Several biological and clinical features have been recognized in mantle cell lymphoma (MCL). In recent years, the minimal residual disease (MRD) has been extensively investigated and is now considered as one of the strongest clinical predictors in this lymphoma. This article reviews methods used for the assessment of MRD in MCL and discusses their strengths and weaknesses. In addition, it examines the MRD contribution to the biology knowledge of MCL and the development of effective strategies for its management, including the possibility of personalized treatment based on MRD response.
Minimal Residual Disease in Mantle Cell Lymphoma: Methods and Clinical Significance
Ladetto M.
;
2020-01-01
Abstract
Several biological and clinical features have been recognized in mantle cell lymphoma (MCL). In recent years, the minimal residual disease (MRD) has been extensively investigated and is now considered as one of the strongest clinical predictors in this lymphoma. This article reviews methods used for the assessment of MRD in MCL and discusses their strengths and weaknesses. In addition, it examines the MRD contribution to the biology knowledge of MCL and the development of effective strategies for its management, including the possibility of personalized treatment based on MRD response.| File | Dimensione | Formato | |
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first-page-pdf.pdf
file disponibile solo agli amministratori
Tipologia:
Altro materiale allegato
Licenza:
DRM non definito
Dimensione
89.99 kB
Formato
Adobe PDF
|
89.99 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
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