IRIS
RIZZI, Menico
 Distribuzione geografica
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Continente #
NA - Nord America 4.858
EU - Europa 4.368
AS - Asia 2.682
SA - Sud America 427
Continente sconosciuto - Info sul continente non disponibili 110
AF - Africa 69
OC - Oceania 2
Totale 12.516
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Nazione #
US - Stati Uniti d'America 4.701
RU - Federazione Russa 1.017
SG - Singapore 914
IE - Irlanda 804
CN - Cina 633
IT - Italia 561
DE - Germania 535
SE - Svezia 438
VN - Vietnam 397
HK - Hong Kong 359
BR - Brasile 323
UA - Ucraina 302
FR - Francia 175
FI - Finlandia 168
GB - Regno Unito 146
IN - India 125
CA - Canada 83
CZ - Repubblica Ceca 53
KR - Corea 41
AR - Argentina 36
PL - Polonia 35
BD - Bangladesh 33
MX - Messico 30
TR - Turchia 28
JP - Giappone 25
ES - Italia 23
BJ - Benin 21
AT - Austria 20
ZA - Sudafrica 19
BE - Belgio 18
ID - Indonesia 18
TH - Thailandia 18
NL - Olanda 17
EC - Ecuador 15
IQ - Iraq 15
VE - Venezuela 15
CO - Colombia 13
CH - Svizzera 12
EE - Estonia 11
IR - Iran 11
CL - Cile 10
MA - Marocco 10
LT - Lituania 9
SA - Arabia Saudita 9
UZ - Uzbekistan 9
CR - Costa Rica 8
EU - Europa 8
JM - Giamaica 7
PE - Perù 7
GT - Guatemala 6
NI - Nicaragua 6
PH - Filippine 6
RO - Romania 6
AE - Emirati Arabi Uniti 5
DK - Danimarca 5
PK - Pakistan 5
PY - Paraguay 5
TN - Tunisia 5
TW - Taiwan 5
AZ - Azerbaigian 3
CW - ???statistics.table.value.countryCode.CW??? 3
DZ - Algeria 3
EG - Egitto 3
IL - Israele 3
JO - Giordania 3
MD - Moldavia 3
MY - Malesia 3
SV - El Salvador 3
BH - Bahrain 2
BO - Bolivia 2
DO - Repubblica Dominicana 2
GP - Guadalupe 2
KE - Kenya 2
KZ - Kazakistan 2
LB - Libano 2
MN - Mongolia 2
NG - Nigeria 2
NP - Nepal 2
PR - Porto Rico 2
PS - Palestinian Territory 2
PT - Portogallo 2
SN - Senegal 2
AG - Antigua e Barbuda 1
AU - Australia 1
BB - Barbados 1
BG - Bulgaria 1
BS - Bahamas 1
CY - Cipro 1
ET - Etiopia 1
GD - Grenada 1
GR - Grecia 1
HN - Honduras 1
HR - Croazia 1
HT - Haiti 1
IS - Islanda 1
LU - Lussemburgo 1
LY - Libia 1
MK - Macedonia 1
NZ - Nuova Zelanda 1
PA - Panama 1
Totale 12.412
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Città #
Dublin 804
Jacksonville 573
San Jose 457
Hong Kong 352
Singapore 289
Ashburn 276
Dearborn 266
Council Bluffs 249
Beijing 226
Chandler 223
Moscow 157
Wilmington 126
Ho Chi Minh City 124
Piemonte 119
Los Angeles 116
Ann Arbor 113
Lauterbourg 104
Lawrence 99
Princeton 99
Hanoi 98
Columbus 86
San Mateo 82
New York 75
Buffalo 71
Munich 65
Santa Clara 62
Bremen 60
Novara 55
Brno 50
Phoenix 46
Andover 45
Orem 44
São Paulo 41
Milan 39
Boardman 31
Houston 31
Dallas 30
Seoul 30
Toronto 30
Frankfurt am Main 29
Guangzhou 27
Denver 26
Chicago 25
The Dalles 25
Warsaw 25
Brooklyn 23
Turin 23
Cotonou 21
London 21
Montreal 20
Chennai 19
Tokyo 19
Vercelli 19
Nanjing 18
Philadelphia 18
Tianjin 18
Woodbridge 18
Brussels 17
Mexico City 17
Redondo Beach 17
Helsinki 16
Kunming 16
Atlanta 15
Boston 15
Haiphong 15
Manchester 15
Rome 15
Seattle 15
Strasbourg 15
Kocaeli 14
Nuremberg 14
St Louis 14
Da Nang 13
Poplar 13
Assago 12
Hangzhou 12
Johannesburg 12
Rio de Janeiro 12
Stockholm 12
Hefei 11
Naples 11
Norwalk 11
Ankara 10
Carmagnola 10
Guayaquil 10
North Bergen 10
Amsterdam 9
Jakarta 9
Torino 9
Bangkok 8
Barnet 8
Bexley 8
Las Vegas 8
Monmouth Junction 8
Mumbai 8
Nanchang 8
Palermo 8
San Francisco 8
Shenzhen 8
Turku 8
Totale 6.741
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Nome #
Structural investigations on Zmp1 from Mycobacterium tuberculosis, a Zn-metalloprotease that prevents inflammasome activation and phagosome maturation 229
Crystal structure of Mycobacterium tuberculosis O6-methylguanine-DNA methyltransferase protein clusters assembled onto damaged DNA 184
Curcumin-based-fluorescent probes targeting ALDH1A3 as a promising tool for glioblastoma precision surgery and early diagnosis 177
A nicotinamide phosphoribosyltransferase–GAPDH interaction sustains the stress-induced NMN/NAD+ salvage pathway in the nucleus 175
Biochemical and structural investigations on phosphoribosylpyrophosphate synthetase from Mycobacterium smegmatis 171
Crystal structure of human nicotinic acid phosphoribosyltransferase 163
Progress in the Field of Aldehyde Dehydrogenase Inhibitors: Novel Imidazo[1,2-a]pyridines against the 1A Family 161
Mechanistic understanding of UvrA damage detection and lesion hand-off to UvrB in Nucleotide Excision Repair 160
Targeting NAD-dependent dehydrogenases in drug discovery against infectious diseases and cancer 155
Interdomain interactions rearrangements control the reaction steps of a thermostable DNA alkyltransferase 153
A specific inhibitor of ALDH1A3 regulates retinoic acid biosynthesis in glioma stem cells 150
Extracellular nicotinamide phosphoribosyltransferase (NAMPT) promotes M2 macrophage polarization in chronic lymphocytic leukemia. 149
Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein 148
Absolute structure and structure-function relationships of 4R,2’R and 4S,2’S Pidotimod 148
Hit discovery of Mycobacterium tuberculosis inosine 5′-monophosphate dehydrogenase, GuaB2, inhibitors 146
A selective competitive inhibitor of aldehyde dehydrogenase 1A3 hinders cancer cell growth, invasiveness and stemness in vitro 146
Biochemical characterization of Mycobacterium tuberculosis dihydroorotate dehydrogenase and identification of a selective inhibitor 144
An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent 141
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Aryloxyaryl Moiety 138
AI is a viable alternative to high throughput screening: a 318-target study 137
A NOVEL DEAMIDO-NAD BINDING SITE REVEALED BY THE TRAPPED NAD-ADENYLATE INTERMEDIATE IN THE NAD SYNTHETASE STRUCTURE 137
Targeting Genome Integrity in Mycobacterium Tuberculosis: From Nucleotide Synthesis to DNA Replication and Repair 137
Biochemical and Structural Studies of the Mycobacterium tuberculosis O6-Methylguanine Methyltransferase and Mutated Variants 135
Structure of Thermococcus litoralis trans-3-hydroxy-L-proline dehydratase in the free and substrate-complexed form 132
Crystal structure of human aldehyde dehydrogenase 1A3 complexed with NAD+ and retinoic acid 130
Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment 130
Biochemical and structural investigations on kynurenine aminotransferase II: an example of conformation-driven species-specific inhibition? 129
Crystal structure of Haemophilus influenzae 3-isopropylmalate dehydrogenase (LeuB) in complex with the inhibitor O-isobutenyl oxalylhydroxamate 129
Biochemical and structural analysis of a cytosolic sulfotransferase of the malaria vector Anopheles gambiae overexpressed in the reproductive tissues 128
Crystal structure-based selective targeting of the pyridoxal 5'-phosphate dependent enzyme kynurenine aminotransferase II for cognitive enhancement 128
Binding of non-catalytic ATP to human hexokinase I highlights the structural components for enzyme-membrane association control RID D-5386-2011 127
European education corridors: opportunity for academic solidarity 126
A novel fold revealed by Mycobacterium tuberculosis NAD kinase, a key allosteric enzyme in NADP biosynthesis 125
Extracellular NAD+ enhances PARP-dependent DNA repair capacity independently of CD73 activity 125
Every OGT is illuminated â ¦ By fluorescent and synchrotron lights 121
Design, synthesis, SAR and biological investigation of 3-(carboxymethyl)rhodanine and aminothiazole inhibitors of Mycobacterium tuberculosis Zmp1 121
Study of Anopheles gambiae 3-hydroxykynurenine transaminase activity and inhibition by LC-MS/MS method 121
Biochemical characterization of Plasmodium falciparum CDPK4 and Anopheles gambiae TDO: two antimalarial targets 120
Crystal structure of the Mycobacterium tuberculosis phosphate binding protein PstS3 119
Functional characterization of the Mycobacterium tuberculosis zinc metallopeptidase Zmp1 and identification of potential substrates. 117
Mycobacterium tuberculosis Molecular Determinants of Infection, Survival Strategies, and Vulnerable Targets 117
Crystal structure of human kynurenine aminotransferase II, a drug target for the treatment of schizophrenia 116
Mycobacterium tuberculosis UvrB forms dimers in solution and interacts with UvrA in the absence of ligands 116
The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis 115
Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis 115
Heterologous expression, purification, and enzymatic activity of Mycobacterium tuberculosis NAD(+) synthetase 114
Allosteric regulation of Bacillus subtilis NAD kinase by quinolinic acid 114
Synthesis and Structure–Activity relationship of 1-(5-isoquinolinesulfonyl)piperazine analogues as inhibitors of Mycobacterium tuberculosis IMPDH 113
Crystal Structure of Mycobacterium tuberculosis Zinc-dependent Metalloprotease-1 (Zmp1), a Metalloprotease Involved in Pathogenicity RID D-2548-2009 112
A covalent modification of NADP(+) revealed by the atomic resolution structure of FprA, a Mycobacterium tuberculosis oxidoreductase RID D-7098-2011 111
Crystal structure of human kynurenine aminotransferase I 110
Human alpha-thrombin inhibition by the active site titrant Nalpha-(N,N-dimethylcarbamoyl)-alpha-azalysine-p-nitrophenyl-ester: a comparative kinetic and x-ray crystallographic study 109
Structure of nicotinamide mononucleotide adenylyltransferase: a key enzyme in NAD(+) biosynthesis 109
Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis 109
Cyanide binding to Lucina pectinata hemoglobin I and to sperm whale myoglobin: An x-ray crystallographic study RID D-5386-2011 108
Crystal structure of the Anopheles gambiae 3-hydroxykynurenine transaminase 107
Discovery of the first potent and selective Mycobacterium tuberculosis Zmp1 inhibitor 105
The integration of AlphaFold-predicted and crystal structures of human trans-3-hydroxy-l-proline dehydratase reveals a regulatory catalytic mechanism 104
The Potent Antiplasmodial Calmodulin-Antagonist Trifluoperazine Inhibits Plasmodium Falciparum Calcium-Dependent Protein Kinase 4. 104
Expanding benzoxazole based inosine 5'-monophosphate dehydrogenase (IMPDH) inhibitor structure-activity as potential anti-tuberculosis agents 104
The synthesis of kynurenic acid in mammals: an updated kynurenine aminotransferase structural KATalogue 104
Cryo-EM-based structural investigation of Mycobacterium tuberculosis Nucleotide Excision Repair 103
Essential but not vulnerable: indazole sulfonamides targeting inosine monophosphate dehydrogenase as potential leads against Mycobacterium tuberculosis 103
Cryo-EM-based structural investigation of Mycobacterium tuberculosis Nucleotide Excision Repair 102
Functional modulation by lactate of myoglobin. A monomeric allosteric hemoprotein 102
Curiosity to kill the KAT (kynurenine aminotransferase): structural insights into brain kynurenic acid synthesis 102
Crystal structure of Escherichia coli pyruvate kinase type-I: molecular basis of the allosteric transition 100
Structure of the sulfide-reactive hemoglobin from the clam Lucina pectinata crystallographic analysis at 1.5 Å resolution 99
Expression, purification and characterisation of haemophilus influenzae 3-isopropylmalate dehydrogenase (LeuB) 99
Biochemical mechanisms leading to tryptophan 2,3-dioxygenase activation 98
The crystal structure of human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis 98
+Mycobacterium tuberculosis Phosphoribosylpyrophosphate Synthetase: Biochemical Features of a Crucial Enzyme for Mycobacterial Cell Wall Biosynthesis 98
Human kynurenine aminotransferase II--reactivity with substrates and inhibitors 97
The structure of Rigidoporus lignosus laccase containing a full complement of copper ions, reveals an asymmetrical arrangement for the T3 copper pair 97
The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology 97
Analysis of the wild-type and mutant genes encoding the enzyme mosquito kynurenine monooxygenase of the yellow fever mosquito Aedes aegypti 97
Crystal structure of D-amino acis oxidase: a case of active site mirror-image convergent evolution with flavocytochrome b2 96
New structures of allosteric proteins reveal remarkable 95
The high-resolution crystal structure of periplasmic Haemophilus influenzae NAD nucleotidase reveals a novel enzymatic function of human CD73 related to NAD metabolism 94
Sulfide recognition in Lucina pectinata hemoglobin I: a crystallographic study 93
Structural biology of enzymes involved in NAD and molybdenum cofactor biosynthesis 93
Crystal structures of Aedes aegypti alanine glyoxylate aminotransferase 93
STRUCTURE DETERMINATION OF TWO PLASMA PROTEINS: TRANSTHYRETIN AND RETINOL BINDING PROTEIN 91
Structure of human NMN adenylyltransferase - A key nuclear enzyme for NAD homeostasis 91
Purification and biochemical characterization of a recombinant Anopheles gambiae tryptophan 2,3-dioxygenase expressed in Escherichia coli 89
Structure of Thermococcus litoralis Δ1-pyrroline-2-carboxylate reductase in complex with NADH and L-proline 89
Identification and biochemical characterization of the Anopheles gambiae 3-hydroxykynurenine transaminase 89
CRYSTAL STRUCTURE OF NH3-DEPENDENT NAD SYNTHETASE FROM BACILLUS SUBTILIS 89
Nucleotide Excision Repair in Mycobacterium tuberculosis: a Cryo-EM snapshot of the damage recognition process 88
Nonvertebrate oxygen carrier hemoproteins: structural bases for reactivity 87
Human alpha-thrombin inhibition by the highly selective compounds: N-ethoxycarbonyl-D-Phe-Pro-alpha-azalysinep-nitrophenylester,N-carbobenzoxy-Pro alpha-azalysine-p-nitrophenyl-ester and Nalpha-(N,N-dimethylcarbamoyl)-?-azalysine-p-nitrophenyl-ester: a kinetic, thermodynamic and x-ray crystallographic study 84
Old and new targets for innovative antimalarial compounds: the different strategies of the Italian Malaria Network 83
Determination of H2S solubility via the reaction with ferric hemoglobin I from the bivalve mollusc Lucina pectinata 81
GDP-4-keto-6-deoxy-D-mannose epimerase/reductase from Escherichia coli, a key enzyme in the biosynthesis of GDP-L-fucose, displays the structural characteristics of the RED protein homology superfamily 81
Abstract 2302: The extracellular form of NAMPT contributes to creating a proinflammatory environment in chronic lymphocytic leukemia 80
DnaB and DciA: mechanisms of helicase loading and translocation on ssDNA 80
The biological and structural characterization of Mycobacterium tuberculosis UvrA provides novel insights into its mechanism of action RID D-2548-2009 RID F-6175-2011 79
Target Flexibility: An Emerging Consideration in Drug Discovery and Design RID A-8008-2011 79
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase, new insights into an ancient enzyme 79
Structures of citrate synthase and malate dehydrogenase ofMycobacterium tuberculosis 79
Totale 11.602
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Categoria #
all - tutte 62.234
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 62.234
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022490 0 0 0 54 27 4 56 8 55 16 110 160
2022/20231.758 128 75 110 41 150 183 39 103 835 14 48 32
2023/2024529 44 52 53 14 98 5 83 11 3 20 41 105
2024/20251.544 54 10 94 22 36 183 113 103 316 129 156 328
2025/20264.500 250 182 324 717 441 341 541 707 300 394 226 77
2026/20271.078 157 325 294 302 0 0 0 0 0 0 0 0
Totale 12.516