IRIS
GROSA, Giorgio
 Distribuzione geografica
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Continente #
EU - Europa 3.345
NA - Nord America 3.148
AS - Asia 1.548
SA - Sud America 245
AF - Africa 35
Continente sconosciuto - Info sul continente non disponibili 9
OC - Oceania 1
Totale 8.331
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Nazione #
US - Stati Uniti d'America 3.093
IE - Irlanda 762
SE - Svezia 535
DE - Germania 512
IT - Italia 489
SG - Singapore 482
CN - Cina 400
UA - Ucraina 356
HK - Hong Kong 283
FI - Finlandia 216
BR - Brasile 190
RU - Federazione Russa 188
VN - Vietnam 112
GB - Regno Unito 103
IN - India 98
FR - Francia 49
KR - Corea 47
CA - Canada 32
TR - Turchia 32
BE - Belgio 31
IR - Iran 29
EE - Estonia 25
AR - Argentina 22
CZ - Repubblica Ceca 18
MX - Messico 17
JP - Giappone 15
ES - Italia 14
PL - Polonia 13
BJ - Benin 10
LT - Lituania 10
BD - Bangladesh 9
EU - Europa 9
ID - Indonesia 9
ZA - Sudafrica 9
EC - Ecuador 8
IQ - Iraq 8
CL - Cile 6
NL - Olanda 6
PK - Pakistan 5
UZ - Uzbekistan 5
AT - Austria 4
BG - Bulgaria 4
CH - Svizzera 4
CO - Colombia 4
EG - Egitto 4
MA - Marocco 4
PE - Perù 4
PY - Paraguay 4
VE - Venezuela 4
GR - Grecia 3
SA - Arabia Saudita 3
AE - Emirati Arabi Uniti 2
BO - Bolivia 2
CI - Costa d'Avorio 2
DK - Danimarca 2
JO - Giordania 2
TN - Tunisia 2
AO - Angola 1
CG - Congo 1
DM - Dominica 1
DZ - Algeria 1
GT - Guatemala 1
HN - Honduras 1
IL - Israele 1
KE - Kenya 1
KW - Kuwait 1
LK - Sri Lanka 1
LV - Lettonia 1
MY - Malesia 1
NZ - Nuova Zelanda 1
PA - Panama 1
PH - Filippine 1
PR - Porto Rico 1
TM - Turkmenistan 1
TT - Trinidad e Tobago 1
TW - Taiwan 1
UY - Uruguay 1
Totale 8.331
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Città #
Dublin 762
Jacksonville 588
Hong Kong 283
Dearborn 280
Chandler 261
Beijing 219
Singapore 168
Wilmington 154
Ann Arbor 147
Ashburn 146
Piemonte 128
Lawrence 100
Princeton 100
Los Angeles 90
Moscow 84
San Mateo 81
Andover 68
Munich 66
Buffalo 46
Seoul 44
Woodbridge 39
Bremen 36
Philadelphia 36
Helsinki 35
Ho Chi Minh City 32
Boardman 31
Brussels 31
Milan 30
New York 30
Houston 27
Hanoi 24
Hefei 23
São Paulo 21
Nanjing 19
Kocaeli 17
Brno 16
Santa Clara 16
Toronto 16
Monmouth Junction 15
Frankfurt am Main 14
Redondo Beach 14
Tokyo 14
Chennai 13
Rome 12
Dallas 11
Norwalk 11
Sacramento 11
Torino 11
Cotonou 10
Nanchang 10
Turku 10
Warsaw 10
Ankara 9
Jinan 9
Novara 9
Seattle 9
Stockholm 9
Boston 8
Brasília 8
Brooklyn 8
Chicago 8
Dong Ket 8
Fairfield 8
Poplar 8
Zanjan 8
Ardabil 7
Falkenstein 7
Guangzhou 7
Leawood 7
Montreal 7
Shenyang 7
Amsterdam 6
Biên Hòa 6
Denver 6
Guarulhos 6
Kunming 6
London 6
Orem 6
Phoenix 6
Salerno 6
Asti 5
Boltiere 5
Johannesburg 5
Manchester 5
Mexico City 5
Mumbai 5
Nova Iguaçu 5
Nuremberg 5
Porto Alegre 5
San Francisco 5
San Marzano sul Sarno 5
Straubing 5
Tashkent 5
Tianjin 5
Zhengzhou 5
Arriaga 4
Atlanta 4
Bangalore 4
Bexley 4
Cepagatti 4
Totale 4.760
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Nome #
ELEMENTI DI GALENICA CON ESERCIZI DI TARIFFAZIONE 190
Identification of potent triazolylpyridine nicotinamide phosphoribosyltransferase (NAMPT) inhibitors bearing a 1,2,3-triazole tail group 143
Inhibitors of Nicotinamide Phosphoribosyltransferase, compositions, products and uses thereof. 140
Design, synthesis, and biological evaluation of combretabenzodiazepines: a novel class of anti-tubulin agents 139
Targeting Transient Receptor Potential Vanilloid 1 (TRPV1) Channel Softly: The Discovery of Passerini Adducts as a Topical Treatment for Inflammatory Skin Disorders 128
Preparazioni galeniche Esercizi di tariffazione secondo la nuova TNM 127
A Concise Synthesis of Pyrazole Analogues of Combretastatin A1 as Potent Antitubulin Agents 126
Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity 126
Metabolic fate of combretastatin A-1: LC-DAD-MS/MS investigation and biological evaluation of its reactive metabolites 124
Are 1,4- and 1,5-Disubstituted 1,2,3-Triazoles Good Pharmacophoric Groups? 123
La spettrometria di massa negli studi di stabilità dei farmaci 120
Development and validation of a stability-indicating HPLC-UV method for the determination of Thiocolchicoside and its degradation products 115
Biological effects of combined resveratrol and vitamin D3 on ovarian tissue 113
CHEMICAL STABILITY STUDIES OF PROPARGYLAMINE-CONTAINING DRUGS 111
Pyrtriazoles, a Novel Class of Store-Operated Calcium Entry Modulators: Discovery, Biological Profiling, and in Vivo Proof-of-Concept Efficacy in Acute Pancreatitis 111
Identification of a Potent Phosphoinositide 3-Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs 110
FORCED DEGRADATION STUDY OF TIOCOLCHICOSIDE: HPLC-MS CHARACTERIZATION OF DEGRADATION PRODUCTS 107
DETERMINAZIONE HPLC SIMULTANEA DELLA GUAIFENESINA E DEL METILE E PROPILE p-IDROSSIBENZOATO IN UNA FORMULAZIONE LIQUIDA 105
Elementi di galenica con esercizi di tariffazione 100
CHEMICAL STABILITY STUDIES OF PROPARGYLAMINE CONTAINING-DRUGS 99
Data on metabolic stability, aqueous solubility and CYP inhibition of novel triazole-based nicotinamide phosphoribosyltransferase (NAMPT) inhibitors 99
Synthesis and antibronchospastic activity of theophylline thioacetal derivatives 98
Synthesis of a squalenoid oxaziridine and other new classes of squalene derivatives, as inhibitors of sterol biosynthesis 98
New insights in the metabolism of oxybutynin: evidence of N-oxidation of propargylamine moiety and rearrangement to enaminoketone 98
3-carboxy-4-nitrophenyl-dithio-1,1',2-trisnorsqualene: a site-directed inactivator of yeast oxidosqualene cyclase 96
Regioselective Suzuki coupling of dihaloheteroaromatic compounds as a rapid strategy to synthesize potent rigid combretastatin analogues 96
2,3-epoxy-10-aza-10,11-dihydrosqualene, an high-energy intermediate analogue inhibitor of 2,3-oxidosqualene cyclase 95
DEVELOPMENT AND VALIDATION OF HPLC-UV STABILITY INDICATING METHOD FOR THE DETERMINATION OF THIOCOLCHICOSIDE AND ITS DEGRADATION PRODUCTS IN PHARMACEUTICAL DOSAGE FORM 95
FORCED DEGRADATION STUDY OF DOXOFYLLINE: HPLC-MS CHARACTERIZATION OF DEGRADATION PRODUCTS IN BULK DRUG 93
New insights in oxybutynin chemical stability: Identification in transdermal patches of a new impurity arising from oxybutynin N-oxide rearrangement 93
Development and validation of a stability-indicating LC–UV method for the determination of pantethine and its degradation product based on a forced degradation study 92
FORCED DEGRADATION OF DOXOFYLLINE IN BULK DRUG: IDENTIFICATION OF THREE DEGRADATION PRODUCTS 89
IN VITRO METABOLISM STUDY OF ISOPROPYL-9H-THIOXANTHEN-9-ONE (ITX) IN RAT LIVER MICROSOMES 89
In vitro metabolism of 1,3-dioxane, 1,3-oxathiolane and 1,3-dithiane derivatives of theophylline: a structure-metabolism correlation study 88
Azasqualene alcohol and derivatives new selective inhibitors of 2,3-oxidosqualene cyclase 88
Semicarbazide Hydrochloride as Impurity in Drug Substances: a Validated LC-DAD-UV Method for Its Determination in Carbazochrome and Carbazochrome Sodium Sulfonate 88
2,3,4,5-tetrahydroxy-5- (4-hydroxyphenyl)valeric acid: a new cleavable monofunctional reagent for monoclonal antibody labeling 87
Identification of 2,3-diaminophenazine and of o-benzoquinone dioxime as the major in vitro metabolites of benzofuroxan 86
In vitro metabolism of Bumetanide 85
2,3-Oxidosqualene cyclase: from azasqualenes to new site-directed inhibitors 85
Development and validation of a solid-phase extraction and gas chromatography–tandem mass spectrometry method for the determination of isopropyl-9H-thioxanthen-9-one in carton packaged milk 85
Development and validation of a stability-indicating HPLC-UV method for the determination of alizapride and its degradation products 85
Troxerutin, a mixture of O-hydroxyethyl derivatives of the natural flavonoid rutin: Chemical stability and analytical aspects 84
A new approach in the synthesis of immunotoxins ribosome inactivating protein non covalently bound to monoclonal antibody 82
Kinetics of ABC-99 in the rat 80
Role of chocolate consumption in the inflammatory pathway: a proteomic approach 80
Thiol-modifying inhibitors for understanding squalene cyclase function 78
In vitro metabolism study of 2-isopropyl-9H-thioxanthen-9-one (2-ITX) in rat and human: evidence for the formation of an epoxide metabolite 78
Forced degradation study of thiocolchicoside: Characterization of its degradation products 77
SIMULTANEOUS DETERMINATION OF SEROTONIN AND CATECHOLAMINES IN RAT BRAIN BY LC-MS/MS 77
2-aza-2,3-dihydrosqualene:biodistribution and pharmacokinetic properties in mice 76
LC-ESI-MS/MS CHARACTERIZATION OF DEGRADATION PRODUCTS OF TROPANE ALKALOIDS IN BELLADONNA DRY EXTRACT 76
Drug design based on biosynthetic studies: synthesis, biological activity and kinetics of new inhibitors of 2,3-oxido squalene cyclase and squalene epoxidase 75
Synthesis and biological activity of 19-azasqualene 2,3-epoxide as inhibitor of 2,3-oxidosqualene cyclase 75
A new "solid phase" procedure to synthetize immunotoxins 75
Metabolism of 4-(3-cyclohexylpropionyl)-1-(2-ethoxyphenyl)piperazine (D-16120) by rat liver microsomes 75
Doxofylline in rat brain in relation to locomotor activity - Drug Metabolism and Disposition 75
In vitro metabolism study of combretastatin A-4 in rat and human liver microsomes 74
FORCED DEGRADATION STUDY OF OXYBUTYNIN: NEW INSIGHTS FROM LC-MS/MS ANALYSIS ON ITS CHEMICAL STABILITY 73
Synthesis of squalenoid acetylenes and allenes, as inhibitors of squalene epoxidase 73
IN VITRO METABOLIC FATE OF COMBRETASTATIN A-4: EVIDENCE FOR THE FORMATION OF A SULPHATE CONJUGATE METABOLITE 72
Metabolism of Doxophylline by rat liver microsomes 72
In vitro metabolic fate of alizapride: evidence for the formation of reactive metabolites based on liquid chromatography-tandem mass spectrometry 70
IN VITRO, IN VIVO METABOLISM STUDY OF COMBRETASTATIN A-4 IN RAT AND HUMAN 70
In vitro metabolism of 2-(5-ethylpyridin-2-yl)benzimidazole 70
Nitroanilines are the reduction products of benzofuroxan system by oxyhemoglobin (HbO22+) 69
Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis 69
HPLC DETERMINATION OF DOXOFYLLINE AND ITS DEGRADATION PRODUCTS IN DRUG SUBSTANCE: DEVELOPMENT AND VALIDATION 68
Metabolic Fate of the Isocyanide Moiety: Are Isocyanides Pharmacophore Groups Neglected by Medicinal Chemists? 68
An Unexpected Deuterium-Induced Metabolic Switch in Doxophylline 67
LC-ESI-MS/MS characterization of strophanthin-K 67
Metabolismo in vitro della 7-(3-acetil-1,3-tiazolidin-2-ilmetil)teofillina: solfossidazione diastereoselettiva 66
NO-Donor 1,4-dihydropyridine analogues of Amlodipine 66
IN VITRO METABOLISM OF ALIZAPRIDE: EVIDENCE FOR THE FORMATION OF ACROLEIN IN RAT LIVER MICROSOMES 66
In vitro metabolism of azasqualene derivatives and their effects on aminopyrine N-demethylase activity in rat liver microsomes 66
The metabolic fate of the anti-Parkinsonian drug Budipine in rats 65
LC-MS CHARACTERIZATION OF THE IN VITRO METABOLITES OF ALIZAPRIDE 65
Toxin-targeted design for anticancer therapy - Part I. Synthesis and biological evaluation of new thioimidate heterobifunctional reagents 65
In vitro metabolism of N-picolyl-3,5-dimethylbenzamides 64
In vitro metabolism study of 2-isopropyl-9H-thioxanthen-9-one (2-ITX) in rat and human: Evidence for the formation of an epoxide metabolite 64
Metabolism of 1,1-dichloro-cis-diphenylcyclopropane by rat liver microsomes 64
Synthesis and biological activity of a squalenoid maleimide and other classes of squalene derivatives as irreversible inhibitors of 2,3-oxidosqualene cyclase 63
Thermolysis of 4-(2-azido-3-nitrophenyl)-1,4-dihydropyridines as sources of b-carboline derivatives and some related compounds 62
Solubilization and identification of essential functional groups of Candida albicans oxidosqualene cyclase 61
Pharmacokinetic of an antibody-ricin conjugate administered intraperitoneally to mice 61
Formation of lecithin-based microemulsions containing n-alkanol phosphocholines 61
IN VITRO METABOLIC FATE OF COMBRETASTATIN A-4: EVIDENCE FOR THE FORMATION OF QUINONE METABOLITES 60
LC-MS ANALYSIS OF BITTER PRINCIPLES OF ARTEMISIA ABSINTHIUM L 59
Identification of the human UDP-glucuronosyltransferases involved in the glucuronidation of combretastatin A-4. Drug Metabolism and Disposition 59
LC-MS CHARACTERIZATION OF IN VITRO METABOLISM OF COMBRETASTATIN A-4 57
The Metabolic Fate of isoCombretastatin A-4 in Human Liver Microsomes: Identification, Synthesis and Biological Evaluation of Metabolites. 57
In vitro and in vivo phase II metabolism of combretastatin A-4: evidence for the formation of a sulphate conjugate metabolite 57
Metabolism of 7-(1,3-thiazolidin-2-ylmethyl)theophylline by rat liver microsomes: evidence for a monooxygenase-dependent step in 1,3-thiazolidine ring cleavage 57
Lack of in vitro interactions using human liver microsomes between rabeprazole and anticancer drugs 56
LC-MS CHARACTERIZATION OF K-STROPHANTHIN 55
Metabolism of 7-(1,3-dithiolan-2-ylmethyl)-1,3-dimethylxanthine (ABC-99) by rat liver microsomes: diastereoselective metabolism of the 1,3-dithiolane ring 55
IN VITRO METABOLISM STUDY OF ISOPROPYL-9H-THIOXANTHEN-9-ONE (ITX) IN RAT AND HUMAN LIVER MICROSOMES 51
Simultaneous, stability indicating, HPLC-DAD determination of guaifenesin and methyl and propyl-parabens in cough syrup 49
Interactions between rabeprazole and anticancer drugs 48
In vivo metabolism of the anti-inflammatory agent 2-(5-ethyl-pyridin-2-yl)benzimidazole (KB-1043) 48
Totale 8.337
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Categoria #
all - tutte 42.486
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 42.486
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021530 0 0 0 0 0 67 113 7 113 41 132 57
2021/2022928 62 27 161 144 46 5 79 20 50 65 91 178
2022/20231.713 114 53 80 71 145 187 48 110 794 8 56 47
2023/2024431 47 33 34 7 78 3 98 14 0 14 36 67
2024/20251.038 33 20 43 24 40 90 133 54 276 118 31 176
2025/20261.434 165 119 259 515 341 35 0 0 0 0 0 0
Totale 8.427