IRIS
MASSAROTTI, Alberto
 Distribuzione geografica
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Continente #
EU - Europa 3.899
NA - Nord America 3.263
AS - Asia 2.360
SA - Sud America 318
AF - Africa 55
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 2
Totale 9.901
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Nazione #
US - Stati Uniti d'America 3.170
RU - Federazione Russa 810
IT - Italia 744
SG - Singapore 740
IE - Irlanda 661
CN - Cina 538
DE - Germania 469
SE - Svezia 337
VN - Vietnam 320
HK - Hong Kong 289
UA - Ucraina 251
BR - Brasile 233
IN - India 157
FI - Finlandia 148
FR - Francia 146
TR - Turchia 117
EE - Estonia 99
GB - Regno Unito 84
CA - Canada 61
BD - Bangladesh 37
AR - Argentina 36
CZ - Repubblica Ceca 31
PL - Polonia 29
JP - Giappone 24
IR - Iran 21
MX - Messico 19
BE - Belgio 18
EC - Ecuador 18
ES - Italia 18
NL - Olanda 17
ZA - Sudafrica 17
ID - Indonesia 16
IQ - Iraq 16
KR - Corea 13
BJ - Benin 12
TH - Thailandia 11
VE - Venezuela 11
AT - Austria 10
LT - Lituania 10
PK - Pakistan 9
CL - Cile 8
MA - Marocco 8
AZ - Azerbaigian 7
SA - Arabia Saudita 7
UZ - Uzbekistan 6
PH - Filippine 5
AE - Emirati Arabi Uniti 4
CO - Colombia 4
EU - Europa 4
IL - Israele 4
KE - Kenya 4
TW - Taiwan 4
DO - Repubblica Dominicana 3
GR - Grecia 3
JM - Giamaica 3
JO - Giordania 3
PE - Perù 3
PY - Paraguay 3
TN - Tunisia 3
AU - Australia 2
CI - Costa d'Avorio 2
DK - Danimarca 2
DZ - Algeria 2
EG - Egitto 2
ET - Etiopia 2
GE - Georgia 2
LB - Libano 2
MD - Moldavia 2
MY - Malesia 2
OM - Oman 2
PR - Porto Rico 2
PT - Portogallo 2
AL - Albania 1
AM - Armenia 1
BG - Bulgaria 1
BO - Bolivia 1
CH - Svizzera 1
GA - Gabon 1
GT - Guatemala 1
HN - Honduras 1
HU - Ungheria 1
KY - Cayman, isole 1
KZ - Kazakistan 1
LV - Lettonia 1
MR - Mauritania 1
NI - Nicaragua 1
NO - Norvegia 1
NP - Nepal 1
PA - Panama 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
SY - Repubblica araba siriana 1
TG - Togo 1
UY - Uruguay 1
Totale 9.901
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Città #
Dublin 659
Jacksonville 457
San Jose 326
Hong Kong 286
Dearborn 237
Singapore 233
Ashburn 191
Beijing 171
Piemonte 154
Ann Arbor 138
Moscow 123
Wilmington 115
Chandler 108
Ho Chi Minh City 108
Los Angeles 95
Novara 90
Ankara 87
Lawrence 83
Princeton 83
Lauterbourg 77
Council Bluffs 66
Munich 65
New York 63
Hanoi 61
San Mateo 58
Santa Clara 42
Vercelli 41
Dallas 39
São Paulo 34
Bremen 33
Frankfurt am Main 33
Helsinki 32
Orem 31
Milan 30
Buffalo 29
Andover 26
Brno 26
Turin 26
Warsaw 25
Redondo Beach 24
Toronto 23
Turku 22
Tokyo 21
Montreal 19
Torino 19
Chennai 18
Chicago 18
Tianjin 18
Denver 17
Houston 17
Monmouth Junction 17
Brussels 16
Hefei 15
Johannesburg 15
Phoenix 15
Atlanta 14
Hangzhou 14
London 14
Haiphong 13
Kocaeli 13
Poplar 13
Seattle 13
Stockholm 13
Cotonou 12
Rome 12
Da Nang 11
Guangzhou 11
Norwalk 11
Nuremberg 11
Savignano Sul Panaro 11
Tornaco 11
Brooklyn 10
Columbus 10
Florence 10
Kunming 10
Nanjing 10
Boston 9
Cambridge 9
Grafing 9
Formigine 8
Leawood 8
Mexico City 8
San Francisco 8
Woodbridge 8
Baku 7
Bologna 7
Can Tho 7
Fairfield 7
Quito 7
Seoul 7
St Louis 7
Strasbourg 7
Udine 7
Zanjan 7
Ardabil 6
Baghdad 6
Biên Hòa 6
Dhaka 6
Hillsboro 6
Imola 6
Totale 5.295
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Nome #
Structure activity relationship studies on Amb639752: toward the identification of a common pharmacophoric structure for DGKα inhibitors 238
Small molecule inhibitors of West Nile virus 223
Identification of a novel DGKa inhibitor for XLP-1 therapy by virtual screening 192
Identification of a novel NAMPT inhibitor by combinatorial click chemistry and chemical refinement 189
Design, synthesis, and biological evaluation of combretabenzodiazepines: a novel class of anti-tubulin agents 178
Crystal structure of a thermophilic O6-alkylguanine-DNA alkyltransferase-derived self-labeling protein-tag in covalent complex with a fluorescent probe 168
Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity 166
A Concise Synthesis of Pyrazole Analogues of Combretastatin A1 as Potent Antitubulin Agents 160
Psychotropic Drugs Show Anticancer Activity by Disrupting Mitochondrial and Lysosomal Function 156
Are 1,4- and 1,5-Disubstituted 1,2,3-Triazoles Good Pharmacophoric Groups? 155
A multicomponent approach in the discovery of indoleamine 2,3-dioxygenase 1 inhibitors: Synthesis, biological investigation and docking studies 153
Capitolo 23. Istamina e agenti antistaminici 150
Crystal structure of human nicotinic acid phosphoribosyltransferase 148
Synthesis, Docking and Biological Evaluation of a Novel Class of Imidazothiazoles as IDO1 Inhibitors 142
Multicomponent Reaction of Z-Chlorooximes, Isocyanides, and Hydroxylamines as Hypernucleophilic Traps. A One-Pot Route to Aminodioximes and Their Transformation into 5-Amino-1,2,4-oxadiazoles by Mitsunobu-Beckmann Rearrangement 138
Interdomain interactions rearrangements control the reaction steps of a thermostable DNA alkyltransferase 137
Identification of a Potent Phosphoinositide 3-Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs 135
Estrogenic analogues synthesized by click chemistry 133
The Guareschi Pyridine Scaffold as a Valuable Platform for the Identification of Selective PI3K Inhibitors 133
Synthesis, biological evaluation and molecular docking of Ugi and Passerini products as novel indoleamine 2,3-dioxygenase 1 inhibitors 132
Essential Medicinal Chemistry of Essential Medicines 131
Medicinal chemistry of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors. 130
Groebke multicomponent reaction and subsequent nucleophilic aromatic substitution for a convenient synthesis of 3,8-diaminoimidazo[1,2-a]pyrazines as potential kinase inhibitors 130
Sviluppo di inibitori di DGKα per la terapia della psoriasi all'interno del progetto "Terapie innovative per la psoriasi (TIPSO)" 128
Regioselective Suzuki coupling of dihaloheteroaromatic compounds as a rapid strategy to synthesize potent rigid combretastatin analogues 127
NOVEL DIACYLGLYCEROL KINASE ALPHA INHIBITORS FOR X-LINKED LYMPHOPROLIFERATIVE DISEASE 1 THERAPY 127
Medicinal Chemistry of Isocyanides 127
ZINClick 2.0: from a virtual database to smart synthesizable 1,4-disubstituted 1,2,3-triazoles 126
An in-silico approach aimed to clarify the role of Y181C and K103N HIV-1 reverse transcriptase mutations versus Indole Aryl Sulphones 121
Quinolin-4 (1h) -one derivatives as inhibitors of phosphatidylinositol 3-kinases 120
A practical synthesis of 5-aroyl-1-aryltetrazoles using an Ugi-like 4-component reaction followed by a biomimetic transamination 118
To each his own: isonitriles for all flavors. Functionalized isocyanides as valuable tools in organic synthesis 116
The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate 116
Computer-aided identification, design and synthesis of a novel series of compounds with selective antiviral activity against chikungunya virus 115
De novo computer-aided design of novel antiviral agents 115
Combretastatin analogues: from conformationally restricted compounds to virtual screening 114
Parallel synthesis of “click” chalcones as antitubulin agents 113
In silico-driven multicomponent synthesis of 4,5- and 1,5-disubstituted imidazoles as indoleamine 2,3-dioxygenase inhibitors 112
ChemInform Abstract: Molecular Field Analysis and 3D-Quantitative Structure-Activity Relationship Study (MFA 3D-QSAR) Unveil Novel Features of Bile Acid Recognition at TGR5 111
Identification of a Compound Inhibiting Both the Enzymatic and Nonenzymatic Functions of Indoleamine 2,3-Dioxygenase 1 109
Replacement of the double bond of antitubulin chalcones with triazoles and tetrazoles: synthesis and biological evaluation 109
ZINClick v.18: Expanding Chemical Space of 1,2,3-Triazoles 109
Are the 1,4 and 1,5-disubstituted-1,2,3-triazoles good pharmacophoric groups? 108
The [1,2,4]Triazolo[4,3-a]pyridine as a New Player in the Field of IDO1 Catalytic Holo-Inhibitors 107
BDNF Val66Met and clinical response to antipsychotic drugs: A systematic review and meta-analysis 106
SYNTHESIS AND CHARACTERIZATION OF NEW DGKα INHIBITORS 106
Broad tuning of the human bitter taste receptor hTAS2R46 to various sesquiterpene lactones, clerodane and labdane diterpenoids, strychnine, and denatonium 105
What's in a Name? Drug Nomenclature and Medicinal Chemistry Trends using INN Publications 103
Solution-Phase Parallel Synthesis of Aryloxyimino Amides via a Novel Multicomponent Reaction among Aromatic (Z)‑Chlorooximes, Isocyanides, and Electron-Deficient Phenols 102
Discovering the hidden chemical space of chemistry reactions: from 1,2,3-triazoles nucleus to ZINClick galaxy 102
Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis 102
Descriptive structure-separation relationship studies in chiral ligand-exchange chromatography 101
Computational chemistry approaches for discovering new antitubulin compounds 101
Discovery of Highly Potent Benzimidazole Derivatives as Indoleamine 2,3-Dioxygenase-1 (IDO1) Inhibitors: From Structure-Based Virtual Screening to in Vivo Pharmacodynamic Activity 101
The hitchhiker's guide to the chemical-biological galaxy 100
Natural Product Fragments Preference for Protein Residues 98
Solution-phase parallel synthesis and biological evaluation of combretatriazoles 97
Synthesis and cytotoxic evaluation of combretafurans, potential scaffolds for dual-action antitumoral agents 96
ZINClick: A Database of 16 Million Novel, Patentable, and Readily Synthesizable 1,4-Disubstituted Triazoles 94
Identification of an inhibitor of Chikungunya virus by virtual screening 94
Sintesi e caratterizzazione di nuovi inibitori di DGKα 92
Acute Myeloid Leukemia: A Key Role of DGKα and DGKζ in Cell Viability 90
Synthesis and biological evaluation of combretatriazoles 90
PI(3,4)P2-mediated cytokinetic abscission prevents early senescence and cataract formation 90
A nonnatural peptide targeting the A-kinase anchoring function of PI3Kγ for therapeutic cAMP modulation in pulmonary cells 89
ZINClick: a virtual database of 16 million novel, patentable and readily synthesizable 1,4-disubstituted 1,2,3-triazoles 89
ZINClick: a database of 16 million of new and patentable 1,4 disubstituted triazoles easily synthetizable 89
Structure-property relationship studies in chiral ligand-exchange chromatography 88
2‐(Methyl(phenyl)amino)‐N‐(phenyloxyphenyl)acetamide structural motif representing a framework for selective SIRT2 inhibition 84
Photocatalytic Isocyanide-based Multicomponent Domino Cascade Towards the Stereoselective Formation of Iminofurans 83
The adverse outcome pathway (AOP) for chemical binding to tubulin in oocytes leading to aneuploid offspring 80
Bio-Inspired Dual-Selective BCL-2/c-MYC G-Quadruplex Binders: Design, Synthesis, and Anticancer Activity of Drug-like Imidazo[2,1-i]purine Derivatives 80
Haptic-Driven applications to Molecular Modelling: State of the Art and Perspectives 79
Rational Discovery of (+) (S) Abscisic Acid as a Potential Antifungal Agent: a Repurposing Approach 77
The tubulin colchicine domain: a molecular modelling perspective 76
Synthesis and biological evaluation of combretatriazoles 76
Terpenoidi dall’assenzio marino (Artemisia arborescens) e loro interazione con il re-cettore dell’amaro 76
Zinc Ions Modulate Protein Tyrosine Phosphatase 1B activity 76
The metal face of protein tyrosine phosphatase 1B 75
Therapeutic peptides for the treatment of cystic fibrosis: Challenges and perspectives 75
Identification of Novel Antitubulin Agents by using a virtual screening approach based on a 7-point pharmacophore model of the tubulin colchi-site 75
Molecular Field Analysis and 3D-Quantitative Structure-Activity Relationship Studies (MFA 3D-QSAR) of Bile Acids and Fexaramine Derivatives as Agonists of Farnesoid X Receptor (FXR) 74
The taste receptor hTAS2R46 as a general sensor for bitter sesquiterpene lactones 74
Investigation of the Click-Chemical Space for Drug Design Using ZINClick 73
Arzanol Inhibits Human Dihydroorotate Dehydrogenase and Shows Antiviral Activity 69
In search of novel antitubulin agents: synthesis of 1-aryl-5-aroyl tetrazoles by an Ugi 4-CR/hydrogenolysis/transamination reaction 68
Molecular field analysis and 3D-quantitative structure-activity relationship study (MFA 3D-QSAR) unveil novel features of bile acid recognition at TGR5 66
Molecular field analysis and quantitative structure-activity studies (MFA 3D-QSAR) unveil novel features of bile acid recognition at TGR5 receptor 62
Structural biology in antiviral drug discovery 62
Symmetrical 2,7‐disubstituted 9H‐fluoren‐9‐one as a novel and promising scaffold for selective targeting of SIRT2 56
Development of PROTACs Targeting the Moonlighting Enzyme Nicotinamide Phosphoribosyltransferase (NAMPT) for Breast Cancer Therapy 51
Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges 43
In silico approach reveals N-(5-phenoxythiophen-2-yl)-2-(arylthio)acetamides as promising selective SIRT2 inhibitors: the case of structural optimization of virtual screening-derived hits 33
Totale 10.133
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Categoria #
all - tutte 43.641
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 43.641
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20219 0 0 0 0 0 0 0 0 0 0 0 9
2021/2022612 56 17 53 67 26 11 53 20 35 44 84 146
2022/20231.379 95 76 83 26 77 111 61 82 685 9 40 34
2023/2024433 38 25 70 36 71 12 77 20 4 0 23 57
2024/20251.452 37 29 77 25 69 154 122 106 235 182 138 278
2025/20263.826 191 104 283 558 420 270 484 618 261 369 213 55
Totale 10.133