IRIS
RIZZI, Menico
 Distribuzione geografica
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Continente #
EU - Europa 4.258
NA - Nord America 3.603
AS - Asia 2.593
SA - Sud America 410
AF - Africa 69
Continente sconosciuto - Info sul continente non disponibili 8
OC - Oceania 2
Totale 10.943
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Nazione #
US - Stati Uniti d'America 3.516
RU - Federazione Russa 1.016
SG - Singapore 877
IE - Irlanda 804
CN - Cina 602
DE - Germania 530
IT - Italia 513
SE - Svezia 437
VN - Vietnam 396
HK - Hong Kong 353
BR - Brasile 313
UA - Ucraina 302
FR - Francia 170
FI - Finlandia 168
IN - India 124
GB - Regno Unito 114
CA - Canada 53
CZ - Repubblica Ceca 52
KR - Corea 40
AR - Argentina 35
PL - Polonia 33
TR - Turchia 28
BD - Bangladesh 27
MX - Messico 24
ES - Italia 22
JP - Giappone 22
BJ - Benin 21
AT - Austria 20
ZA - Sudafrica 19
BE - Belgio 17
ID - Indonesia 17
NL - Olanda 17
TH - Thailandia 17
EC - Ecuador 15
IQ - Iraq 15
VE - Venezuela 13
CH - Svizzera 12
IR - Iran 11
CL - Cile 10
MA - Marocco 10
CO - Colombia 9
SA - Arabia Saudita 9
UZ - Uzbekistan 9
EU - Europa 8
PE - Perù 7
EE - Estonia 6
PH - Filippine 6
RO - Romania 6
LT - Lituania 5
PK - Pakistan 5
PY - Paraguay 5
TN - Tunisia 5
TW - Taiwan 5
AE - Emirati Arabi Uniti 4
DK - Danimarca 4
AZ - Azerbaigian 3
DZ - Algeria 3
EG - Egitto 3
IL - Israele 3
JO - Giordania 3
MY - Malesia 3
BH - Bahrain 2
BO - Bolivia 2
DO - Repubblica Dominicana 2
KE - Kenya 2
KZ - Kazakistan 2
LB - Libano 2
MN - Mongolia 2
NG - Nigeria 2
NP - Nepal 2
PS - Palestinian Territory 2
PT - Portogallo 2
SN - Senegal 2
AU - Australia 1
BB - Barbados 1
BG - Bulgaria 1
BS - Bahamas 1
CY - Cipro 1
ET - Etiopia 1
GD - Grenada 1
GR - Grecia 1
HR - Croazia 1
IS - Islanda 1
JM - Giamaica 1
LU - Lussemburgo 1
LY - Libia 1
MK - Macedonia 1
NI - Nicaragua 1
NZ - Nuova Zelanda 1
PA - Panama 1
PR - Porto Rico 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
SV - El Salvador 1
SY - Repubblica araba siriana 1
UY - Uruguay 1
Totale 10.943
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Città #
Dublin 804
Jacksonville 568
Hong Kong 346
Singapore 281
Dearborn 266
San Jose 241
Ashburn 238
Chandler 223
Beijing 222
Moscow 157
Wilmington 125
Ho Chi Minh City 123
Piemonte 119
Ann Arbor 113
Lauterbourg 104
Lawrence 99
Princeton 99
Hanoi 98
Los Angeles 96
San Mateo 82
Buffalo 66
Munich 65
Bremen 60
New York 53
Novara 53
Brno 50
Andover 45
Orem 42
Milan 39
São Paulo 39
Boardman 31
Houston 31
Seoul 30
Frankfurt am Main 29
Santa Clara 28
Guangzhou 26
The Dalles 25
Warsaw 24
Toronto 22
Cotonou 21
Dallas 21
Turin 21
London 20
Chennai 19
Vercelli 19
Brooklyn 18
Nanjing 18
Tianjin 18
Woodbridge 18
Brussels 17
Montreal 17
Phoenix 17
Redondo Beach 17
Tokyo 17
Helsinki 16
Kunming 16
Haiphong 15
Strasbourg 15
Kocaeli 14
Manchester 14
Nuremberg 14
Chicago 13
Da Nang 13
Denver 13
Mexico City 13
Poplar 13
Assago 12
Johannesburg 12
Philadelphia 12
Rio de Janeiro 12
Seattle 12
Stockholm 12
Hangzhou 11
Hefei 11
Ankara 10
Carmagnola 10
Guayaquil 10
Amsterdam 9
Jakarta 9
Norwalk 9
Torino 9
Barnet 8
Bexley 8
Monmouth Junction 8
Mumbai 8
Nanchang 8
Rome 8
Turku 8
Vienna 8
Ardabil 7
Atlanta 7
Bangkok 7
Boston 7
Buenos Aires 7
Hải Dương 7
Naples 7
Paris 7
San Francisco 7
Tashkent 7
Thái Nguyên 7
Totale 5.910
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Nome #
Structural investigations on Zmp1 from Mycobacterium tuberculosis, a Zn-metalloprotease that prevents inflammasome activation and phagosome maturation 211
Crystal structure of Mycobacterium tuberculosis O6-methylguanine-DNA methyltransferase protein clusters assembled onto damaged DNA 171
A nicotinamide phosphoribosyltransferase–GAPDH interaction sustains the stress-induced NMN/NAD+ salvage pathway in the nucleus 158
Biochemical and structural investigations on phosphoribosylpyrophosphate synthetase from Mycobacterium smegmatis 147
Curcumin-based-fluorescent probes targeting ALDH1A3 as a promising tool for glioblastoma precision surgery and early diagnosis 145
Crystal structure of human nicotinic acid phosphoribosyltransferase 145
Absolute structure and structure-function relationships of 4R,2’R and 4S,2’S Pidotimod 140
Hit discovery of Mycobacterium tuberculosis inosine 5′-monophosphate dehydrogenase, GuaB2, inhibitors 136
Interdomain interactions rearrangements control the reaction steps of a thermostable DNA alkyltransferase 134
Progress in the Field of Aldehyde Dehydrogenase Inhibitors: Novel Imidazo[1,2-a]pyridines against the 1A Family 134
Mechanistic understanding of UvrA damage detection and lesion hand-off to UvrB in Nucleotide Excision Repair 130
Extracellular nicotinamide phosphoribosyltransferase (NAMPT) promotes M2 macrophage polarization in chronic lymphocytic leukemia. 127
Biochemical and Structural Studies of the Mycobacterium tuberculosis O6-Methylguanine Methyltransferase and Mutated Variants 127
Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein 126
A NOVEL DEAMIDO-NAD BINDING SITE REVEALED BY THE TRAPPED NAD-ADENYLATE INTERMEDIATE IN THE NAD SYNTHETASE STRUCTURE 124
A specific inhibitor of ALDH1A3 regulates retinoic acid biosynthesis in glioma stem cells 123
Biochemical and structural investigations on kynurenine aminotransferase II: an example of conformation-driven species-specific inhibition? 122
Targeting Genome Integrity in Mycobacterium Tuberculosis: From Nucleotide Synthesis to DNA Replication and Repair 122
An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent 121
Crystal structure-based selective targeting of the pyridoxal 5'-phosphate dependent enzyme kynurenine aminotransferase II for cognitive enhancement 120
Structure of Thermococcus litoralis trans-3-hydroxy-L-proline dehydratase in the free and substrate-complexed form 120
Biochemical and structural analysis of a cytosolic sulfotransferase of the malaria vector Anopheles gambiae overexpressed in the reproductive tissues 113
Binding of non-catalytic ATP to human hexokinase I highlights the structural components for enzyme-membrane association control RID D-5386-2011 113
Crystal structure of human aldehyde dehydrogenase 1A3 complexed with NAD+ and retinoic acid 113
European education corridors: opportunity for academic solidarity 113
AI is a viable alternative to high throughput screening: a 318-target study 112
Biochemical characterization of Plasmodium falciparum CDPK4 and Anopheles gambiae TDO: two antimalarial targets 112
Crystal structure of Haemophilus influenzae 3-isopropylmalate dehydrogenase (LeuB) in complex with the inhibitor O-isobutenyl oxalylhydroxamate 112
A selective competitive inhibitor of aldehyde dehydrogenase 1A3 hinders cancer cell growth, invasiveness and stemness in vitro 112
Every OGT is illuminated â ¦ By fluorescent and synchrotron lights 111
Design, synthesis, SAR and biological investigation of 3-(carboxymethyl)rhodanine and aminothiazole inhibitors of Mycobacterium tuberculosis Zmp1 111
A novel fold revealed by Mycobacterium tuberculosis NAD kinase, a key allosteric enzyme in NADP biosynthesis 110
Mycobacterium tuberculosis UvrB forms dimers in solution and interacts with UvrA in the absence of ligands 110
Extracellular NAD+ enhances PARP-dependent DNA repair capacity independently of CD73 activity 109
Targeting NAD-dependent dehydrogenases in drug discovery against infectious diseases and cancer 108
Functional characterization of the Mycobacterium tuberculosis zinc metallopeptidase Zmp1 and identification of potential substrates. 107
Crystal structure of human kynurenine aminotransferase II, a drug target for the treatment of schizophrenia 107
Study of Anopheles gambiae 3-hydroxykynurenine transaminase activity and inhibition by LC-MS/MS method 107
Biochemical characterization of Mycobacterium tuberculosis dihydroorotate dehydrogenase and identification of a selective inhibitor 106
Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment 105
Heterologous expression, purification, and enzymatic activity of Mycobacterium tuberculosis NAD(+) synthetase 104
Crystal structure of the Mycobacterium tuberculosis phosphate binding protein PstS3 104
Crystal structure of human kynurenine aminotransferase I 102
Allosteric regulation of Bacillus subtilis NAD kinase by quinolinic acid 102
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Aryloxyaryl Moiety 101
Mycobacterium tuberculosis Molecular Determinants of Infection, Survival Strategies, and Vulnerable Targets 101
Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis 101
Cyanide binding to Lucina pectinata hemoglobin I and to sperm whale myoglobin: An x-ray crystallographic study RID D-5386-2011 101
Structure of nicotinamide mononucleotide adenylyltransferase: a key enzyme in NAD(+) biosynthesis 100
The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis 100
A covalent modification of NADP(+) revealed by the atomic resolution structure of FprA, a Mycobacterium tuberculosis oxidoreductase RID D-7098-2011 100
Human alpha-thrombin inhibition by the active site titrant Nalpha-(N,N-dimethylcarbamoyl)-alpha-azalysine-p-nitrophenyl-ester: a comparative kinetic and x-ray crystallographic study 99
Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis 98
Crystal structure of the Anopheles gambiae 3-hydroxykynurenine transaminase 98
Curiosity to kill the KAT (kynurenine aminotransferase): structural insights into brain kynurenic acid synthesis 96
Synthesis and Structure–Activity relationship of 1-(5-isoquinolinesulfonyl)piperazine analogues as inhibitors of Mycobacterium tuberculosis IMPDH 96
Discovery of the first potent and selective Mycobacterium tuberculosis Zmp1 inhibitor 95
Essential but not vulnerable: indazole sulfonamides targeting inosine monophosphate dehydrogenase as potential leads against Mycobacterium tuberculosis 94
New structures of allosteric proteins reveal remarkable 93
Biochemical mechanisms leading to tryptophan 2,3-dioxygenase activation 93
Expression, purification and characterisation of haemophilus influenzae 3-isopropylmalate dehydrogenase (LeuB) 93
Crystal Structure of Mycobacterium tuberculosis Zinc-dependent Metalloprotease-1 (Zmp1), a Metalloprotease Involved in Pathogenicity RID D-2548-2009 93
The Potent Antiplasmodial Calmodulin-Antagonist Trifluoperazine Inhibits Plasmodium Falciparum Calcium-Dependent Protein Kinase 4. 92
+Mycobacterium tuberculosis Phosphoribosylpyrophosphate Synthetase: Biochemical Features of a Crucial Enzyme for Mycobacterial Cell Wall Biosynthesis 92
Crystal structure of D-amino acis oxidase: a case of active site mirror-image convergent evolution with flavocytochrome b2 91
Functional modulation by lactate of myoglobin. A monomeric allosteric hemoprotein 90
Crystal structure of Escherichia coli pyruvate kinase type-I: molecular basis of the allosteric transition 90
Human kynurenine aminotransferase II--reactivity with substrates and inhibitors 90
The integration of AlphaFold-predicted and crystal structures of human trans-3-hydroxy-l-proline dehydratase reveals a regulatory catalytic mechanism 89
Structure of the sulfide-reactive hemoglobin from the clam Lucina pectinata crystallographic analysis at 1.5 Å resolution 89
Cryo-EM-based structural investigation of Mycobacterium tuberculosis Nucleotide Excision Repair 88
Cryo-EM-based structural investigation of Mycobacterium tuberculosis Nucleotide Excision Repair 88
The structure of Rigidoporus lignosus laccase containing a full complement of copper ions, reveals an asymmetrical arrangement for the T3 copper pair 88
Analysis of the wild-type and mutant genes encoding the enzyme mosquito kynurenine monooxygenase of the yellow fever mosquito Aedes aegypti 88
STRUCTURE DETERMINATION OF TWO PLASMA PROTEINS: TRANSTHYRETIN AND RETINOL BINDING PROTEIN 87
Sulfide recognition in Lucina pectinata hemoglobin I: a crystallographic study 87
The crystal structure of human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis 86
The high-resolution crystal structure of periplasmic Haemophilus influenzae NAD nucleotidase reveals a novel enzymatic function of human CD73 related to NAD metabolism 86
Identification and biochemical characterization of the Anopheles gambiae 3-hydroxykynurenine transaminase 86
The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology 86
The synthesis of kynurenic acid in mammals: an updated kynurenine aminotransferase structural KATalogue 86
Structural biology of enzymes involved in NAD and molybdenum cofactor biosynthesis 85
Expanding benzoxazole based inosine 5'-monophosphate dehydrogenase (IMPDH) inhibitor structure-activity as potential anti-tuberculosis agents 85
CRYSTAL STRUCTURE OF NH3-DEPENDENT NAD SYNTHETASE FROM BACILLUS SUBTILIS 84
Structure of human NMN adenylyltransferase - A key nuclear enzyme for NAD homeostasis 79
Structure of Thermococcus litoralis Δ1-pyrroline-2-carboxylate reductase in complex with NADH and L-proline 78
Human alpha-thrombin inhibition by the highly selective compounds: N-ethoxycarbonyl-D-Phe-Pro-alpha-azalysinep-nitrophenylester,N-carbobenzoxy-Pro alpha-azalysine-p-nitrophenyl-ester and Nalpha-(N,N-dimethylcarbamoyl)-?-azalysine-p-nitrophenyl-ester: a kinetic, thermodynamic and x-ray crystallographic study 78
Old and new targets for innovative antimalarial compounds: the different strategies of the Italian Malaria Network 77
Purification and biochemical characterization of a recombinant Anopheles gambiae tryptophan 2,3-dioxygenase expressed in Escherichia coli 77
Nonvertebrate oxygen carrier hemoproteins: structural bases for reactivity 77
GDP-4-keto-6-deoxy-D-mannose epimerase/reductase from Escherichia coli, a key enzyme in the biosynthesis of GDP-L-fucose, displays the structural characteristics of the RED protein homology superfamily 76
Crystal structures of Aedes aegypti alanine glyoxylate aminotransferase 75
Nucleotide Excision Repair in Mycobacterium tuberculosis: a Cryo-EM snapshot of the damage recognition process 75
Determination of H2S solubility via the reaction with ferric hemoglobin I from the bivalve mollusc Lucina pectinata 72
Structures of citrate synthase and malate dehydrogenase ofMycobacterium tuberculosis 72
Signalling Inhibitors Against Mycobacterium tuberculosis - Early Days of a New Therapeutic Concept in Tuberculosis 72
The biological and structural characterization of Mycobacterium tuberculosis UvrA provides novel insights into its mechanism of action RID D-2548-2009 RID F-6175-2011 70
X-ray crystallography, mass spectrometry and single crystal microspectrophotometry: A multidisciplinary characterization of catechol 1,2 dioxygenase 70
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase, new insights into an ancient enzyme 70
Abstract 2302: The extracellular form of NAMPT contributes to creating a proinflammatory environment in chronic lymphocytic leukemia 70
Totale 10.259
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Categoria #
all - tutte 52.758
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 52.758
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021181 0 0 0 0 0 0 0 0 0 42 115 24
2021/2022698 38 40 130 54 27 4 56 8 55 16 110 160
2022/20231.758 128 75 110 41 150 183 39 103 835 14 48 32
2023/2024529 44 52 53 14 98 5 83 11 3 20 41 105
2024/20251.544 54 10 94 22 36 183 113 103 316 129 156 328
2025/20264.104 250 182 324 717 441 341 541 707 300 301 0 0
Totale 11.042