Categoria #
all - tutte 19.711
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 19.711
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/201921 0 0 0 0 0 0 0 0 0 0 13 8
2019/2020986 5 5 76 9 155 139 206 41 90 148 97 15
2020/2021700 87 2 82 13 99 45 100 21 112 49 81 9
2021/2022612 56 17 53 67 26 11 53 20 35 44 84 146
2022/20231.379 95 76 83 26 77 111 61 82 685 9 40 34
2023/2024354 38 25 70 36 71 12 77 20 4 0 1 0
Totale 4.776