MASSAROTTI, Alberto
MASSAROTTI, Alberto
Dipartimento di Scienze del Farmaco
2‐(Methyl(phenyl)amino)‐N‐(phenyloxyphenyl)acetamide structural motif representing a framework for selective SIRT2 inhibition
2024-01-01 Kaya, Selen Gozde; Eren, Gokcen; Massarotti, Alberto; Bakar‐ates, Filiz; Ozkan, Erva; Gozelle, Mahmut; Ozkan, Yesim
A Concise Synthesis of Pyrazole Analogues of Combretastatin A1 as Potent Antitubulin Agents
2013-01-01 Zaninetti, Roberta; Cortese, Sv; Aprile, Silvio; Massarotti, Alberto; Canonico, Pier Luigi; Sorba, Giovanni; Grosa, Giorgio; Genazzani, Armando; Pirali, Tracey
A multicomponent approach in the discovery of indoleamine 2,3-dioxygenase 1 inhibitors: Synthesis, biological investigation and docking studies
2018-01-01 Griglio, Alessia; Torre, Enza; Serafini, Marta; Bianchi, Alice; Schmid, Roberta; CODA ZABETTA, Giulia; Massarotti, Alberto; Sorba, Giovanni; Pirali, Tracey; Fallarini, Silvia
A nonnatural peptide targeting the A-kinase anchoring function of PI3Kγ for therapeutic cAMP modulation in pulmonary cells
2024-01-01 Della Sala, Angela; Tasca, Laura; Butnarasu, Cosmin; Sala, Valentina; Prono, Giulia; Murabito, Alessandra; Garbero, Olga Valentina; Millo, Enrico; Terranova, Leonardo; Blasi, Francesco; Gramegna, Andrea; Aliberti, Stefano; Massarotti, Alberto; Visentin, Sonja; Hirsch, Emilio; Ghigo, Alessandra
A practical synthesis of 5-aroyl-1-aryltetrazoles using an Ugi-like 4-component reaction followed by a biomimetic transamination
2010-01-01 Giustiniano, M; Pirali, Tracey; Massarotti, Alberto; Biletta, B; Novellino, E; Campiglia, P; Sorba, Giovanni; Tron, Gian Cesare
An in-silico approach aimed to clarify the role of Y181C and K103N HIV-1 reverse transcriptase mutations versus Indole Aryl Sulphones
2016-01-01 Massarotti, Alberto; Coluccia, Antonio
Are 1,4- and 1,5-Disubstituted 1,2,3-Triazoles Good Pharmacophoric Groups?
2014-01-01 Massarotti, Alberto; Aprile, Silvio; Mercalli, Valentina; DEL GROSSO, Erika; Grosa, Giorgio; Sorba, Giovanni; Tron, Gian Cesare
Are the 1,4 and 1,5-disubstituted-1,2,3-triazoles good pharmacophoric groups?
2012-01-01 Massarotti, Alberto; Genazzani, A. A.; Tron, Gian Cesare
BDNF Val66Met and clinical response to antipsychotic drugs: A systematic review and meta-analysis
2016-01-01 Cargnin, Sarah; Massarotti, Alberto; Terrazzino, Salvatore
Bio-Inspired Dual-Selective BCL-2/c-MYC G-Quadruplex Binders: Design, Synthesis, and Anticancer Activity of Drug-like Imidazo[2,1-i]purine Derivatives
2020-01-01 Pelliccia, Sveva; Amato, Jussara; Capasso, Domenica; Di Gaetano, Sonia; Massarotti, Alberto; Piccolo, Marialuisa; Irace, Carlo; Tron, Gian Cesare; Pagano, Bruno; Randazzo, Antonio; Novellino, Ettore; Giustiniano, Mariateresa
Broad tuning of the human bitter taste receptor hTAS2R46 to various sesquiterpene lactones, clerodane and labdane diterpenoids, strychnine, and denatonium
2007-01-01 Brockhoff, A; Behrens, M; Massarotti, Alberto; Appendino, Giovanni Battista; Meyerhof, W.
Capitolo 23. Istamina e agenti antistaminici
2014-01-01 Sorba, Giovanni; Massarotti, Alberto
ChemInform Abstract: Molecular Field Analysis and 3D-Quantitative Structure-Activity Relationship Study (MFA 3D-QSAR) Unveil Novel Features of Bile Acid Recognition at TGR5
2008-01-01 Macchiarulo, Antonio; Gioiello, Antimo; Thomas, Charles; Massarotti, Alberto; Nuti, Roberto; Rosatelli, Emiliano; Sabbatini, Paola; Schoonjans, Kristina; Auwerx, Johan; Pellicciari, Roberto
Combretastatin analogues: from conformationally restricted compounds to virtual screening
2008-01-01 Massarotti, Alberto
Computational chemistry approaches for discovering new antitubulin compounds
2009-01-01 Massarotti, Alberto
Computer-aided identification, design and synthesis of a novel series of compounds with selective antiviral activity against chikungunya virus
2013-01-01 Bassetto, M; De Burghgraeve, T; Delang, L; Massarotti, Alberto; Coluccia, A; Zonta, N; Gatti, V; Colombano, Giampiero; Sorba, Giovanni; Silvestri, R; Tron, Gian Cesare; Neyts, J; Leyssen, P; Brancale, A.
Crystal structure of a thermophilic O6-alkylguanine-DNA alkyltransferase-derived self-labeling protein-tag in covalent complex with a fluorescent probe
2018-01-01 Rossi, Franca; Morrone, Castrese; Massarotti, Alberto; Ferraris, Davide Maria; Valenti, Anna; Perugino, Giuseppe; Miggiano, Riccardo
Crystal structure of human nicotinic acid phosphoribosyltransferase
2015-01-01 Marletta, ADA SERENA; Massarotti, Alberto; Orsomando, Giuseppe; Magni, Giulio; Rizzi, Menico; Garavaglia, Silvia
De novo computer-aided design of novel antiviral agents
2012-01-01 Massarotti, Alberto; Coluccia, A; Sorba, Giovanni; Silvestri, R; Brancale, A.
Descriptive structure-separation relationship studies in chiral ligand-exchange chromatography
2008-01-01 Natalini, B; Macchiarulo, A; Sardella, R; Massarotti, Alberto; Pellicciari, R.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 2‐(Methyl(phenyl)amino)‐N‐(phenyloxyphenyl)acetamide structural motif representing a framework for selective SIRT2 inhibition | 1-gen-2024 | Kaya, Selen Gozde; Eren, Gokcen; Massarotti, Alberto; Bakar‐ates, Filiz; Ozkan, Erva; Gozelle, Mahmut; Ozkan, Yesim | |
| A Concise Synthesis of Pyrazole Analogues of Combretastatin A1 as Potent Antitubulin Agents | 1-gen-2013 | Zaninetti, Roberta; Cortese, Sv; Aprile, Silvio; Massarotti, Alberto; Canonico, Pier Luigi; Sorba, Giovanni; Grosa, Giorgio; Genazzani, Armando; Pirali, Tracey | |
| A multicomponent approach in the discovery of indoleamine 2,3-dioxygenase 1 inhibitors: Synthesis, biological investigation and docking studies | 1-gen-2018 | Griglio, Alessia; Torre, Enza; Serafini, Marta; Bianchi, Alice; Schmid, Roberta; CODA ZABETTA, Giulia; Massarotti, Alberto; Sorba, Giovanni; Pirali, Tracey; Fallarini, Silvia | |
| A nonnatural peptide targeting the A-kinase anchoring function of PI3Kγ for therapeutic cAMP modulation in pulmonary cells | 1-gen-2024 | Della Sala, Angela; Tasca, Laura; Butnarasu, Cosmin; Sala, Valentina; Prono, Giulia; Murabito, Alessandra; Garbero, Olga Valentina; Millo, Enrico; Terranova, Leonardo; Blasi, Francesco; Gramegna, Andrea; Aliberti, Stefano; Massarotti, Alberto; Visentin, Sonja; Hirsch, Emilio; Ghigo, Alessandra | |
| A practical synthesis of 5-aroyl-1-aryltetrazoles using an Ugi-like 4-component reaction followed by a biomimetic transamination | 1-gen-2010 | Giustiniano, M; Pirali, Tracey; Massarotti, Alberto; Biletta, B; Novellino, E; Campiglia, P; Sorba, Giovanni; Tron, Gian Cesare | |
| An in-silico approach aimed to clarify the role of Y181C and K103N HIV-1 reverse transcriptase mutations versus Indole Aryl Sulphones | 1-gen-2016 | Massarotti, Alberto; Coluccia, Antonio | |
| Are 1,4- and 1,5-Disubstituted 1,2,3-Triazoles Good Pharmacophoric Groups? | 1-gen-2014 | Massarotti, Alberto; Aprile, Silvio; Mercalli, Valentina; DEL GROSSO, Erika; Grosa, Giorgio; Sorba, Giovanni; Tron, Gian Cesare | |
| Are the 1,4 and 1,5-disubstituted-1,2,3-triazoles good pharmacophoric groups? | 1-gen-2012 | Massarotti, Alberto; Genazzani, A. A.; Tron, Gian Cesare | |
| BDNF Val66Met and clinical response to antipsychotic drugs: A systematic review and meta-analysis | 1-gen-2016 | Cargnin, Sarah; Massarotti, Alberto; Terrazzino, Salvatore | |
| Bio-Inspired Dual-Selective BCL-2/c-MYC G-Quadruplex Binders: Design, Synthesis, and Anticancer Activity of Drug-like Imidazo[2,1-i]purine Derivatives | 1-gen-2020 | Pelliccia, Sveva; Amato, Jussara; Capasso, Domenica; Di Gaetano, Sonia; Massarotti, Alberto; Piccolo, Marialuisa; Irace, Carlo; Tron, Gian Cesare; Pagano, Bruno; Randazzo, Antonio; Novellino, Ettore; Giustiniano, Mariateresa | |
| Broad tuning of the human bitter taste receptor hTAS2R46 to various sesquiterpene lactones, clerodane and labdane diterpenoids, strychnine, and denatonium | 1-gen-2007 | Brockhoff, A; Behrens, M; Massarotti, Alberto; Appendino, Giovanni Battista; Meyerhof, W. | |
| Capitolo 23. Istamina e agenti antistaminici | 1-gen-2014 | Sorba, Giovanni; Massarotti, Alberto | |
| ChemInform Abstract: Molecular Field Analysis and 3D-Quantitative Structure-Activity Relationship Study (MFA 3D-QSAR) Unveil Novel Features of Bile Acid Recognition at TGR5 | 1-gen-2008 | Macchiarulo, Antonio; Gioiello, Antimo; Thomas, Charles; Massarotti, Alberto; Nuti, Roberto; Rosatelli, Emiliano; Sabbatini, Paola; Schoonjans, Kristina; Auwerx, Johan; Pellicciari, Roberto | |
| Combretastatin analogues: from conformationally restricted compounds to virtual screening | 1-gen-2008 | Massarotti, Alberto | |
| Computational chemistry approaches for discovering new antitubulin compounds | 1-gen-2009 | Massarotti, Alberto | |
| Computer-aided identification, design and synthesis of a novel series of compounds with selective antiviral activity against chikungunya virus | 1-gen-2013 | Bassetto, M; De Burghgraeve, T; Delang, L; Massarotti, Alberto; Coluccia, A; Zonta, N; Gatti, V; Colombano, Giampiero; Sorba, Giovanni; Silvestri, R; Tron, Gian Cesare; Neyts, J; Leyssen, P; Brancale, A. | |
| Crystal structure of a thermophilic O6-alkylguanine-DNA alkyltransferase-derived self-labeling protein-tag in covalent complex with a fluorescent probe | 1-gen-2018 | Rossi, Franca; Morrone, Castrese; Massarotti, Alberto; Ferraris, Davide Maria; Valenti, Anna; Perugino, Giuseppe; Miggiano, Riccardo | |
| Crystal structure of human nicotinic acid phosphoribosyltransferase | 1-gen-2015 | Marletta, ADA SERENA; Massarotti, Alberto; Orsomando, Giuseppe; Magni, Giulio; Rizzi, Menico; Garavaglia, Silvia | |
| De novo computer-aided design of novel antiviral agents | 1-gen-2012 | Massarotti, Alberto; Coluccia, A; Sorba, Giovanni; Silvestri, R; Brancale, A. | |
| Descriptive structure-separation relationship studies in chiral ligand-exchange chromatography | 1-gen-2008 | Natalini, B; Macchiarulo, A; Sardella, R; Massarotti, Alberto; Pellicciari, R. |