No information is currently available on genetic determinants of short-term response to drug withdrawal in medication overuse headache (MOH). In the present study, we aimed to evaluate the role of 14 polymorphisms in 8 candidate genes potentially relevant for drug addiction (OPRM1, DRD2, DBH, COMT, BDNF, SLC6A4, 5HT2A, and SLC1A2) as predictors for detoxification outcome of MOH patients at 2 months of follow-up.

Combined effect of common gene variants on response to drug withdrawal therapy in medication overuse headache

CARGNIN, Sarah;VIANA, MICHELE;CANONICO, Pier Luigi;GENAZZANI, Armando;TERRAZZINO, SALVATORE
2014-01-01

Abstract

No information is currently available on genetic determinants of short-term response to drug withdrawal in medication overuse headache (MOH). In the present study, we aimed to evaluate the role of 14 polymorphisms in 8 candidate genes potentially relevant for drug addiction (OPRM1, DRD2, DBH, COMT, BDNF, SLC6A4, 5HT2A, and SLC1A2) as predictors for detoxification outcome of MOH patients at 2 months of follow-up.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11579/69711
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