IRIS
RIZZI, Menico
 Distribuzione geografica
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Continente #
EU - Europa 4.299
NA - Nord America 4.270
AS - Asia 2.673
SA - Sud America 421
Continente sconosciuto - Info sul continente non disponibili 107
AF - Africa 69
OC - Oceania 2
Totale 11.841
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Nazione #
US - Stati Uniti d'America 4.158
RU - Federazione Russa 1.017
SG - Singapore 913
IE - Irlanda 804
CN - Cina 632
IT - Italia 538
DE - Germania 530
SE - Svezia 438
VN - Vietnam 397
HK - Hong Kong 358
BR - Brasile 318
UA - Ucraina 302
FR - Francia 172
FI - Finlandia 168
IN - India 125
GB - Regno Unito 121
CA - Canada 64
CZ - Repubblica Ceca 53
KR - Corea 41
AR - Argentina 36
PL - Polonia 34
BD - Bangladesh 29
TR - Turchia 28
MX - Messico 27
JP - Giappone 23
ES - Italia 22
BJ - Benin 21
AT - Austria 20
ZA - Sudafrica 19
ID - Indonesia 18
TH - Thailandia 18
BE - Belgio 17
NL - Olanda 17
EC - Ecuador 15
IQ - Iraq 15
VE - Venezuela 14
CO - Colombia 13
CH - Svizzera 12
IR - Iran 11
CL - Cile 10
MA - Marocco 10
SA - Arabia Saudita 9
UZ - Uzbekistan 9
EU - Europa 8
PE - Perù 7
EE - Estonia 6
PH - Filippine 6
RO - Romania 6
AE - Emirati Arabi Uniti 5
JM - Giamaica 5
LT - Lituania 5
PK - Pakistan 5
PY - Paraguay 5
TN - Tunisia 5
TW - Taiwan 5
DK - Danimarca 4
AZ - Azerbaigian 3
DZ - Algeria 3
EG - Egitto 3
GT - Guatemala 3
IL - Israele 3
JO - Giordania 3
MD - Moldavia 3
MY - Malesia 3
BH - Bahrain 2
BO - Bolivia 2
DO - Repubblica Dominicana 2
KE - Kenya 2
KZ - Kazakistan 2
LB - Libano 2
MN - Mongolia 2
NG - Nigeria 2
NP - Nepal 2
PR - Porto Rico 2
PS - Palestinian Territory 2
PT - Portogallo 2
SN - Senegal 2
SV - El Salvador 2
AG - Antigua e Barbuda 1
AU - Australia 1
BB - Barbados 1
BG - Bulgaria 1
BS - Bahamas 1
CR - Costa Rica 1
CY - Cipro 1
ET - Etiopia 1
GD - Grenada 1
GR - Grecia 1
HR - Croazia 1
IS - Islanda 1
LU - Lussemburgo 1
LY - Libia 1
MK - Macedonia 1
NI - Nicaragua 1
NZ - Nuova Zelanda 1
PA - Panama 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
SY - Repubblica araba siriana 1
UY - Uruguay 1
Totale 11.742
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Città #
Dublin 804
Jacksonville 572
San Jose 361
Hong Kong 351
Singapore 288
Dearborn 266
Ashburn 253
Beijing 226
Chandler 223
Council Bluffs 221
Moscow 157
Wilmington 125
Ho Chi Minh City 124
Piemonte 119
Ann Arbor 113
Los Angeles 111
Lauterbourg 104
Lawrence 99
Princeton 99
Hanoi 98
Columbus 85
San Mateo 82
Buffalo 67
Munich 65
New York 65
Bremen 60
Novara 53
Brno 50
Santa Clara 48
Andover 45
Orem 43
São Paulo 40
Milan 39
Boardman 31
Houston 31
Seoul 30
Frankfurt am Main 29
Guangzhou 27
Toronto 26
The Dalles 25
Warsaw 25
Dallas 24
Turin 22
Cotonou 21
London 21
Phoenix 21
Brooklyn 20
Chennai 19
Vercelli 19
Nanjing 18
Tianjin 18
Woodbridge 18
Brussels 17
Montreal 17
Redondo Beach 17
Tokyo 17
Chicago 16
Helsinki 16
Kunming 16
Mexico City 16
Denver 15
Haiphong 15
Philadelphia 15
Strasbourg 15
Kocaeli 14
Manchester 14
Nuremberg 14
Da Nang 13
Poplar 13
St Louis 13
Assago 12
Hangzhou 12
Johannesburg 12
Rio de Janeiro 12
Seattle 12
Stockholm 12
Atlanta 11
Hefei 11
Ankara 10
Carmagnola 10
Guayaquil 10
Naples 10
Rome 10
Amsterdam 9
Jakarta 9
Norwalk 9
Torino 9
Bangkok 8
Barnet 8
Bexley 8
Las Vegas 8
Monmouth Junction 8
Mumbai 8
Nanchang 8
Palermo 8
San Francisco 8
Shenzhen 8
Turku 8
Vienna 8
Ardabil 7
Totale 6.457
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Nome #
Structural investigations on Zmp1 from Mycobacterium tuberculosis, a Zn-metalloprotease that prevents inflammasome activation and phagosome maturation 214
Crystal structure of Mycobacterium tuberculosis O6-methylguanine-DNA methyltransferase protein clusters assembled onto damaged DNA 177
Curcumin-based-fluorescent probes targeting ALDH1A3 as a promising tool for glioblastoma precision surgery and early diagnosis 168
A nicotinamide phosphoribosyltransferase–GAPDH interaction sustains the stress-induced NMN/NAD+ salvage pathway in the nucleus 164
Biochemical and structural investigations on phosphoribosylpyrophosphate synthetase from Mycobacterium smegmatis 157
Crystal structure of human nicotinic acid phosphoribosyltransferase 150
Progress in the Field of Aldehyde Dehydrogenase Inhibitors: Novel Imidazo[1,2-a]pyridines against the 1A Family 149
Absolute structure and structure-function relationships of 4R,2’R and 4S,2’S Pidotimod 144
Mechanistic understanding of UvrA damage detection and lesion hand-off to UvrB in Nucleotide Excision Repair 143
Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein 142
Hit discovery of Mycobacterium tuberculosis inosine 5′-monophosphate dehydrogenase, GuaB2, inhibitors 142
Interdomain interactions rearrangements control the reaction steps of a thermostable DNA alkyltransferase 142
A specific inhibitor of ALDH1A3 regulates retinoic acid biosynthesis in glioma stem cells 140
Targeting NAD-dependent dehydrogenases in drug discovery against infectious diseases and cancer 137
Extracellular nicotinamide phosphoribosyltransferase (NAMPT) promotes M2 macrophage polarization in chronic lymphocytic leukemia. 135
Biochemical characterization of Mycobacterium tuberculosis dihydroorotate dehydrogenase and identification of a selective inhibitor 132
An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent 132
Targeting Genome Integrity in Mycobacterium Tuberculosis: From Nucleotide Synthesis to DNA Replication and Repair 132
Biochemical and Structural Studies of the Mycobacterium tuberculosis O6-Methylguanine Methyltransferase and Mutated Variants 131
A NOVEL DEAMIDO-NAD BINDING SITE REVEALED BY THE TRAPPED NAD-ADENYLATE INTERMEDIATE IN THE NAD SYNTHETASE STRUCTURE 130
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Aryloxyaryl Moiety 129
A selective competitive inhibitor of aldehyde dehydrogenase 1A3 hinders cancer cell growth, invasiveness and stemness in vitro 128
Biochemical and structural investigations on kynurenine aminotransferase II: an example of conformation-driven species-specific inhibition? 125
Crystal structure-based selective targeting of the pyridoxal 5'-phosphate dependent enzyme kynurenine aminotransferase II for cognitive enhancement 125
AI is a viable alternative to high throughput screening: a 318-target study 124
Structure of Thermococcus litoralis trans-3-hydroxy-L-proline dehydratase in the free and substrate-complexed form 124
Crystal structure of human aldehyde dehydrogenase 1A3 complexed with NAD+ and retinoic acid 123
Crystal structure of Haemophilus influenzae 3-isopropylmalate dehydrogenase (LeuB) in complex with the inhibitor O-isobutenyl oxalylhydroxamate 123
Binding of non-catalytic ATP to human hexokinase I highlights the structural components for enzyme-membrane association control RID D-5386-2011 122
European education corridors: opportunity for academic solidarity 121
A novel fold revealed by Mycobacterium tuberculosis NAD kinase, a key allosteric enzyme in NADP biosynthesis 120
Biochemical and structural analysis of a cytosolic sulfotransferase of the malaria vector Anopheles gambiae overexpressed in the reproductive tissues 119
Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment 118
Biochemical characterization of Plasmodium falciparum CDPK4 and Anopheles gambiae TDO: two antimalarial targets 116
Every OGT is illuminated â ¦ By fluorescent and synchrotron lights 116
Design, synthesis, SAR and biological investigation of 3-(carboxymethyl)rhodanine and aminothiazole inhibitors of Mycobacterium tuberculosis Zmp1 116
Extracellular NAD+ enhances PARP-dependent DNA repair capacity independently of CD73 activity 114
Mycobacterium tuberculosis UvrB forms dimers in solution and interacts with UvrA in the absence of ligands 114
Crystal structure of human kynurenine aminotransferase II, a drug target for the treatment of schizophrenia 112
Crystal structure of the Mycobacterium tuberculosis phosphate binding protein PstS3 112
Functional characterization of the Mycobacterium tuberculosis zinc metallopeptidase Zmp1 and identification of potential substrates. 111
Study of Anopheles gambiae 3-hydroxykynurenine transaminase activity and inhibition by LC-MS/MS method 110
The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis 109
Mycobacterium tuberculosis Molecular Determinants of Infection, Survival Strategies, and Vulnerable Targets 109
Allosteric regulation of Bacillus subtilis NAD kinase by quinolinic acid 109
Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis 109
Heterologous expression, purification, and enzymatic activity of Mycobacterium tuberculosis NAD(+) synthetase 108
Crystal Structure of Mycobacterium tuberculosis Zinc-dependent Metalloprotease-1 (Zmp1), a Metalloprotease Involved in Pathogenicity RID D-2548-2009 108
Crystal structure of human kynurenine aminotransferase I 107
Human alpha-thrombin inhibition by the active site titrant Nalpha-(N,N-dimethylcarbamoyl)-alpha-azalysine-p-nitrophenyl-ester: a comparative kinetic and x-ray crystallographic study 106
Synthesis and Structure–Activity relationship of 1-(5-isoquinolinesulfonyl)piperazine analogues as inhibitors of Mycobacterium tuberculosis IMPDH 106
Crystal structure of the Anopheles gambiae 3-hydroxykynurenine transaminase 105
A covalent modification of NADP(+) revealed by the atomic resolution structure of FprA, a Mycobacterium tuberculosis oxidoreductase RID D-7098-2011 105
Structure of nicotinamide mononucleotide adenylyltransferase: a key enzyme in NAD(+) biosynthesis 104
Cyanide binding to Lucina pectinata hemoglobin I and to sperm whale myoglobin: An x-ray crystallographic study RID D-5386-2011 103
Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis 102
Curiosity to kill the KAT (kynurenine aminotransferase): structural insights into brain kynurenic acid synthesis 101
The Potent Antiplasmodial Calmodulin-Antagonist Trifluoperazine Inhibits Plasmodium Falciparum Calcium-Dependent Protein Kinase 4. 101
Discovery of the first potent and selective Mycobacterium tuberculosis Zmp1 inhibitor 101
Cryo-EM-based structural investigation of Mycobacterium tuberculosis Nucleotide Excision Repair 98
Functional modulation by lactate of myoglobin. A monomeric allosteric hemoprotein 98
Essential but not vulnerable: indazole sulfonamides targeting inosine monophosphate dehydrogenase as potential leads against Mycobacterium tuberculosis 98
Expression, purification and characterisation of haemophilus influenzae 3-isopropylmalate dehydrogenase (LeuB) 96
The synthesis of kynurenic acid in mammals: an updated kynurenine aminotransferase structural KATalogue 96
The integration of AlphaFold-predicted and crystal structures of human trans-3-hydroxy-l-proline dehydratase reveals a regulatory catalytic mechanism 95
Crystal structure of Escherichia coli pyruvate kinase type-I: molecular basis of the allosteric transition 95
Biochemical mechanisms leading to tryptophan 2,3-dioxygenase activation 95
+Mycobacterium tuberculosis Phosphoribosylpyrophosphate Synthetase: Biochemical Features of a Crucial Enzyme for Mycobacterial Cell Wall Biosynthesis 95
The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology 95
Structure of the sulfide-reactive hemoglobin from the clam Lucina pectinata crystallographic analysis at 1.5 Å resolution 94
New structures of allosteric proteins reveal remarkable 94
Crystal structure of D-amino acis oxidase: a case of active site mirror-image convergent evolution with flavocytochrome b2 94
Cryo-EM-based structural investigation of Mycobacterium tuberculosis Nucleotide Excision Repair 93
Human kynurenine aminotransferase II--reactivity with substrates and inhibitors 93
Expanding benzoxazole based inosine 5'-monophosphate dehydrogenase (IMPDH) inhibitor structure-activity as potential anti-tuberculosis agents 93
The crystal structure of human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis 92
Crystal structures of Aedes aegypti alanine glyoxylate aminotransferase 91
The structure of Rigidoporus lignosus laccase containing a full complement of copper ions, reveals an asymmetrical arrangement for the T3 copper pair 91
Analysis of the wild-type and mutant genes encoding the enzyme mosquito kynurenine monooxygenase of the yellow fever mosquito Aedes aegypti 91
STRUCTURE DETERMINATION OF TWO PLASMA PROTEINS: TRANSTHYRETIN AND RETINOL BINDING PROTEIN 90
Sulfide recognition in Lucina pectinata hemoglobin I: a crystallographic study 89
Structural biology of enzymes involved in NAD and molybdenum cofactor biosynthesis 89
The high-resolution crystal structure of periplasmic Haemophilus influenzae NAD nucleotidase reveals a novel enzymatic function of human CD73 related to NAD metabolism 89
Identification and biochemical characterization of the Anopheles gambiae 3-hydroxykynurenine transaminase 88
Structure of human NMN adenylyltransferase - A key nuclear enzyme for NAD homeostasis 85
CRYSTAL STRUCTURE OF NH3-DEPENDENT NAD SYNTHETASE FROM BACILLUS SUBTILIS 85
Purification and biochemical characterization of a recombinant Anopheles gambiae tryptophan 2,3-dioxygenase expressed in Escherichia coli 84
Nucleotide Excision Repair in Mycobacterium tuberculosis: a Cryo-EM snapshot of the damage recognition process 84
Structure of Thermococcus litoralis Δ1-pyrroline-2-carboxylate reductase in complex with NADH and L-proline 83
Nonvertebrate oxygen carrier hemoproteins: structural bases for reactivity 83
Old and new targets for innovative antimalarial compounds: the different strategies of the Italian Malaria Network 81
Human alpha-thrombin inhibition by the highly selective compounds: N-ethoxycarbonyl-D-Phe-Pro-alpha-azalysinep-nitrophenylester,N-carbobenzoxy-Pro alpha-azalysine-p-nitrophenyl-ester and Nalpha-(N,N-dimethylcarbamoyl)-?-azalysine-p-nitrophenyl-ester: a kinetic, thermodynamic and x-ray crystallographic study 81
GDP-4-keto-6-deoxy-D-mannose epimerase/reductase from Escherichia coli, a key enzyme in the biosynthesis of GDP-L-fucose, displays the structural characteristics of the RED protein homology superfamily 78
Determination of H2S solubility via the reaction with ferric hemoglobin I from the bivalve mollusc Lucina pectinata 77
The biological and structural characterization of Mycobacterium tuberculosis UvrA provides novel insights into its mechanism of action RID D-2548-2009 RID F-6175-2011 77
Structures of citrate synthase and malate dehydrogenase ofMycobacterium tuberculosis 76
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase, new insights into an ancient enzyme 75
Structural investigations on M. tuberculosis proteins involved in DNA repair 74
Target Flexibility: An Emerging Consideration in Drug Discovery and Design RID A-8008-2011 74
Signalling Inhibitors Against Mycobacterium tuberculosis - Early Days of a New Therapeutic Concept in Tuberculosis 74
Totale 10.979
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Categoria #
all - tutte 58.422
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 58.422
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022660 0 40 130 54 27 4 56 8 55 16 110 160
2022/20231.758 128 75 110 41 150 183 39 103 835 14 48 32
2023/2024529 44 52 53 14 98 5 83 11 3 20 41 105
2024/20251.544 54 10 94 22 36 183 113 103 316 129 156 328
2025/20264.500 250 182 324 717 441 341 541 707 300 394 226 77
2026/2027403 157 246 0 0 0 0 0 0 0 0 0 0
Totale 11.841