We report the synthesis of a polycyclic dicationic phthalocyanine through N-functionalization of the internal core with an olefin (C=C) and compared with its porphyrin analogues. Potential application of this new class of molecules as G-quadruplex (G4)-targeting ligand has been investigated by computational point of view, showing encouraging results with respect to the current benchmarks.
A Phthalocyanine with an Olefin at Its Center as Potential G‐Quadruplex Ligand
Petroselli, Manuel
Primo
Writing – Original Draft Preparation
2022-01-01
Abstract
We report the synthesis of a polycyclic dicationic phthalocyanine through N-functionalization of the internal core with an olefin (C=C) and compared with its porphyrin analogues. Potential application of this new class of molecules as G-quadruplex (G4)-targeting ligand has been investigated by computational point of view, showing encouraging results with respect to the current benchmarks.File in questo prodotto:
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