IRIS
RIZZI, Menico
 Distribuzione geografica
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Continente #
EU - Europa 4.279
NA - Nord America 3.910
AS - Asia 2.653
SA - Sud America 412
AF - Africa 69
Continente sconosciuto - Info sul continente non disponibili 8
OC - Oceania 2
Totale 11.333
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Nazione #
US - Stati Uniti d'America 3.813
RU - Federazione Russa 1.017
SG - Singapore 907
IE - Irlanda 804
CN - Cina 626
DE - Germania 530
IT - Italia 523
SE - Svezia 437
VN - Vietnam 397
HK - Hong Kong 355
BR - Brasile 314
UA - Ucraina 302
FR - Francia 170
FI - Finlandia 168
IN - India 124
GB - Regno Unito 121
CA - Canada 58
CZ - Repubblica Ceca 52
KR - Corea 41
AR - Argentina 35
PL - Polonia 33
TR - Turchia 28
BD - Bangladesh 27
MX - Messico 25
JP - Giappone 23
ES - Italia 22
BJ - Benin 21
AT - Austria 20
ZA - Sudafrica 19
BE - Belgio 17
ID - Indonesia 17
NL - Olanda 17
TH - Thailandia 17
EC - Ecuador 15
IQ - Iraq 15
VE - Venezuela 13
CH - Svizzera 12
IR - Iran 11
CL - Cile 10
CO - Colombia 10
MA - Marocco 10
SA - Arabia Saudita 9
UZ - Uzbekistan 9
EU - Europa 8
PE - Perù 7
EE - Estonia 6
PH - Filippine 6
RO - Romania 6
AE - Emirati Arabi Uniti 5
LT - Lituania 5
PK - Pakistan 5
PY - Paraguay 5
TN - Tunisia 5
TW - Taiwan 5
DK - Danimarca 4
AZ - Azerbaigian 3
DZ - Algeria 3
EG - Egitto 3
IL - Israele 3
JM - Giamaica 3
JO - Giordania 3
MD - Moldavia 3
MY - Malesia 3
BH - Bahrain 2
BO - Bolivia 2
DO - Repubblica Dominicana 2
KE - Kenya 2
KZ - Kazakistan 2
LB - Libano 2
MN - Mongolia 2
NG - Nigeria 2
NP - Nepal 2
PS - Palestinian Territory 2
PT - Portogallo 2
SN - Senegal 2
SV - El Salvador 2
AU - Australia 1
BB - Barbados 1
BG - Bulgaria 1
BS - Bahamas 1
CR - Costa Rica 1
CY - Cipro 1
ET - Etiopia 1
GD - Grenada 1
GR - Grecia 1
HR - Croazia 1
IS - Islanda 1
LU - Lussemburgo 1
LY - Libia 1
MK - Macedonia 1
NI - Nicaragua 1
NZ - Nuova Zelanda 1
PA - Panama 1
PR - Porto Rico 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
SY - Repubblica araba siriana 1
UY - Uruguay 1
Totale 11.333
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Città #
Dublin 804
Jacksonville 568
San Jose 354
Hong Kong 348
Singapore 283
Dearborn 266
Ashburn 242
Beijing 223
Chandler 223
Moscow 157
Wilmington 125
Ho Chi Minh City 124
Piemonte 119
Ann Arbor 113
Los Angeles 108
Lauterbourg 104
Lawrence 99
Princeton 99
Hanoi 98
Council Bluffs 83
San Mateo 82
Buffalo 67
Munich 65
New York 64
Bremen 60
Novara 53
Brno 50
Andover 45
Orem 43
Milan 39
São Paulo 39
Santa Clara 36
Boardman 31
Houston 31
Seoul 30
Frankfurt am Main 29
Guangzhou 27
The Dalles 25
Dallas 24
Warsaw 24
Toronto 23
Cotonou 21
London 21
Turin 21
Brooklyn 19
Chennai 19
Vercelli 19
Nanjing 18
Phoenix 18
Tianjin 18
Woodbridge 18
Brussels 17
Montreal 17
Redondo Beach 17
Tokyo 17
Helsinki 16
Kunming 16
Haiphong 15
Strasbourg 15
Chicago 14
Denver 14
Kocaeli 14
Manchester 14
Mexico City 14
Nuremberg 14
Da Nang 13
Poplar 13
Assago 12
Hangzhou 12
Johannesburg 12
Philadelphia 12
Rio de Janeiro 12
Seattle 12
Stockholm 12
Hefei 11
Ankara 10
Atlanta 10
Carmagnola 10
Guayaquil 10
St Louis 10
Amsterdam 9
Columbus 9
Jakarta 9
Norwalk 9
Torino 9
Barnet 8
Bexley 8
Las Vegas 8
Monmouth Junction 8
Mumbai 8
Nanchang 8
Rome 8
San Francisco 8
Shenzhen 8
Turku 8
Vienna 8
Ardabil 7
Bangkok 7
Boston 7
Buenos Aires 7
Totale 6.165
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Nome #
Structural investigations on Zmp1 from Mycobacterium tuberculosis, a Zn-metalloprotease that prevents inflammasome activation and phagosome maturation 212
Crystal structure of Mycobacterium tuberculosis O6-methylguanine-DNA methyltransferase protein clusters assembled onto damaged DNA 174
A nicotinamide phosphoribosyltransferase–GAPDH interaction sustains the stress-induced NMN/NAD+ salvage pathway in the nucleus 161
Curcumin-based-fluorescent probes targeting ALDH1A3 as a promising tool for glioblastoma precision surgery and early diagnosis 160
Biochemical and structural investigations on phosphoribosylpyrophosphate synthetase from Mycobacterium smegmatis 150
Crystal structure of human nicotinic acid phosphoribosyltransferase 148
Progress in the Field of Aldehyde Dehydrogenase Inhibitors: Novel Imidazo[1,2-a]pyridines against the 1A Family 144
Absolute structure and structure-function relationships of 4R,2’R and 4S,2’S Pidotimod 141
Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein 140
Hit discovery of Mycobacterium tuberculosis inosine 5′-monophosphate dehydrogenase, GuaB2, inhibitors 139
Interdomain interactions rearrangements control the reaction steps of a thermostable DNA alkyltransferase 137
Mechanistic understanding of UvrA damage detection and lesion hand-off to UvrB in Nucleotide Excision Repair 136
Extracellular nicotinamide phosphoribosyltransferase (NAMPT) promotes M2 macrophage polarization in chronic lymphocytic leukemia. 133
A specific inhibitor of ALDH1A3 regulates retinoic acid biosynthesis in glioma stem cells 131
Targeting NAD-dependent dehydrogenases in drug discovery against infectious diseases and cancer 129
Biochemical characterization of Mycobacterium tuberculosis dihydroorotate dehydrogenase and identification of a selective inhibitor 128
An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent 128
Biochemical and Structural Studies of the Mycobacterium tuberculosis O6-Methylguanine Methyltransferase and Mutated Variants 128
A NOVEL DEAMIDO-NAD BINDING SITE REVEALED BY THE TRAPPED NAD-ADENYLATE INTERMEDIATE IN THE NAD SYNTHETASE STRUCTURE 126
Targeting Genome Integrity in Mycobacterium Tuberculosis: From Nucleotide Synthesis to DNA Replication and Repair 124
Biochemical and structural investigations on kynurenine aminotransferase II: an example of conformation-driven species-specific inhibition? 122
A selective competitive inhibitor of aldehyde dehydrogenase 1A3 hinders cancer cell growth, invasiveness and stemness in vitro 122
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Aryloxyaryl Moiety 121
Crystal structure-based selective targeting of the pyridoxal 5'-phosphate dependent enzyme kynurenine aminotransferase II for cognitive enhancement 121
Binding of non-catalytic ATP to human hexokinase I highlights the structural components for enzyme-membrane association control RID D-5386-2011 120
Structure of Thermococcus litoralis trans-3-hydroxy-L-proline dehydratase in the free and substrate-complexed form 120
Crystal structure of human aldehyde dehydrogenase 1A3 complexed with NAD+ and retinoic acid 119
Crystal structure of Haemophilus influenzae 3-isopropylmalate dehydrogenase (LeuB) in complex with the inhibitor O-isobutenyl oxalylhydroxamate 117
AI is a viable alternative to high throughput screening: a 318-target study 116
Biochemical and structural analysis of a cytosolic sulfotransferase of the malaria vector Anopheles gambiae overexpressed in the reproductive tissues 116
European education corridors: opportunity for academic solidarity 115
A novel fold revealed by Mycobacterium tuberculosis NAD kinase, a key allosteric enzyme in NADP biosynthesis 114
Biochemical characterization of Plasmodium falciparum CDPK4 and Anopheles gambiae TDO: two antimalarial targets 113
Design, synthesis, SAR and biological investigation of 3-(carboxymethyl)rhodanine and aminothiazole inhibitors of Mycobacterium tuberculosis Zmp1 113
Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment 113
Mycobacterium tuberculosis UvrB forms dimers in solution and interacts with UvrA in the absence of ligands 112
Every OGT is illuminated â ¦ By fluorescent and synchrotron lights 111
Extracellular NAD+ enhances PARP-dependent DNA repair capacity independently of CD73 activity 110
Functional characterization of the Mycobacterium tuberculosis zinc metallopeptidase Zmp1 and identification of potential substrates. 109
Crystal structure of human kynurenine aminotransferase II, a drug target for the treatment of schizophrenia 109
Study of Anopheles gambiae 3-hydroxykynurenine transaminase activity and inhibition by LC-MS/MS method 108
Allosteric regulation of Bacillus subtilis NAD kinase by quinolinic acid 107
Crystal structure of the Mycobacterium tuberculosis phosphate binding protein PstS3 106
Heterologous expression, purification, and enzymatic activity of Mycobacterium tuberculosis NAD(+) synthetase 105
The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis 105
Mycobacterium tuberculosis Molecular Determinants of Infection, Survival Strategies, and Vulnerable Targets 105
Crystal structure of human kynurenine aminotransferase I 104
Synthesis and Structure–Activity relationship of 1-(5-isoquinolinesulfonyl)piperazine analogues as inhibitors of Mycobacterium tuberculosis IMPDH 104
Human alpha-thrombin inhibition by the active site titrant Nalpha-(N,N-dimethylcarbamoyl)-alpha-azalysine-p-nitrophenyl-ester: a comparative kinetic and x-ray crystallographic study 103
Structure of nicotinamide mononucleotide adenylyltransferase: a key enzyme in NAD(+) biosynthesis 103
Crystal Structure of Mycobacterium tuberculosis Zinc-dependent Metalloprotease-1 (Zmp1), a Metalloprotease Involved in Pathogenicity RID D-2548-2009 103
Crystal structure of the Anopheles gambiae 3-hydroxykynurenine transaminase 102
Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis 102
A covalent modification of NADP(+) revealed by the atomic resolution structure of FprA, a Mycobacterium tuberculosis oxidoreductase RID D-7098-2011 101
Cyanide binding to Lucina pectinata hemoglobin I and to sperm whale myoglobin: An x-ray crystallographic study RID D-5386-2011 101
Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis 99
Curiosity to kill the KAT (kynurenine aminotransferase): structural insights into brain kynurenic acid synthesis 98
The Potent Antiplasmodial Calmodulin-Antagonist Trifluoperazine Inhibits Plasmodium Falciparum Calcium-Dependent Protein Kinase 4. 98
Discovery of the first potent and selective Mycobacterium tuberculosis Zmp1 inhibitor 98
Essential but not vulnerable: indazole sulfonamides targeting inosine monophosphate dehydrogenase as potential leads against Mycobacterium tuberculosis 96
Expression, purification and characterisation of haemophilus influenzae 3-isopropylmalate dehydrogenase (LeuB) 94
Functional modulation by lactate of myoglobin. A monomeric allosteric hemoprotein 93
Crystal structure of Escherichia coli pyruvate kinase type-I: molecular basis of the allosteric transition 93
New structures of allosteric proteins reveal remarkable 93
Biochemical mechanisms leading to tryptophan 2,3-dioxygenase activation 93
The integration of AlphaFold-predicted and crystal structures of human trans-3-hydroxy-l-proline dehydratase reveals a regulatory catalytic mechanism 92
Crystal structure of D-amino acis oxidase: a case of active site mirror-image convergent evolution with flavocytochrome b2 92
+Mycobacterium tuberculosis Phosphoribosylpyrophosphate Synthetase: Biochemical Features of a Crucial Enzyme for Mycobacterial Cell Wall Biosynthesis 92
The synthesis of kynurenic acid in mammals: an updated kynurenine aminotransferase structural KATalogue 92
Cryo-EM-based structural investigation of Mycobacterium tuberculosis Nucleotide Excision Repair 91
Expanding benzoxazole based inosine 5'-monophosphate dehydrogenase (IMPDH) inhibitor structure-activity as potential anti-tuberculosis agents 91
Structure of the sulfide-reactive hemoglobin from the clam Lucina pectinata crystallographic analysis at 1.5 Å resolution 90
Human kynurenine aminotransferase II--reactivity with substrates and inhibitors 90
Cryo-EM-based structural investigation of Mycobacterium tuberculosis Nucleotide Excision Repair 89
Crystal structures of Aedes aegypti alanine glyoxylate aminotransferase 89
The structure of Rigidoporus lignosus laccase containing a full complement of copper ions, reveals an asymmetrical arrangement for the T3 copper pair 89
Analysis of the wild-type and mutant genes encoding the enzyme mosquito kynurenine monooxygenase of the yellow fever mosquito Aedes aegypti 89
STRUCTURE DETERMINATION OF TWO PLASMA PROTEINS: TRANSTHYRETIN AND RETINOL BINDING PROTEIN 88
The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology 88
Sulfide recognition in Lucina pectinata hemoglobin I: a crystallographic study 87
The crystal structure of human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis 87
The high-resolution crystal structure of periplasmic Haemophilus influenzae NAD nucleotidase reveals a novel enzymatic function of human CD73 related to NAD metabolism 87
Identification and biochemical characterization of the Anopheles gambiae 3-hydroxykynurenine transaminase 86
Structural biology of enzymes involved in NAD and molybdenum cofactor biosynthesis 85
CRYSTAL STRUCTURE OF NH3-DEPENDENT NAD SYNTHETASE FROM BACILLUS SUBTILIS 84
Purification and biochemical characterization of a recombinant Anopheles gambiae tryptophan 2,3-dioxygenase expressed in Escherichia coli 82
Structure of human NMN adenylyltransferase - A key nuclear enzyme for NAD homeostasis 80
Old and new targets for innovative antimalarial compounds: the different strategies of the Italian Malaria Network 79
Structure of Thermococcus litoralis Δ1-pyrroline-2-carboxylate reductase in complex with NADH and L-proline 79
Human alpha-thrombin inhibition by the highly selective compounds: N-ethoxycarbonyl-D-Phe-Pro-alpha-azalysinep-nitrophenylester,N-carbobenzoxy-Pro alpha-azalysine-p-nitrophenyl-ester and Nalpha-(N,N-dimethylcarbamoyl)-?-azalysine-p-nitrophenyl-ester: a kinetic, thermodynamic and x-ray crystallographic study 79
Nucleotide Excision Repair in Mycobacterium tuberculosis: a Cryo-EM snapshot of the damage recognition process 79
Nonvertebrate oxygen carrier hemoproteins: structural bases for reactivity 78
GDP-4-keto-6-deoxy-D-mannose epimerase/reductase from Escherichia coli, a key enzyme in the biosynthesis of GDP-L-fucose, displays the structural characteristics of the RED protein homology superfamily 77
Determination of H2S solubility via the reaction with ferric hemoglobin I from the bivalve mollusc Lucina pectinata 73
The biological and structural characterization of Mycobacterium tuberculosis UvrA provides novel insights into its mechanism of action RID D-2548-2009 RID F-6175-2011 72
Structural investigations on M. tuberculosis proteins involved in DNA repair 72
Structures of citrate synthase and malate dehydrogenase ofMycobacterium tuberculosis 72
Signalling Inhibitors Against Mycobacterium tuberculosis - Early Days of a New Therapeutic Concept in Tuberculosis 72
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase, new insights into an ancient enzyme 71
The ATP-dependent nucleosome remodeling factor ISWI physically interacts with Poly (ADP-ribose)polymerase-1 71
Totale 10.610
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Categoria #
all - tutte 55.711
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 55.711
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202124 0 0 0 0 0 0 0 0 0 0 0 24
2021/2022698 38 40 130 54 27 4 56 8 55 16 110 160
2022/20231.758 128 75 110 41 150 183 39 103 835 14 48 32
2023/2024529 44 52 53 14 98 5 83 11 3 20 41 105
2024/20251.544 54 10 94 22 36 183 113 103 316 129 156 328
2025/20264.494 250 182 324 717 441 341 541 707 300 394 226 71
Totale 11.432