Overall survival (OS) is a composite clinical endpoint in hepatocellular carcinoma due to the mutual influence of cirrhosis and active malignancy in dictating patient's mortality. The ALBI grade is a recently described index of liver dysfunction in HCC, based solely on albumin and bilirubin levels. Whilst accurate, this score lacks cross-validation, especially in intermediate-stage HCC, where OS is highly heterogeneous.

The ALBI grade provides objective hepatic reserve estimation across each BCLC stage of hepatocellular carcinoma

Pinato, David J;ALLARA, Elias;SMIRNE, Carlo;BURLONE, MICHELA Emma;PIRISI, Mario;
2017-01-01

Abstract

Overall survival (OS) is a composite clinical endpoint in hepatocellular carcinoma due to the mutual influence of cirrhosis and active malignancy in dictating patient's mortality. The ALBI grade is a recently described index of liver dysfunction in HCC, based solely on albumin and bilirubin levels. Whilst accurate, this score lacks cross-validation, especially in intermediate-stage HCC, where OS is highly heterogeneous.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11579/77783
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