IRIS
GROSA, Giorgio
 Distribuzione geografica
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Continente #
EU - Europa 4.198
NA - Nord America 3.504
AS - Asia 2.071
SA - Sud America 269
AF - Africa 53
Continente sconosciuto - Info sul continente non disponibili 9
OC - Oceania 1
Totale 10.105
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Nazione #
US - Stati Uniti d'America 3.435
RU - Federazione Russa 893
IE - Irlanda 764
CN - Cina 617
SG - Singapore 570
SE - Svezia 535
DE - Germania 521
IT - Italia 501
UA - Ucraina 358
HK - Hong Kong 287
VN - Vietnam 265
FI - Finlandia 216
BR - Brasile 207
FR - Francia 149
IN - India 114
GB - Regno Unito 113
KR - Corea 49
CA - Canada 38
TR - Turchia 35
BE - Belgio 32
IR - Iran 29
EE - Estonia 25
AR - Argentina 24
MX - Messico 23
BD - Bangladesh 18
CZ - Repubblica Ceca 18
ES - Italia 18
JP - Giappone 17
IQ - Iraq 15
PL - Polonia 15
ZA - Sudafrica 12
BJ - Benin 10
EC - Ecuador 10
ID - Indonesia 10
LT - Lituania 10
PK - Pakistan 10
EU - Europa 9
MA - Marocco 8
CL - Cile 7
NL - Olanda 7
PY - Paraguay 5
UZ - Uzbekistan 5
VE - Venezuela 5
AT - Austria 4
BG - Bulgaria 4
CH - Svizzera 4
CO - Colombia 4
EG - Egitto 4
PE - Perù 4
SA - Arabia Saudita 4
TH - Thailandia 4
TW - Taiwan 4
DZ - Algeria 3
ET - Etiopia 3
GE - Georgia 3
GR - Grecia 3
HN - Honduras 3
PH - Filippine 3
TN - Tunisia 3
AE - Emirati Arabi Uniti 2
BO - Bolivia 2
CI - Costa d'Avorio 2
DK - Danimarca 2
JO - Giordania 2
KE - Kenya 2
NP - Nepal 2
RO - Romania 2
AL - Albania 1
AO - Angola 1
BW - Botswana 1
CG - Congo 1
DM - Dominica 1
GA - Gabon 1
GT - Guatemala 1
HU - Ungheria 1
IL - Israele 1
KW - Kuwait 1
LB - Libano 1
LK - Sri Lanka 1
LV - Lettonia 1
MY - Malesia 1
NG - Nigeria 1
NZ - Nuova Zelanda 1
PA - Panama 1
PR - Porto Rico 1
PT - Portogallo 1
SN - Senegal 1
TM - Turkmenistan 1
TT - Trinidad e Tobago 1
UY - Uruguay 1
Totale 10.105
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Città #
Dublin 764
Jacksonville 588
Hong Kong 286
Dearborn 280
Chandler 261
Singapore 230
San Jose 227
Beijing 221
Ashburn 189
Wilmington 154
Ann Arbor 147
Piemonte 128
Moscow 127
Lawrence 100
Princeton 100
Los Angeles 98
Lauterbourg 82
Ho Chi Minh City 81
San Mateo 81
Andover 68
Munich 66
Hanoi 63
Buffalo 46
Seoul 45
Woodbridge 39
Bremen 36
Philadelphia 36
Helsinki 35
New York 35
Brussels 32
Boardman 31
Milan 31
Houston 27
São Paulo 26
Hefei 24
Orem 23
Guangzhou 21
Frankfurt am Main 20
Nanjing 20
Chennai 19
Santa Clara 18
Kocaeli 17
Toronto 17
Brno 16
Monmouth Junction 15
Rome 15
Redondo Beach 14
Tokyo 14
Dallas 13
Tianjin 12
Warsaw 12
Norwalk 11
Sacramento 11
Torino 11
Cotonou 10
Da Nang 10
Haiphong 10
Hangzhou 10
Montreal 10
Nanchang 10
Turku 10
Ankara 9
Brasília 9
Denver 9
Jinan 9
London 9
Novara 9
Seattle 9
Stockholm 9
Boston 8
Brooklyn 8
Chicago 8
Council Bluffs 8
Dong Ket 8
Fairfield 8
Falkenstein 8
Johannesburg 8
Mexico City 8
Poplar 8
Shenyang 8
Zanjan 8
Zhengzhou 8
Amsterdam 7
Ardabil 7
Biên Hòa 7
Chengdu 7
Leawood 7
Manchester 7
Nuremberg 7
Baghdad 6
Guarulhos 6
Kunming 6
Mumbai 6
Phoenix 6
Salerno 6
Shanghai 6
Asti 5
Atlanta 5
Boltiere 5
Nova Iguaçu 5
Totale 5.440
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Nome #
ELEMENTI DI GALENICA CON ESERCIZI DI TARIFFAZIONE 210
Design, synthesis, and biological evaluation of combretabenzodiazepines: a novel class of anti-tubulin agents 170
Identification of potent triazolylpyridine nicotinamide phosphoribosyltransferase (NAMPT) inhibitors bearing a 1,2,3-triazole tail group 165
Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity 161
A Concise Synthesis of Pyrazole Analogues of Combretastatin A1 as Potent Antitubulin Agents 158
Inhibitors of Nicotinamide Phosphoribosyltransferase, compositions, products and uses thereof. 158
Targeting Transient Receptor Potential Vanilloid 1 (TRPV1) Channel Softly: The Discovery of Passerini Adducts as a Topical Treatment for Inflammatory Skin Disorders 154
Preparazioni galeniche Esercizi di tariffazione secondo la nuova TNM 154
Metabolic fate of combretastatin A-1: LC-DAD-MS/MS investigation and biological evaluation of its reactive metabolites 151
Are 1,4- and 1,5-Disubstituted 1,2,3-Triazoles Good Pharmacophoric Groups? 151
Pyrtriazoles, a Novel Class of Store-Operated Calcium Entry Modulators: Discovery, Biological Profiling, and in Vivo Proof-of-Concept Efficacy in Acute Pancreatitis 147
Development and validation of a stability-indicating HPLC-UV method for the determination of Thiocolchicoside and its degradation products 145
La spettrometria di massa negli studi di stabilità dei farmaci 141
CHEMICAL STABILITY STUDIES OF PROPARGYLAMINE-CONTAINING DRUGS 135
Biological effects of combined resveratrol and vitamin D3 on ovarian tissue 135
Identification of a Potent Phosphoinositide 3-Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs 131
DETERMINAZIONE HPLC SIMULTANEA DELLA GUAIFENESINA E DEL METILE E PROPILE p-IDROSSIBENZOATO IN UNA FORMULAZIONE LIQUIDA 127
Data on metabolic stability, aqueous solubility and CYP inhibition of novel triazole-based nicotinamide phosphoribosyltransferase (NAMPT) inhibitors 126
FORCED DEGRADATION STUDY OF TIOCOLCHICOSIDE: HPLC-MS CHARACTERIZATION OF DEGRADATION PRODUCTS 125
Regioselective Suzuki coupling of dihaloheteroaromatic compounds as a rapid strategy to synthesize potent rigid combretastatin analogues 125
CHEMICAL STABILITY STUDIES OF PROPARGYLAMINE CONTAINING-DRUGS 122
Elementi di galenica con esercizi di tariffazione 120
Development and validation of a stability-indicating LC–UV method for the determination of pantethine and its degradation product based on a forced degradation study 119
New insights in the metabolism of oxybutynin: evidence of N-oxidation of propargylamine moiety and rearrangement to enaminoketone 118
2,3-epoxy-10-aza-10,11-dihydrosqualene, an high-energy intermediate analogue inhibitor of 2,3-oxidosqualene cyclase 115
New insights in oxybutynin chemical stability: Identification in transdermal patches of a new impurity arising from oxybutynin N-oxide rearrangement 113
A new approach in the synthesis of immunotoxins ribosome inactivating protein non covalently bound to monoclonal antibody 112
DEVELOPMENT AND VALIDATION OF HPLC-UV STABILITY INDICATING METHOD FOR THE DETERMINATION OF THIOCOLCHICOSIDE AND ITS DEGRADATION PRODUCTS IN PHARMACEUTICAL DOSAGE FORM 112
Troxerutin, a mixture of O-hydroxyethyl derivatives of the natural flavonoid rutin: Chemical stability and analytical aspects 112
FORCED DEGRADATION STUDY OF DOXOFYLLINE: HPLC-MS CHARACTERIZATION OF DEGRADATION PRODUCTS IN BULK DRUG 111
3-carboxy-4-nitrophenyl-dithio-1,1',2-trisnorsqualene: a site-directed inactivator of yeast oxidosqualene cyclase 110
Synthesis and antibronchospastic activity of theophylline thioacetal derivatives 109
Development and validation of a stability-indicating HPLC-UV method for the determination of alizapride and its degradation products 109
Synthesis of a squalenoid oxaziridine and other new classes of squalene derivatives, as inhibitors of sterol biosynthesis 108
2,3,4,5-tetrahydroxy-5- (4-hydroxyphenyl)valeric acid: a new cleavable monofunctional reagent for monoclonal antibody labeling 108
Azasqualene alcohol and derivatives new selective inhibitors of 2,3-oxidosqualene cyclase 106
Semicarbazide Hydrochloride as Impurity in Drug Substances: a Validated LC-DAD-UV Method for Its Determination in Carbazochrome and Carbazochrome Sodium Sulfonate 106
Development and validation of a solid-phase extraction and gas chromatography–tandem mass spectrometry method for the determination of isopropyl-9H-thioxanthen-9-one in carton packaged milk 104
In vitro metabolism of 1,3-dioxane, 1,3-oxathiolane and 1,3-dithiane derivatives of theophylline: a structure-metabolism correlation study 103
Identification of 2,3-diaminophenazine and of o-benzoquinone dioxime as the major in vitro metabolites of benzofuroxan 103
FORCED DEGRADATION OF DOXOFYLLINE IN BULK DRUG: IDENTIFICATION OF THREE DEGRADATION PRODUCTS 102
IN VITRO METABOLISM STUDY OF ISOPROPYL-9H-THIOXANTHEN-9-ONE (ITX) IN RAT LIVER MICROSOMES 102
2,3-Oxidosqualene cyclase: from azasqualenes to new site-directed inhibitors 100
In vitro metabolism of Bumetanide 98
Kinetics of ABC-99 in the rat 96
Doxofylline in rat brain in relation to locomotor activity - Drug Metabolism and Disposition 95
Thiol-modifying inhibitors for understanding squalene cyclase function 94
A new "solid phase" procedure to synthetize immunotoxins 93
Forced degradation study of thiocolchicoside: Characterization of its degradation products 93
LC-ESI-MS/MS CHARACTERIZATION OF DEGRADATION PRODUCTS OF TROPANE ALKALOIDS IN BELLADONNA DRY EXTRACT 93
Role of chocolate consumption in the inflammatory pathway: a proteomic approach 93
An Unexpected Deuterium-Induced Metabolic Switch in Doxophylline 92
Drug design based on biosynthetic studies: synthesis, biological activity and kinetics of new inhibitors of 2,3-oxido squalene cyclase and squalene epoxidase 91
In vitro metabolism study of combretastatin A-4 in rat and human liver microsomes 91
In vitro metabolism study of 2-isopropyl-9H-thioxanthen-9-one (2-ITX) in rat and human: evidence for the formation of an epoxide metabolite 91
SIMULTANEOUS DETERMINATION OF SEROTONIN AND CATECHOLAMINES IN RAT BRAIN BY LC-MS/MS 89
Synthesis and biological activity of 19-azasqualene 2,3-epoxide as inhibitor of 2,3-oxidosqualene cyclase 88
2-aza-2,3-dihydrosqualene:biodistribution and pharmacokinetic properties in mice 88
FORCED DEGRADATION STUDY OF OXYBUTYNIN: NEW INSIGHTS FROM LC-MS/MS ANALYSIS ON ITS CHEMICAL STABILITY 88
Metabolic Fate of the Isocyanide Moiety: Are Isocyanides Pharmacophore Groups Neglected by Medicinal Chemists? 87
In vitro metabolism of 2-(5-ethylpyridin-2-yl)benzimidazole 86
Metabolism of Doxophylline by rat liver microsomes 85
Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis 85
IN VITRO METABOLIC FATE OF COMBRETASTATIN A-4: EVIDENCE FOR THE FORMATION OF A SULPHATE CONJUGATE METABOLITE 84
IN VITRO METABOLISM OF ALIZAPRIDE: EVIDENCE FOR THE FORMATION OF ACROLEIN IN RAT LIVER MICROSOMES 84
Metabolism of 4-(3-cyclohexylpropionyl)-1-(2-ethoxyphenyl)piperazine (D-16120) by rat liver microsomes 84
IN VITRO, IN VIVO METABOLISM STUDY OF COMBRETASTATIN A-4 IN RAT AND HUMAN 83
Solubilization and identification of essential functional groups of Candida albicans oxidosqualene cyclase 82
In vitro metabolic fate of alizapride: evidence for the formation of reactive metabolites based on liquid chromatography-tandem mass spectrometry 82
LC-MS CHARACTERIZATION OF THE IN VITRO METABOLITES OF ALIZAPRIDE 82
Synthesis of squalenoid acetylenes and allenes, as inhibitors of squalene epoxidase 82
In vitro metabolism of N-picolyl-3,5-dimethylbenzamides 80
Nitroanilines are the reduction products of benzofuroxan system by oxyhemoglobin (HbO22+) 80
HPLC DETERMINATION OF DOXOFYLLINE AND ITS DEGRADATION PRODUCTS IN DRUG SUBSTANCE: DEVELOPMENT AND VALIDATION 79
Identification of the human UDP-glucuronosyltransferases involved in the glucuronidation of combretastatin A-4. Drug Metabolism and Disposition 79
New Hyaluronic Acid from Plant Origin to Improve Joint Protection—An In Vitro Study 78
In vitro metabolism of azasqualene derivatives and their effects on aminopyrine N-demethylase activity in rat liver microsomes 78
Metabolismo in vitro della 7-(3-acetil-1,3-tiazolidin-2-ilmetil)teofillina: solfossidazione diastereoselettiva 77
Synthesis and biological activity of a squalenoid maleimide and other classes of squalene derivatives as irreversible inhibitors of 2,3-oxidosqualene cyclase 77
Metabolism of 1,1-dichloro-cis-diphenylcyclopropane by rat liver microsomes 76
The metabolic fate of the anti-Parkinsonian drug Budipine in rats 75
NO-Donor 1,4-dihydropyridine analogues of Amlodipine 75
In vitro metabolism study of 2-isopropyl-9H-thioxanthen-9-one (2-ITX) in rat and human: Evidence for the formation of an epoxide metabolite 75
LC-ESI-MS/MS characterization of strophanthin-K 74
Toxin-targeted design for anticancer therapy - Part I. Synthesis and biological evaluation of new thioimidate heterobifunctional reagents 74
Pharmacokinetic of an antibody-ricin conjugate administered intraperitoneally to mice 73
Thermolysis of 4-(2-azido-3-nitrophenyl)-1,4-dihydropyridines as sources of b-carboline derivatives and some related compounds 73
IN VITRO METABOLIC FATE OF COMBRETASTATIN A-4: EVIDENCE FOR THE FORMATION OF QUINONE METABOLITES 72
The Metabolic Fate of isoCombretastatin A-4 in Human Liver Microsomes: Identification, Synthesis and Biological Evaluation of Metabolites. 71
Formation of lecithin-based microemulsions containing n-alkanol phosphocholines 71
In vitro and in vivo phase II metabolism of combretastatin A-4: evidence for the formation of a sulphate conjugate metabolite 71
Metabolism of 7-(1,3-thiazolidin-2-ylmethyl)theophylline by rat liver microsomes: evidence for a monooxygenase-dependent step in 1,3-thiazolidine ring cleavage 71
LC-MS CHARACTERIZATION OF IN VITRO METABOLISM OF COMBRETASTATIN A-4 70
LC-MS CHARACTERIZATION OF K-STROPHANTHIN 69
Lack of in vitro interactions using human liver microsomes between rabeprazole and anticancer drugs 69
Metabolism of 7-(1,3-dithiolan-2-ylmethyl)-1,3-dimethylxanthine (ABC-99) by rat liver microsomes: diastereoselective metabolism of the 1,3-dithiolane ring 69
LC-MS ANALYSIS OF BITTER PRINCIPLES OF ARTEMISIA ABSINTHIUM L 67
Simultaneous, stability indicating, HPLC-DAD determination of guaifenesin and methyl and propyl-parabens in cough syrup 65
In vivo metabolism of the anti-inflammatory agent 2-(5-ethyl-pyridin-2-yl)benzimidazole (KB-1043) 65
IN VITRO METABOLISM STUDY OF ISOPROPYL-9H-THIOXANTHEN-9-ONE (ITX) IN RAT AND HUMAN LIVER MICROSOMES 63
Totale 10.088
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Categoria #
all - tutte 45.859
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 45.859
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021230 0 0 0 0 0 0 0 0 0 41 132 57
2021/2022928 62 27 161 144 46 5 79 20 50 65 91 178
2022/20231.713 114 53 80 71 145 187 48 110 794 8 56 47
2023/2024431 47 33 34 7 78 3 98 14 0 14 36 67
2024/20251.038 33 20 43 24 40 90 133 54 276 118 31 176
2025/20263.208 165 119 259 515 341 270 474 614 226 225 0 0
Totale 10.201