IRIS
MASSAROTTI, Alberto
 Distribuzione geografica
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Continente #
EU - Europa 3.894
NA - Nord America 3.042
AS - Asia 2.317
SA - Sud America 321
AF - Africa 54
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 2
Totale 9.634
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Nazione #
US - Stati Uniti d'America 2.956
RU - Federazione Russa 816
IT - Italia 729
SG - Singapore 715
IE - Irlanda 661
CN - Cina 524
DE - Germania 472
SE - Svezia 337
VN - Vietnam 325
HK - Hong Kong 288
UA - Ucraina 251
BR - Brasile 233
IN - India 157
FI - Finlandia 149
FR - Francia 149
TR - Turchia 117
EE - Estonia 101
GB - Regno Unito 85
CA - Canada 55
AR - Argentina 38
BD - Bangladesh 29
PL - Polonia 29
CZ - Repubblica Ceca 28
JP - Giappone 23
IR - Iran 21
MX - Messico 20
EC - Ecuador 19
BE - Belgio 18
ES - Italia 18
ID - Indonesia 17
ZA - Sudafrica 17
IQ - Iraq 16
NL - Olanda 15
BJ - Benin 12
KR - Corea 11
TH - Thailandia 11
VE - Venezuela 11
AT - Austria 10
LT - Lituania 10
PK - Pakistan 10
CL - Cile 8
MA - Marocco 8
AZ - Azerbaigian 7
SA - Arabia Saudita 7
UZ - Uzbekistan 7
PH - Filippine 5
AE - Emirati Arabi Uniti 4
CO - Colombia 4
EU - Europa 4
IL - Israele 4
KE - Kenya 4
TW - Taiwan 4
DO - Repubblica Dominicana 3
GR - Grecia 3
JO - Giordania 3
PE - Perù 3
PY - Paraguay 3
TN - Tunisia 3
AU - Australia 2
CI - Costa d'Avorio 2
DK - Danimarca 2
DZ - Algeria 2
ET - Etiopia 2
GE - Georgia 2
JM - Giamaica 2
LB - Libano 2
MY - Malesia 2
OM - Oman 2
PR - Porto Rico 2
PT - Portogallo 2
AL - Albania 1
AM - Armenia 1
BG - Bulgaria 1
BO - Bolivia 1
CH - Svizzera 1
EG - Egitto 1
GA - Gabon 1
GT - Guatemala 1
HN - Honduras 1
HU - Ungheria 1
KZ - Kazakistan 1
LV - Lettonia 1
MD - Moldavia 1
MR - Mauritania 1
NO - Norvegia 1
NP - Nepal 1
PA - Panama 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
SV - El Salvador 1
SY - Repubblica araba siriana 1
TG - Togo 1
UY - Uruguay 1
Totale 9.634
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Città #
Dublin 659
Jacksonville 457
Hong Kong 285
San Jose 260
Dearborn 237
Singapore 235
Ashburn 186
Beijing 174
Piemonte 154
Ann Arbor 138
Moscow 124
Wilmington 114
Ho Chi Minh City 110
Chandler 108
Novara 96
Ankara 87
Los Angeles 86
Lawrence 83
Princeton 83
Lauterbourg 77
Munich 68
Hanoi 63
San Mateo 58
New York 55
Vercelli 42
Dallas 35
São Paulo 34
Bremen 33
Frankfurt am Main 33
Helsinki 32
Orem 32
Buffalo 30
Milan 30
Santa Clara 29
Andover 26
Brno 26
Turin 25
Warsaw 25
Redondo Beach 24
Turku 23
Tokyo 21
Toronto 21
Torino 19
Chennai 18
Chicago 18
Montreal 18
Monmouth Junction 17
Tianjin 17
Brussels 16
Denver 16
Houston 16
Johannesburg 15
Council Bluffs 14
Hefei 14
London 14
Phoenix 14
Haiphong 13
Kocaeli 13
Poplar 13
Stockholm 13
Atlanta 12
Cotonou 12
Seattle 12
Da Nang 11
Guangzhou 11
Hangzhou 11
Norwalk 11
Nuremberg 11
Savignano Sul Panaro 11
Florence 10
Kunming 10
Nanjing 10
Rome 10
Boston 9
Brooklyn 9
Grafing 9
Formigine 8
Leawood 8
Mexico City 8
Woodbridge 8
Baku 7
Cambridge 7
Can Tho 7
Fairfield 7
Hillsboro 7
Quito 7
San Francisco 7
Seoul 7
Strasbourg 7
Udine 7
Zanjan 7
Ardabil 6
Baghdad 6
Biên Hòa 6
Dhaka 6
Imola 6
Nanchang 6
Noicattaro 6
Reston 6
Tashkent 6
Totale 5.128
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Nome #
Structure activity relationship studies on Amb639752: toward the identification of a common pharmacophoric structure for DGKα inhibitors 229
Small molecule inhibitors of West Nile virus 221
Identification of a novel DGKa inhibitor for XLP-1 therapy by virtual screening 189
Identification of a novel NAMPT inhibitor by combinatorial click chemistry and chemical refinement 187
Design, synthesis, and biological evaluation of combretabenzodiazepines: a novel class of anti-tubulin agents 171
Crystal structure of a thermophilic O6-alkylguanine-DNA alkyltransferase-derived self-labeling protein-tag in covalent complex with a fluorescent probe 163
Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity 161
A Concise Synthesis of Pyrazole Analogues of Combretastatin A1 as Potent Antitubulin Agents 158
Psychotropic Drugs Show Anticancer Activity by Disrupting Mitochondrial and Lysosomal Function 152
Are 1,4- and 1,5-Disubstituted 1,2,3-Triazoles Good Pharmacophoric Groups? 151
A multicomponent approach in the discovery of indoleamine 2,3-dioxygenase 1 inhibitors: Synthesis, biological investigation and docking studies 151
Crystal structure of human nicotinic acid phosphoribosyltransferase 145
Capitolo 23. Istamina e agenti antistaminici 141
Synthesis, Docking and Biological Evaluation of a Novel Class of Imidazothiazoles as IDO1 Inhibitors 138
Interdomain interactions rearrangements control the reaction steps of a thermostable DNA alkyltransferase 134
Identification of a Potent Phosphoinositide 3-Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs 131
Medicinal chemistry of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors. 129
Multicomponent Reaction of Z-Chlorooximes, Isocyanides, and Hydroxylamines as Hypernucleophilic Traps. A One-Pot Route to Aminodioximes and Their Transformation into 5-Amino-1,2,4-oxadiazoles by Mitsunobu-Beckmann Rearrangement 128
Estrogenic analogues synthesized by click chemistry 127
Synthesis, biological evaluation and molecular docking of Ugi and Passerini products as novel indoleamine 2,3-dioxygenase 1 inhibitors 127
Sviluppo di inibitori di DGKα per la terapia della psoriasi all'interno del progetto "Terapie innovative per la psoriasi (TIPSO)" 126
Regioselective Suzuki coupling of dihaloheteroaromatic compounds as a rapid strategy to synthesize potent rigid combretastatin analogues 125
Groebke multicomponent reaction and subsequent nucleophilic aromatic substitution for a convenient synthesis of 3,8-diaminoimidazo[1,2-a]pyrazines as potential kinase inhibitors 125
ZINClick 2.0: from a virtual database to smart synthesizable 1,4-disubstituted 1,2,3-triazoles 125
NOVEL DIACYLGLYCEROL KINASE ALPHA INHIBITORS FOR X-LINKED LYMPHOPROLIFERATIVE DISEASE 1 THERAPY 123
An in-silico approach aimed to clarify the role of Y181C and K103N HIV-1 reverse transcriptase mutations versus Indole Aryl Sulphones 121
The Guareschi Pyridine Scaffold as a Valuable Platform for the Identification of Selective PI3K Inhibitors 121
Essential Medicinal Chemistry of Essential Medicines 119
Quinolin-4 (1h) -one derivatives as inhibitors of phosphatidylinositol 3-kinases 118
A practical synthesis of 5-aroyl-1-aryltetrazoles using an Ugi-like 4-component reaction followed by a biomimetic transamination 116
To each his own: isonitriles for all flavors. Functionalized isocyanides as valuable tools in organic synthesis 114
Medicinal Chemistry of Isocyanides 114
The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate 113
Combretastatin analogues: from conformationally restricted compounds to virtual screening 111
Parallel synthesis of “click” chalcones as antitubulin agents 111
Computer-aided identification, design and synthesis of a novel series of compounds with selective antiviral activity against chikungunya virus 110
De novo computer-aided design of novel antiviral agents 110
In silico-driven multicomponent synthesis of 4,5- and 1,5-disubstituted imidazoles as indoleamine 2,3-dioxygenase inhibitors 109
ChemInform Abstract: Molecular Field Analysis and 3D-Quantitative Structure-Activity Relationship Study (MFA 3D-QSAR) Unveil Novel Features of Bile Acid Recognition at TGR5 108
Are the 1,4 and 1,5-disubstituted-1,2,3-triazoles good pharmacophoric groups? 107
Broad tuning of the human bitter taste receptor hTAS2R46 to various sesquiterpene lactones, clerodane and labdane diterpenoids, strychnine, and denatonium 105
ZINClick v.18: Expanding Chemical Space of 1,2,3-Triazoles 105
Replacement of the double bond of antitubulin chalcones with triazoles and tetrazoles: synthesis and biological evaluation 104
BDNF Val66Met and clinical response to antipsychotic drugs: A systematic review and meta-analysis 104
SYNTHESIS AND CHARACTERIZATION OF NEW DGKα INHIBITORS 101
Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis 101
Solution-Phase Parallel Synthesis of Aryloxyimino Amides via a Novel Multicomponent Reaction among Aromatic (Z)‑Chlorooximes, Isocyanides, and Electron-Deficient Phenols 100
Discovering the hidden chemical space of chemistry reactions: from 1,2,3-triazoles nucleus to ZINClick galaxy 100
null 100
Descriptive structure-separation relationship studies in chiral ligand-exchange chromatography 99
Computational chemistry approaches for discovering new antitubulin compounds 99
The hitchhiker's guide to the chemical-biological galaxy 99
Identification of a Compound Inhibiting Both the Enzymatic and Nonenzymatic Functions of Indoleamine 2,3-Dioxygenase 1 98
Natural Product Fragments Preference for Protein Residues 98
Solution-phase parallel synthesis and biological evaluation of combretatriazoles 96
The [1,2,4]Triazolo[4,3-a]pyridine as a New Player in the Field of IDO1 Catalytic Holo-Inhibitors 95
Synthesis and cytotoxic evaluation of combretafurans, potential scaffolds for dual-action antitumoral agents 94
ZINClick: A Database of 16 Million Novel, Patentable, and Readily Synthesizable 1,4-Disubstituted Triazoles 93
Sintesi e caratterizzazione di nuovi inibitori di DGKα 91
Identification of an inhibitor of Chikungunya virus by virtual screening 90
Synthesis and biological evaluation of combretatriazoles 90
What's in a Name? Drug Nomenclature and Medicinal Chemistry Trends using INN Publications 89
ZINClick: a virtual database of 16 million novel, patentable and readily synthesizable 1,4-disubstituted 1,2,3-triazoles 88
ZINClick: a database of 16 million of new and patentable 1,4 disubstituted triazoles easily synthetizable 88
PI(3,4)P2-mediated cytokinetic abscission prevents early senescence and cataract formation 87
Structure-property relationship studies in chiral ligand-exchange chromatography 86
A nonnatural peptide targeting the A-kinase anchoring function of PI3Kγ for therapeutic cAMP modulation in pulmonary cells 85
2‐(Methyl(phenyl)amino)‐N‐(phenyloxyphenyl)acetamide structural motif representing a framework for selective SIRT2 inhibition 80
Photocatalytic Isocyanide-based Multicomponent Domino Cascade Towards the Stereoselective Formation of Iminofurans 79
Bio-Inspired Dual-Selective BCL-2/c-MYC G-Quadruplex Binders: Design, Synthesis, and Anticancer Activity of Drug-like Imidazo[2,1-i]purine Derivatives 79
The adverse outcome pathway (AOP) for chemical binding to tubulin in oocytes leading to aneuploid offspring 78
Haptic-Driven applications to Molecular Modelling: State of the Art and Perspectives 77
Discovery of Highly Potent Benzimidazole Derivatives as Indoleamine 2,3-Dioxygenase-1 (IDO1) Inhibitors: From Structure-Based Virtual Screening to in Vivo Pharmacodynamic Activity 75
Rational Discovery of (+) (S) Abscisic Acid as a Potential Antifungal Agent: a Repurposing Approach 75
The tubulin colchicine domain: a molecular modelling perspective 74
Terpenoidi dall’assenzio marino (Artemisia arborescens) e loro interazione con il re-cettore dell’amaro 74
Therapeutic peptides for the treatment of cystic fibrosis: Challenges and perspectives 74
Zinc Ions Modulate Protein Tyrosine Phosphatase 1B activity 74
Acute Myeloid Leukemia: A Key Role of DGKα and DGKζ in Cell Viability 73
Synthesis and biological evaluation of combretatriazoles 73
The metal face of protein tyrosine phosphatase 1B 73
Molecular Field Analysis and 3D-Quantitative Structure-Activity Relationship Studies (MFA 3D-QSAR) of Bile Acids and Fexaramine Derivatives as Agonists of Farnesoid X Receptor (FXR) 72
Identification of Novel Antitubulin Agents by using a virtual screening approach based on a 7-point pharmacophore model of the tubulin colchi-site 72
Investigation of the Click-Chemical Space for Drug Design Using ZINClick 71
The taste receptor hTAS2R46 as a general sensor for bitter sesquiterpene lactones 70
Arzanol Inhibits Human Dihydroorotate Dehydrogenase and Shows Antiviral Activity 66
Molecular field analysis and 3D-quantitative structure-activity relationship study (MFA 3D-QSAR) unveil novel features of bile acid recognition at TGR5 65
In search of novel antitubulin agents: synthesis of 1-aryl-5-aroyl tetrazoles by an Ugi 4-CR/hydrogenolysis/transamination reaction 65
Molecular field analysis and quantitative structure-activity studies (MFA 3D-QSAR) unveil novel features of bile acid recognition at TGR5 receptor 61
Structural biology in antiviral drug discovery 60
Symmetrical 2,7‐disubstituted 9H‐fluoren‐9‐one as a novel and promising scaffold for selective targeting of SIRT2 55
Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges 38
Development of PROTACs Targeting the Moonlighting Enzyme Nicotinamide Phosphoribosyltransferase (NAMPT) for Breast Cancer Therapy 38
In silico approach reveals N-(5-phenoxythiophen-2-yl)-2-(arylthio)acetamides as promising selective SIRT2 inhibitors: the case of structural optimization of virtual screening-derived hits 30
Totale 9.865
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Categoria #
all - tutte 41.683
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 41.683
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021139 0 0 0 0 0 0 0 0 0 49 81 9
2021/2022612 56 17 53 67 26 11 53 20 35 44 84 146
2022/20231.379 95 76 83 26 77 111 61 82 685 9 40 34
2023/2024433 38 25 70 36 71 12 77 20 4 0 23 57
2024/20251.470 37 29 77 25 69 154 122 114 239 184 138 282
2025/20263.540 197 107 289 562 428 273 494 625 266 299 0 0
Totale 9.865