Integrative Multi-Omics Pofiling of Major Depressive Disorder Patients: Unveiling Biomarkers of Disease Severity and Therapy Response

Major Depressive Disorder (MDD) is a widespread psychiatric illness that profoundly impacts social and occupational functioning. Despite its prevalence, diagnosis remains clinical, based on DSM-5 criteria, with no validated biomarkers available to guide diagnosis or predict treatment response. Therapeutic decisions often rely on a trial-and-error approach, leading to poor outcomes for many patients. Recent studies highlight the gut-immune-brain axis as a key player in MDD pathophysiology, inv...

Contextualizing the Value of Freedom

Ateismo, Naturalismo e Clandestinità: il Colloquium Heptaplomeres di Jean Bodin e la sua fortuna in Francia e Germania (XVII - XVIII secolo)

This doctoral project investigates the reception and circulation of Jean Bodin’s thought in France and Germany from the late Renaissance to the early eighteenth century, with particular attention to the fortune of the Colloquium Heptaplomeres. The dissertation is structured in three parts, each devoted to a distinct phase in the dissemination and interpretation of Bodin’s intellectual legacy. The first part reconstructs the initial two phases of Bodin’s reception. The first period, from 1577 ...

Moral Intuition: its Nature and Its Normative Roles

This thesis offers a characterisation of moral intuition and presents its normative roles. I aim at describing accurately the nature and the main features of moral intuition and its connections with other mental states, and I defend the justificatory power of moral intuition within a realist and moderately foundationalist framework. In the first chapter, I support the status of moral intuition as a sui generis mental state and argue against its reduction to doxastic attitudes. I clarify the f...