IRIS
GROSA, Giorgio
 Distribuzione geografica
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Continente #
EU - Europa 2.834
NA - Nord America 2.531
AS - Asia 510
Continente sconosciuto - Info sul continente non disponibili 9
SA - Sud America 7
AF - Africa 1
Totale 5.892
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Nazione #
US - Stati Uniti d'America 2.514
IE - Irlanda 760
SE - Svezia 526
IT - Italia 447
DE - Germania 418
UA - Ucraina 339
CN - Cina 201
FI - Finlandia 190
HK - Hong Kong 92
SG - Singapore 77
IN - India 71
GB - Regno Unito 67
BE - Belgio 29
IR - Iran 29
TR - Turchia 26
FR - Francia 18
CZ - Repubblica Ceca 17
CA - Canada 13
RU - Federazione Russa 12
EU - Europa 9
VN - Vietnam 8
CL - Cile 5
MX - Messico 4
CH - Svizzera 3
GR - Grecia 3
KR - Corea 3
PE - Perù 2
AT - Austria 1
DK - Danimarca 1
EG - Egitto 1
IQ - Iraq 1
JP - Giappone 1
LT - Lituania 1
NL - Olanda 1
PK - Pakistan 1
PL - Polonia 1
Totale 5.892
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Città #
Dublin 760
Jacksonville 588
Dearborn 280
Chandler 261
Wilmington 154
Ann Arbor 147
Piemonte 128
Lawrence 100
Princeton 100
Hong Kong 92
Beijing 88
San Mateo 81
Andover 68
Ashburn 54
Singapore 43
Woodbridge 39
Bremen 36
Philadelphia 36
Boardman 31
Brussels 29
Houston 26
Hefei 23
Helsinki 20
Milan 19
Nanjing 19
Kocaeli 17
Munich 17
Brno 16
Monmouth Junction 15
Toronto 12
Norwalk 11
Sacramento 11
Torino 11
Nanchang 10
Jinan 9
Rome 9
Dong Ket 8
Fairfield 8
Zanjan 8
Ardabil 7
Guangzhou 7
Leawood 7
Shenyang 7
Ankara 6
Kunming 6
Salerno 6
Asti 5
Boltiere 5
Los Angeles 5
San Marzano sul Sarno 5
Straubing 5
Zhengzhou 5
Arriaga 4
Bangalore 4
Cepagatti 4
Formigine 4
Giussano 4
Grignasco 4
Seattle 4
Strasbourg 4
Athens 3
Bari 3
Chengdu 3
Chongqing 3
Como 3
Garbagnate Milanese 3
Grafing 3
Kecioeren 3
La Canada Flintridge 3
Maccacari 3
Messina 3
Muro Lucano 3
Nürnberg 3
Ospitaletto 3
Padova 3
Rende 3
Saint-Prex 3
San Diego 3
Abano Terme 2
Berlin 2
Cambridge 2
Casalnuovo di Napoli 2
Cerano 2
Clearwater 2
Cosenza 2
Düsseldorf 2
Ferrara 2
Florence 2
Fuzhou 2
Gandosso 2
Hebei 2
Lima 2
Modena 2
Novara 2
Pavia 2
Phoenix 2
San Francisco 2
Santiago 2
Tuscania 2
Villapriolo 2
Totale 3.590
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Nome #
ELEMENTI DI GALENICA CON ESERCIZI DI TARIFFAZIONE 165
Identification of potent triazolylpyridine nicotinamide phosphoribosyltransferase (NAMPT) inhibitors bearing a 1,2,3-triazole tail group 107
Inhibitors of Nicotinamide Phosphoribosyltransferase, compositions, products and uses thereof. 104
Metabolic fate of combretastatin A-1: LC-DAD-MS/MS investigation and biological evaluation of its reactive metabolites 98
Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity 96
Design, synthesis, and biological evaluation of combretabenzodiazepines: a novel class of anti-tubulin agents 95
Preparazioni galeniche Esercizi di tariffazione secondo la nuova TNM 94
La spettrometria di massa negli studi di stabilità dei farmaci 89
Targeting Transient Receptor Potential Vanilloid 1 (TRPV1) Channel Softly: The Discovery of Passerini Adducts as a Topical Treatment for Inflammatory Skin Disorders 88
FORCED DEGRADATION STUDY OF TIOCOLCHICOSIDE: HPLC-MS CHARACTERIZATION OF DEGRADATION PRODUCTS 83
CHEMICAL STABILITY STUDIES OF PROPARGYLAMINE-CONTAINING DRUGS 81
A Concise Synthesis of Pyrazole Analogues of Combretastatin A1 as Potent Antitubulin Agents 81
Development and validation of a stability-indicating HPLC-UV method for the determination of Thiocolchicoside and its degradation products 80
Biological effects of combined resveratrol and vitamin D3 on ovarian tissue 79
Synthesis of a squalenoid oxaziridine and other new classes of squalene derivatives, as inhibitors of sterol biosynthesis 78
Elementi di galenica con esercizi di tariffazione 77
Identification of a Potent Phosphoinositide 3-Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs 77
Synthesis and antibronchospastic activity of theophylline thioacetal derivatives 75
Are 1,4- and 1,5-Disubstituted 1,2,3-Triazoles Good Pharmacophoric Groups? 72
CHEMICAL STABILITY STUDIES OF PROPARGYLAMINE CONTAINING-DRUGS 72
Pyrtriazoles, a Novel Class of Store-Operated Calcium Entry Modulators: Discovery, Biological Profiling, and in Vivo Proof-of-Concept Efficacy in Acute Pancreatitis 71
Regioselective Suzuki coupling of dihaloheteroaromatic compounds as a rapid strategy to synthesize potent rigid combretastatin analogues 70
In vitro metabolism of 1,3-dioxane, 1,3-oxathiolane and 1,3-dithiane derivatives of theophylline: a structure-metabolism correlation study 69
In vitro metabolism of Bumetanide 67
Thiol-modifying inhibitors for understanding squalene cyclase function 67
Kinetics of ABC-99 in the rat 66
DEVELOPMENT AND VALIDATION OF HPLC-UV STABILITY INDICATING METHOD FOR THE DETERMINATION OF THIOCOLCHICOSIDE AND ITS DEGRADATION PRODUCTS IN PHARMACEUTICAL DOSAGE FORM 66
2,3-epoxy-10-aza-10,11-dihydrosqualene, an high-energy intermediate analogue inhibitor of 2,3-oxidosqualene cyclase 65
FORCED DEGRADATION STUDY OF DOXOFYLLINE: HPLC-MS CHARACTERIZATION OF DEGRADATION PRODUCTS IN BULK DRUG 64
New insights in the metabolism of oxybutynin: evidence of N-oxidation of propargylamine moiety and rearrangement to enaminoketone 64
3-carboxy-4-nitrophenyl-dithio-1,1',2-trisnorsqualene: a site-directed inactivator of yeast oxidosqualene cyclase 63
Forced degradation study of thiocolchicoside: Characterization of its degradation products 63
Role of chocolate consumption in the inflammatory pathway: a proteomic approach 63
Development and validation of a stability-indicating LC–UV method for the determination of pantethine and its degradation product based on a forced degradation study 63
SIMULTANEOUS DETERMINATION OF SEROTONIN AND CATECHOLAMINES IN RAT BRAIN BY LC-MS/MS 62
Synthesis of squalenoid acetylenes and allenes, as inhibitors of squalene epoxidase 62
Doxofylline in rat brain in relation to locomotor activity - Drug Metabolism and Disposition 62
Drug design based on biosynthetic studies: synthesis, biological activity and kinetics of new inhibitors of 2,3-oxido squalene cyclase and squalene epoxidase 61
Synthesis and biological activity of 19-azasqualene 2,3-epoxide as inhibitor of 2,3-oxidosqualene cyclase 61
DETERMINAZIONE HPLC SIMULTANEA DELLA GUAIFENESINA E DEL METILE E PROPILE p-IDROSSIBENZOATO IN UNA FORMULAZIONE LIQUIDA 61
Identification of 2,3-diaminophenazine and of o-benzoquinone dioxime as the major in vitro metabolites of benzofuroxan 61
New insights in oxybutynin chemical stability: Identification in transdermal patches of a new impurity arising from oxybutynin N-oxide rearrangement 61
FORCED DEGRADATION OF DOXOFYLLINE IN BULK DRUG: IDENTIFICATION OF THREE DEGRADATION PRODUCTS 60
Development and validation of a solid-phase extraction and gas chromatography–tandem mass spectrometry method for the determination of isopropyl-9H-thioxanthen-9-one in carton packaged milk 60
Development and validation of a stability-indicating HPLC-UV method for the determination of alizapride and its degradation products 59
Azasqualene alcohol and derivatives new selective inhibitors of 2,3-oxidosqualene cyclase 58
2,3,4,5-tetrahydroxy-5- (4-hydroxyphenyl)valeric acid: a new cleavable monofunctional reagent for monoclonal antibody labeling 58
In vitro metabolism of 2-(5-ethylpyridin-2-yl)benzimidazole 58
Metabolism of 4-(3-cyclohexylpropionyl)-1-(2-ethoxyphenyl)piperazine (D-16120) by rat liver microsomes 58
Nitroanilines are the reduction products of benzofuroxan system by oxyhemoglobin (HbO22+) 57
Troxerutin, a mixture of O-hydroxyethyl derivatives of the natural flavonoid rutin: Chemical stability and analytical aspects 57
In vitro metabolism of azasqualene derivatives and their effects on aminopyrine N-demethylase activity in rat liver microsomes 56
A new approach in the synthesis of immunotoxins ribosome inactivating protein non covalently bound to monoclonal antibody 55
2,3-Oxidosqualene cyclase: from azasqualenes to new site-directed inhibitors 55
A new "solid phase" procedure to synthetize immunotoxins 55
FORCED DEGRADATION STUDY OF OXYBUTYNIN: NEW INSIGHTS FROM LC-MS/MS ANALYSIS ON ITS CHEMICAL STABILITY 55
Semicarbazide Hydrochloride as Impurity in Drug Substances: a Validated LC-DAD-UV Method for Its Determination in Carbazochrome and Carbazochrome Sodium Sulfonate 54
Data on metabolic stability, aqueous solubility and CYP inhibition of novel triazole-based nicotinamide phosphoribosyltransferase (NAMPT) inhibitors 54
IN VITRO METABOLISM STUDY OF ISOPROPYL-9H-THIOXANTHEN-9-ONE (ITX) IN RAT LIVER MICROSOMES 53
Metabolismo in vitro della 7-(3-acetil-1,3-tiazolidin-2-ilmetil)teofillina: solfossidazione diastereoselettiva 52
The metabolic fate of the anti-Parkinsonian drug Budipine in rats 52
HPLC DETERMINATION OF DOXOFYLLINE AND ITS DEGRADATION PRODUCTS IN DRUG SUBSTANCE: DEVELOPMENT AND VALIDATION 52
In vitro metabolism study of 2-isopropyl-9H-thioxanthen-9-one (2-ITX) in rat and human: evidence for the formation of an epoxide metabolite 51
In vitro metabolism of N-picolyl-3,5-dimethylbenzamides 50
Synthesis and biological activity of a squalenoid maleimide and other classes of squalene derivatives as irreversible inhibitors of 2,3-oxidosqualene cyclase 50
Solubilization and identification of essential functional groups of Candida albicans oxidosqualene cyclase 50
2-aza-2,3-dihydrosqualene:biodistribution and pharmacokinetic properties in mice 50
Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis 50
Metabolic Fate of the Isocyanide Moiety: Are Isocyanides Pharmacophore Groups Neglected by Medicinal Chemists? 50
LC-MS CHARACTERIZATION OF THE IN VITRO METABOLITES OF ALIZAPRIDE 49
In vitro metabolism study of combretastatin A-4 in rat and human liver microsomes 48
LC-MS CHARACTERIZATION OF IN VITRO METABOLISM OF COMBRETASTATIN A-4 47
The Metabolic Fate of isoCombretastatin A-4 in Human Liver Microsomes: Identification, Synthesis and Biological Evaluation of Metabolites. 46
IN VITRO METABOLIC FATE OF COMBRETASTATIN A-4: EVIDENCE FOR THE FORMATION OF A SULPHATE CONJUGATE METABOLITE 46
LC-ESI-MS/MS CHARACTERIZATION OF DEGRADATION PRODUCTS OF TROPANE ALKALOIDS IN BELLADONNA DRY EXTRACT 45
Lack of in vitro interactions using human liver microsomes between rabeprazole and anticancer drugs 45
In vitro metabolism study of 2-isopropyl-9H-thioxanthen-9-one (2-ITX) in rat and human: Evidence for the formation of an epoxide metabolite 45
Metabolism of Doxophylline by rat liver microsomes 45
NO-Donor 1,4-dihydropyridine analogues of Amlodipine 44
LC-MS ANALYSIS OF BITTER PRINCIPLES OF ARTEMISIA ABSINTHIUM L 44
Identification of the human UDP-glucuronosyltransferases involved in the glucuronidation of combretastatin A-4. Drug Metabolism and Disposition 44
LC-ESI-MS/MS characterization of strophanthin-K 43
Toxin-targeted design for anticancer therapy - Part I. Synthesis and biological evaluation of new thioimidate heterobifunctional reagents 43
In vitro and in vivo phase II metabolism of combretastatin A-4: evidence for the formation of a sulphate conjugate metabolite 42
Metabolism of 7-(1,3-thiazolidin-2-ylmethyl)theophylline by rat liver microsomes: evidence for a monooxygenase-dependent step in 1,3-thiazolidine ring cleavage 42
Metabolism of 7-(1,3-dithiolan-2-ylmethyl)-1,3-dimethylxanthine (ABC-99) by rat liver microsomes: diastereoselective metabolism of the 1,3-dithiolane ring 42
In vitro metabolic fate of alizapride: evidence for the formation of reactive metabolites based on liquid chromatography-tandem mass spectrometry 41
IN VITRO, IN VIVO METABOLISM STUDY OF COMBRETASTATIN A-4 IN RAT AND HUMAN 41
LC-MS CHARACTERIZATION OF K-STROPHANTHIN 40
IN VITRO METABOLIC FATE OF COMBRETASTATIN A-4: EVIDENCE FOR THE FORMATION OF QUINONE METABOLITES 40
IN VITRO METABOLISM OF ALIZAPRIDE: EVIDENCE FOR THE FORMATION OF ACROLEIN IN RAT LIVER MICROSOMES 39
Metabolism of 1,1-dichloro-cis-diphenylcyclopropane by rat liver microsomes 38
Formation of lecithin-based microemulsions containing n-alkanol phosphocholines 37
IN VITRO METABOLISM STUDY OF ISOPROPYL-9H-THIOXANTHEN-9-ONE (ITX) IN RAT AND HUMAN LIVER MICROSOMES 37
In vivo metabolism of the anti-inflammatory agent 2-(5-ethyl-pyridin-2-yl)benzimidazole (KB-1043) 37
Pharmacokinetic of an antibody-ricin conjugate administered intraperitoneally to mice 35
Thermolysis of 4-(2-azido-3-nitrophenyl)-1,4-dihydropyridines as sources of b-carboline derivatives and some related compounds 35
Simultaneous, stability indicating, HPLC-DAD determination of guaifenesin and methyl and propyl-parabens in cough syrup 35
Toxin-targeted design for anticancer therapy - Part II. Preparation and biological comparison of different chemically linked gelonin-antibody CONJUGATES 32
Interactions between rabeprazole and anticancer drugs 31
Totale 5.950
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Categoria #
all - tutte 25.855
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 25.855
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.149 6 14 106 9 186 185 240 60 126 77 132 8
2020/2021859 114 3 107 12 93 67 113 7 113 41 132 57
2021/2022928 62 27 161 144 46 5 79 20 50 65 91 178
2022/20231.713 114 53 80 71 145 187 48 110 794 8 56 47
2023/2024431 47 33 34 7 78 3 98 14 0 14 36 67
2024/202531 31 0 0 0 0 0 0 0 0 0 0 0
Totale 5.986