The presence of components of a renin-angiotensin system was investigated in the heart of an African lungfish Protopterus annectens. A renin-like activity is present in heart homogenates. The activity reaches its maximum after 90 min of incubation at 20°C. By a spectrophotometric assay, an angiotensin converting enzyme-like activity was detected. By immunohistochemistry Ile5-Angiotensin II immunoreactive cardiocytes were demonstrated in the atrium and bulbus. Our data indicate that probably a local renin-angiotensin-like system is present in the heart of Protopterus annectens.
A local Renin Angiotensin System in the heart of an African lungfish, Protopterus annectens.
MASINI, MARIA ANGELA
Membro del Collaboration Group
;
1995-01-01
Abstract
The presence of components of a renin-angiotensin system was investigated in the heart of an African lungfish Protopterus annectens. A renin-like activity is present in heart homogenates. The activity reaches its maximum after 90 min of incubation at 20°C. By a spectrophotometric assay, an angiotensin converting enzyme-like activity was detected. By immunohistochemistry Ile5-Angiotensin II immunoreactive cardiocytes were demonstrated in the atrium and bulbus. Our data indicate that probably a local renin-angiotensin-like system is present in the heart of Protopterus annectens.| File | Dimensione | Formato | |
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CompBiochPhysiol1995.pdf
file disponibile agli utenti autorizzati
Descrizione: articolo
Tipologia:
Documento in Post-print
Licenza:
DRM non definito
Dimensione
581.67 kB
Formato
Adobe PDF
|
581.67 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
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