IRIS
RIZZI, Menico
 Distribuzione geografica
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Continente #
EU - Europa 2.607
NA - Nord America 2.339
AS - Asia 539
Continente sconosciuto - Info sul continente non disponibili 8
SA - Sud America 4
AF - Africa 1
OC - Oceania 1
Totale 5.499
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Nazione #
US - Stati Uniti d'America 2.322
IE - Irlanda 803
SE - Svezia 425
DE - Germania 401
IT - Italia 383
UA - Ucraina 286
CN - Cina 213
FI - Finlandia 155
SG - Singapore 133
IN - India 80
HK - Hong Kong 70
CZ - Repubblica Ceca 50
GB - Regno Unito 28
FR - Francia 18
TR - Turchia 18
BE - Belgio 16
CA - Canada 15
CH - Svizzera 11
IR - Iran 11
EU - Europa 8
NL - Olanda 7
KR - Corea 5
PL - Polonia 5
ES - Italia 4
RU - Federazione Russa 4
AT - Austria 3
CL - Cile 3
RO - Romania 3
DK - Danimarca 2
JP - Giappone 2
LT - Lituania 2
TH - Thailandia 2
VN - Vietnam 2
BR - Brasile 1
IL - Israele 1
KZ - Kazakistan 1
MA - Marocco 1
MX - Messico 1
NZ - Nuova Zelanda 1
PA - Panama 1
PT - Portogallo 1
UZ - Uzbekistan 1
Totale 5.499
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Città #
Dublin 803
Jacksonville 565
Dearborn 266
Chandler 223
Wilmington 125
Piemonte 119
Ann Arbor 113
Lawrence 99
Princeton 99
Singapore 94
Beijing 91
San Mateo 82
Hong Kong 68
Bremen 60
Brno 50
Ashburn 48
Andover 45
Boardman 31
Houston 25
Novara 25
Milan 24
Munich 19
Guangzhou 18
Nanjing 18
Woodbridge 18
Vercelli 17
Brussels 16
Kunming 16
Strasbourg 15
Toronto 15
Kocaeli 14
Turin 13
Hefei 11
Helsinki 11
Philadelphia 11
Norwalk 9
Santa Clara 9
Seattle 9
Torino 9
Monmouth Junction 8
Nanchang 8
Ardabil 7
Bologna 6
Cambridge 6
Jinan 6
Lugano 6
Casalecchio Di Reno 5
Leawood 5
Palermo 5
Poznan 5
Ankara 4
Ansbach 4
Bari 4
Cellio 4
Chongqing 4
Fairfield 4
Fort Worth 4
Fuzhou 4
Genoa 4
Mülheim 4
Pavia 4
Shenyang 4
Zurich 4
Augusta 3
Didcot 3
Grafing 3
Hangzhou 3
Horia 3
Los Angeles 3
Palo Alto 3
Pisa 3
Redwood City 3
Shaoxing 3
Shenzhen 3
Torrazza Piemonte 3
Vienna 3
Wuhan 3
Amsterdam 2
Bengaluru 2
Boadilla del Monte 2
Bonn 2
Cassano Magnago 2
Ceppaloni 2
Chengdu 2
Copenhagen 2
Dong Ket 2
Grafenhausen 2
Haeundae-gu 2
Kaunas 2
Mainz 2
Moncalieri 2
Muggia 2
Nanning 2
Piancogno 2
Quzhou 2
Rome 2
Saluzzo 2
San Diego 2
Sandrigo 2
Seongbuk-gu 2
Totale 3.510
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Nome #
Crystal structure of Mycobacterium tuberculosis O6-methylguanine-DNA methyltransferase protein clusters assembled onto damaged DNA 99
Absolute structure and structure-function relationships of 4R,2’R and 4S,2’S Pidotimod 83
Biochemical and structural investigations on phosphoribosylpyrophosphate synthetase from Mycobacterium smegmatis 82
Crystal structure of human nicotinic acid phosphoribosyltransferase 81
Hit discovery of Mycobacterium tuberculosis inosine 5′-monophosphate dehydrogenase, GuaB2, inhibitors 80
Biochemical and Structural Studies of the Mycobacterium tuberculosis O6-Methylguanine Methyltransferase and Mutated Variants 80
A nicotinamide phosphoribosyltransferase–GAPDH interaction sustains the stress-induced NMN/NAD+ salvage pathway in the nucleus 80
A NOVEL DEAMIDO-NAD BINDING SITE REVEALED BY THE TRAPPED NAD-ADENYLATE INTERMEDIATE IN THE NAD SYNTHETASE STRUCTURE 78
Mycobacterium tuberculosis UvrB forms dimers in solution and interacts with UvrA in the absence of ligands 78
Interdomain interactions rearrangements control the reaction steps of a thermostable DNA alkyltransferase 78
Structure of nicotinamide mononucleotide adenylyltransferase: a key enzyme in NAD(+) biosynthesis 74
Heterologous expression, purification, and enzymatic activity of Mycobacterium tuberculosis NAD(+) synthetase 73
Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein 73
New structures of allosteric proteins reveal remarkable 71
Human alpha-thrombin inhibition by the active site titrant Nalpha-(N,N-dimethylcarbamoyl)-alpha-azalysine-p-nitrophenyl-ester: a comparative kinetic and x-ray crystallographic study 69
Mycobacterium tuberculosis Molecular Determinants of Infection, Survival Strategies, and Vulnerable Targets 69
Functional characterization of the Mycobacterium tuberculosis zinc metallopeptidase Zmp1 and identification of potential substrates. 68
Design, synthesis, SAR and biological investigation of 3-(carboxymethyl)rhodanine and aminothiazole inhibitors of Mycobacterium tuberculosis Zmp1 68
Progress in the Field of Aldehyde Dehydrogenase Inhibitors: Novel Imidazo[1,2-a]pyridines against the 1A Family 68
Crystal structure of human aldehyde dehydrogenase 1A3 complexed with NAD+ and retinoic acid 63
European education corridors: opportunity for academic solidarity 62
Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment 62
Crystal structure of the Mycobacterium tuberculosis phosphate binding protein PstS3 61
Sulfide recognition in Lucina pectinata hemoglobin I: a crystallographic study 60
Crystal structure of D-amino acis oxidase: a case of active site mirror-image convergent evolution with flavocytochrome b2 60
Cyanide binding to Lucina pectinata hemoglobin I and to sperm whale myoglobin: An x-ray crystallographic study RID D-5386-2011 60
Functional modulation by lactate of myoglobin. A monomeric allosteric hemoprotein 59
Crystal structure-based selective targeting of the pyridoxal 5'-phosphate dependent enzyme kynurenine aminotransferase II for cognitive enhancement 59
Extracellular nicotinamide phosphoribosyltransferase (NAMPT) promotes M2 macrophage polarization in chronic lymphocytic leukemia. 59
Allosteric regulation of Bacillus subtilis NAD kinase by quinolinic acid 59
Targeting Genome Integrity in Mycobacterium Tuberculosis: From Nucleotide Synthesis to DNA Replication and Repair 59
Crystal structure of Escherichia coli pyruvate kinase type-I: molecular basis of the allosteric transition 58
A novel fold revealed by Mycobacterium tuberculosis NAD kinase, a key allosteric enzyme in NADP biosynthesis 58
Biochemical characterization of Plasmodium falciparum CDPK4 and Anopheles gambiae TDO: two antimalarial targets 58
Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis 58
Binding of non-catalytic ATP to human hexokinase I highlights the structural components for enzyme-membrane association control RID D-5386-2011 57
Every OGT is illuminated … By fluorescent and synchrotron lights 57
Crystal structure of Haemophilus influenzae 3-isopropylmalate dehydrogenase (LeuB) in complex with the inhibitor O-isobutenyl oxalylhydroxamate 57
Curcumin-based-fluorescent probes targeting ALDH1A3 as a promising tool for glioblastoma precision surgery and early diagnosis 56
Structure of the sulfide-reactive hemoglobin from the clam Lucina pectinata crystallographic analysis at 1.5 Å resolution 56
Structural biology of enzymes involved in NAD and molybdenum cofactor biosynthesis 56
Biochemical and structural investigations on kynurenine aminotransferase II: an example of conformation-driven species-specific inhibition? 56
The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis 56
Study of Anopheles gambiae 3-hydroxykynurenine transaminase activity and inhibition by LC-MS/MS method 56
STRUCTURE DETERMINATION OF TWO PLASMA PROTEINS: TRANSTHYRETIN AND RETINOL BINDING PROTEIN 55
Crystal structure of human kynurenine aminotransferase II, a drug target for the treatment of schizophrenia 54
Crystal structure of the Anopheles gambiae 3-hydroxykynurenine transaminase 54
Crystal structure of human kynurenine aminotransferase I 54
Essential but not vulnerable: indazole sulfonamides targeting inosine monophosphate dehydrogenase as potential leads against Mycobacterium tuberculosis 54
A covalent modification of NADP(+) revealed by the atomic resolution structure of FprA, a Mycobacterium tuberculosis oxidoreductase RID D-7098-2011 53
Biochemical mechanisms leading to tryptophan 2,3-dioxygenase activation 52
The high-resolution crystal structure of periplasmic Haemophilus influenzae NAD nucleotidase reveals a novel enzymatic function of human CD73 related to NAD metabolism 52
Discovery of the first potent and selective Mycobacterium tuberculosis Zmp1 inhibitor 52
Extracellular NAD+ enhances PARP-dependent DNA repair capacity independently of CD73 activity 52
Identification and biochemical characterization of the Anopheles gambiae 3-hydroxykynurenine transaminase 52
Targeting NAD-dependent dehydrogenases in drug discovery against infectious diseases and cancer 52
Expanding benzoxazole based inosine 5'-monophosphate dehydrogenase (IMPDH) inhibitor structure-activity as potential anti-tuberculosis agents 51
Curiosity to kill the KAT (kynurenine aminotransferase): structural insights into brain kynurenic acid synthesis 50
Synthesis and Structure–Activity relationship of 1-(5-isoquinolinesulfonyl)piperazine analogues as inhibitors of Mycobacterium tuberculosis IMPDH 50
Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis 49
CRYSTAL STRUCTURE OF NH3-DEPENDENT NAD SYNTHETASE FROM BACILLUS SUBTILIS 49
Expression, purification and characterisation of haemophilus influenzae 3-isopropylmalate dehydrogenase (LeuB) 48
Human kynurenine aminotransferase II--reactivity with substrates and inhibitors 47
Analysis of the wild-type and mutant genes encoding the enzyme mosquito kynurenine monooxygenase of the yellow fever mosquito Aedes aegypti 47
Signalling Inhibitors Against Mycobacterium tuberculosis - Early Days of a New Therapeutic Concept in Tuberculosis 46
The synthesis of kynurenic acid in mammals: an updated kynurenine aminotransferase structural KATalogue 46
Structure of Thermococcus litoralis trans-3-hydroxy-L-proline dehydratase in the free and substrate-complexed form 46
The crystal structure of human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis 45
+Mycobacterium tuberculosis Phosphoribosylpyrophosphate Synthetase: Biochemical Features of a Crucial Enzyme for Mycobacterial Cell Wall Biosynthesis 45
A specific inhibitor of ALDH1A3 regulates retinoic acid biosynthesis in glioma stem cells 45
Target Flexibility: An Emerging Consideration in Drug Discovery and Design RID A-8008-2011 44
Old and new targets for innovative antimalarial compounds: the different strategies of the Italian Malaria Network 44
The Potent Antiplasmodial Calmodulin-Antagonist Trifluoperazine Inhibits Plasmodium Falciparum Calcium-Dependent Protein Kinase 4. 44
Structures of citrate synthase and malate dehydrogenase ofMycobacterium tuberculosis 44
Human alpha-thrombin inhibition by the highly selective compounds: N-ethoxycarbonyl-D-Phe-Pro-alpha-azalysinep-nitrophenylester,N-carbobenzoxy-Pro alpha-azalysine-p-nitrophenyl-ester and Nalpha-(N,N-dimethylcarbamoyl)-?-azalysine-p-nitrophenyl-ester: a kinetic, thermodynamic and x-ray crystallographic study 44
The INN global nomenclature of biological medicines: A continuous challenge 44
The ATP-dependent nucleosome remodeling factor ISWI physically interacts with Poly (ADP-ribose)polymerase-1 43
Purification and biochemical characterization of a recombinant Anopheles gambiae tryptophan 2,3-dioxygenase expressed in Escherichia coli 41
The structure of Rigidoporus lignosus laccase containing a full complement of copper ions, reveals an asymmetrical arrangement for the T3 copper pair 41
GDP-4-keto-6-deoxy-D-mannose epimerase/reductase from Escherichia coli, a key enzyme in the biosynthesis of GDP-L-fucose, displays the structural characteristics of the RED protein homology superfamily 41
A selective competitive inhibitor of aldehyde dehydrogenase 1A3 hinders cancer cell growth, invasiveness and stemness in vitro 41
The integration of AlphaFold-predicted and crystal structures of human trans-3-hydroxy-l-proline dehydratase reveals a regulatory catalytic mechanism 40
The biological and structural characterization of Mycobacterium tuberculosis UvrA provides novel insights into its mechanism of action RID D-2548-2009 RID F-6175-2011 40
Structural investigations on Zmp1 from Mycobacterium tuberculosis, a Zn-metalloprotease that prevents inflammasome activation and phagosome maturation 40
Structural investigations on M. tuberculosis proteins involved in DNA repair 40
Crystal structures of Aedes aegypti alanine glyoxylate aminotransferase 40
Mycobacterium tuberculosis UvrD1 and UvrA Proteins Suppress DNA Strand Exchange Promoted by Cognate and Noncognate RecA Proteins 40
X-ray crystallography, mass spectrometry and single crystal microspectrophotometry: A multidisciplinary characterization of catechol 1,2 dioxygenase 39
Structure of Thermococcus litoralis Δ1-pyrroline-2-carboxylate reductase in complex with NADH and L-proline 39
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase, new insights into an ancient enzyme 38
Structure of human NMN adenylyltransferase - A key nuclear enzyme for NAD homeostasis 38
The MTCY428.08 gene of Mycobacterium tuberculosis codes for NAD synthetase 37
Enhancement of the HIV-1 inhibitory activity of RANTES by modification of the N-terminal region: dissociation from CCR5 activation 36
Crystal Structure of Mycobacterium tuberculosis Zinc-dependent Metalloprotease-1 (Zmp1), a Metalloprotease Involved in Pathogenicity RID D-2548-2009 36
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Aryloxyaryl Moiety 35
Biochemical characterization of Mycobacterium tuberculosis dihydroorotate dehydrogenase and identification of a selective inhibitor 35
The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology 35
Determination of H2S solubility via the reaction with ferric hemoglobin I from the bivalve mollusc Lucina pectinata 32
Expression, purification and characterization of UvrD2 helicase from Mycobacterium tuberculosis 31
Structural determinants of CCR5 recognition and HIV-1 blockade in RANTES RID D-1688-2011 31
Totale 5.387
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Categoria #
all - tutte 31.553
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 31.553
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020998 0 0 0 0 167 158 234 65 127 115 128 4
2020/2021737 103 3 101 18 97 15 103 9 107 42 115 24
2021/2022698 38 40 130 54 27 4 56 8 55 16 110 160
2022/20231.758 128 75 110 41 150 183 39 103 835 14 48 32
2023/2024529 44 52 53 14 98 5 83 11 3 20 41 105
2024/2025198 54 10 94 22 18 0 0 0 0 0 0 0
Totale 5.592