The aim of this study was to evaluate the effect of two N-BPs, neridronate (NER) and zoledronate (ZOL), low concentration (10 nM-10 µM) stimulation on keratinocyte cellular behavior in an in vitro wound healing model. At the tested concentrations, both NER and ZOL stimulated keratinocytes proliferation. Moreover N-BPs stimulated in vitro wound healing ability.
Low concentration amino-bisphosphonates stimulate human keratinocyte proliferation and in vitro wound healing
MIGLIARIO, MARIO;Rizzi M;INVERNIZZI, MARCO;CISARI, Carlo;RENO', Filippo;ROCCHETTI, Vincenzo
2012-01-01
Abstract
The aim of this study was to evaluate the effect of two N-BPs, neridronate (NER) and zoledronate (ZOL), low concentration (10 nM-10 µM) stimulation on keratinocyte cellular behavior in an in vitro wound healing model. At the tested concentrations, both NER and ZOL stimulated keratinocytes proliferation. Moreover N-BPs stimulated in vitro wound healing ability.File in questo prodotto:
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