MIGGIANO, RICCARDO
MIGGIANO, RICCARDO
Dipartimento di Scienze del Farmaco
A nicotinamide phosphoribosyltransferase–GAPDH interaction sustains the stress-induced NMN/NAD+ salvage pathway in the nucleus
2020-01-01 Grolla, Ambra; Miggiano, Riccardo; Di Marino, Daniele; Bianchi, Michele; Gori, Alessandro; Orsomando, Giuseppe; Gaudino, Federica; Galli, Ubaldina; Del Grosso, Erika; Mazzola, Francesca; Angeletti, Carlo; Guarneri, Martina; Torretta, Simone; Calabrò, Marta; Boumya, Sara; Fan, Xiaorui; Colombo, Giorgia; Travelli, Cristina; Rocchio, Francesca; Aronica, Eleonora; Wohlschlegel, James A; Deaglio, Silvia; Rizzi, Menico; Genazzani, Armando; Garavaglia, Silvia
Absolute structure and structure-function relationships of 4R,2’R and 4S,2’S Pidotimod
2017-01-01 Sarno, S.; Manzo, A. M.; Ferraris, D. M.; Miggiano, R.; Rizzi, M.; Palin, L.; Boccaleri, E.; Milanesio, M.
An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent
2024-01-01 Alberti, Marta; Poli, Giulio; Broggini, Luca; Sainas, Stefano; Rizzi, Menico; Boschi, Donatella; Ferraris, Davide M; Martino, Elena; Ricagno, Stefano; Tuccinardi, Tiziano; Lolli, Marco L; Miggiano, Riccardo
Anti-inflammatory Activity of Absinthin and Derivatives in Human Bronchoepithelial Cells
2020-01-01 Talmon, M.; Bosso, L.; Quaregna, M.; Lopatriello, A.; Rossi, S.; Gavioli, D.; Marotta, P.; Caprioglio, D.; Boldorini, R.; Miggiano, R.; Fresu, L. G.; Pollastro, F.
Biochemical and structural analysis of a cytosolic sulfotransferase of the malaria vector Anopheles gambiae overexpressed in the reproductive tissues
2022-01-01 Esposito Verza, Arianna; Miggiano, Riccardo; Lombardo, Fabrizio; Fiorillo, Carmine; Arcà, Bruno; Purghé, Beatrice; Del Grosso, Erika; Galli, Ubaldina; Rizzi, Menico; Rossi, Franca
Biochemical and structural investigations on phosphoribosylpyrophosphate synthetase from Mycobacterium smegmatis
2017-01-01 Donini, Stefano; Garavaglia, Silvia; Ferraris, DAVIDE MARIA; Miggiano, Riccardo; Mori, Shigetarou; Shibayama, Keigo; Rizzi, Menico
Biochemical and Structural Studies of the Mycobacterium tuberculosis O6-Methylguanine Methyltransferase and Mutated Variants
2013-01-01 Miggiano, R.; Casazza, V.; Garavaglia, Silvia; Ciaramella, M.; Perugino, G.; Rizzi, M.; Rossi, Franca
Biochemical and structural studies of the Mycobacterium tuberculosis O6-Methylguanine Methyltransferase and mutated variants.
2014-01-01 Miggiano, Riccardo
Biochemical characterization of Mycobacterium tuberculosis dihydroorotate dehydrogenase and identification of a selective inhibitor
2023-01-01 Alberti, Marta; Sainas, Stefano; Ronchi, Erika; Lolli, Marco L; Boschi, Donatella; Rizzi, Menico; Ferraris, Davide M; Miggiano, Riccardo
Cryo-EM-based structural investigation of Mycobacterium tuberculosis Nucleotide Excision Repair
2023-01-01 Genta, Marianna; Chaves, Antonio; Bolognesi, Martino; Rossi, Franca; Rizzi, Menico; Miggiano, Riccardo
Cryo-EM-based structural investigation of Mycobacterium tuberculosis Nucleotide Excision Repair
2023-01-01 Genta, Marianna; Chaves, Antonio; Bolognesi, Martino; Rossi, Franca; Rizzi, Menico; Miggiano, Riccardo
Crystal structure of a thermophilic O6-alkylguanine-DNA alkyltransferase-derived self-labeling protein-tag in covalent complex with a fluorescent probe
2018-01-01 Rossi, Franca; Morrone, Castrese; Massarotti, Alberto; Ferraris, Davide Maria; Valenti, Anna; Perugino, Giuseppe; Miggiano, Riccardo
Crystal structure of Haemophilus influenzae 3-isopropylmalate dehydrogenase (LeuB) in complex with the inhibitor O-isobutenyl oxalylhydroxamate
2020-01-01 Miggiano, R.; Martignon, S.; Minassi, A.; Rossi, F.; Rizzi, M.
Crystal structure of Mycobacterium tuberculosis O6-methylguanine-DNA methyltransferase protein clusters assembled onto damaged DNA
2016-01-01 Miggiano, Riccardo; Perugino, Giuseppe; Ciaramella, Maria; Serpe, Mario; Rejman, Dominik; Páv, Ondřej; Pohl, Radek; Garavaglia, Silvia; Lahiri, Samarpita; Rizzi, Menico; Rossi, Franca
Engineering, Characterization, and Biological Evaluation of an Antibody Targeting the HGF Receptor
2021-01-01 Desole, C.; Gallo, S.; Vitacolonna, A.; Vigna, E.; Basilico, C.; Montarolo, F.; Zuppini, F.; Casanova, E.; Miggiano, R.; Ferraris, D. M.; Bertolotto, A.; Comoglio, P. M.; Crepaldi, T.
ER-mitochondria distance is a critical parameter for efficient mitochondrial Ca2+ uptake and oxidative metabolism
2024-01-01 Dematteis, G.; Tapella, L.; Casali, C.; Talmon, M.; Tonelli, E.; Reano, S.; Ariotti, A.; Pessolano, E.; Malecka, J.; Chrostek, G.; Kulkoviene, G.; Umbrasas, D.; Distasi, C.; Grilli, M.; Ladds, G.; Filigheddu, N.; Fresu, L. G.; Mikoshiba, K.; Matute, C.; Ramos-Gonzalez, P.; Jekabsone, A.; Cali, T.; Brini, M.; Biggiogera, M.; Cavaliere, F.; Miggiano, R.; Genazzani, A. A.; Lim, D.
Every OGT is illuminated ⦠By fluorescent and synchrotron lights
2017-01-01 Miggiano, Riccardo; Valenti, Anna; Rossi, Franca; Rizzi, Menico; Perugino, Giuseppe; Ciaramella, Maria
Fine tuning of the active site modulates specificity in the interaction of O-acetylserine sulfhydrylase isozymes with serine acetyltransferase
2013-01-01 Spyrakis, Francesca; Felici, Paolo; Bayden, Alexander S.; Salsi, Enea; Miggiano, Riccardo; Kellogg, Glen E.; Cozzini, Pietro; Cook, Paul F.; Mozzarelli, Andrea; Campanini, Barbara
First thermostable CLIP-tag by rational design applied to an archaeal O6-alkyl-guanine-DNA-alkyl-transferase
2022-01-01 Merlo, R.; Mattossovich, R.; Genta, M.; Valenti, A.; Di Mauro, G.; Minassi, A.; Miggiano, R.; Perugino, G.
Identification of a Compound Inhibiting Both the Enzymatic and Nonenzymatic Functions of Indoleamine 2,3-Dioxygenase 1
2024-01-01 Panfili, Eleonora; Rezzi, Sarah Jane; Adamo, Annalisa; Mazzoletti, Daniele; Massarotti, Alberto; Miggiano, Riccardo; Fallarini, Silvia; Ambrosino, Sara; Coletti, Alice; Molinaro, Pasquale; Milella, Michele; Paiella, Salvatore; Macchiarulo, Antonio; Ugel, Stefano; Pirali, Tracey; Pallotta, Maria Teresa
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A nicotinamide phosphoribosyltransferase–GAPDH interaction sustains the stress-induced NMN/NAD+ salvage pathway in the nucleus | 1-gen-2020 | Grolla, Ambra; Miggiano, Riccardo; Di Marino, Daniele; Bianchi, Michele; Gori, Alessandro; Orsomando, Giuseppe; Gaudino, Federica; Galli, Ubaldina; Del Grosso, Erika; Mazzola, Francesca; Angeletti, Carlo; Guarneri, Martina; Torretta, Simone; Calabrò, Marta; Boumya, Sara; Fan, Xiaorui; Colombo, Giorgia; Travelli, Cristina; Rocchio, Francesca; Aronica, Eleonora; Wohlschlegel, James A; Deaglio, Silvia; Rizzi, Menico; Genazzani, Armando; Garavaglia, Silvia | |
| Absolute structure and structure-function relationships of 4R,2’R and 4S,2’S Pidotimod | 1-gen-2017 | Sarno, S.; Manzo, A. M.; Ferraris, D. M.; Miggiano, R.; Rizzi, M.; Palin, L.; Boccaleri, E.; Milanesio, M. | |
| An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent | 1-gen-2024 | Alberti, Marta; Poli, Giulio; Broggini, Luca; Sainas, Stefano; Rizzi, Menico; Boschi, Donatella; Ferraris, Davide M; Martino, Elena; Ricagno, Stefano; Tuccinardi, Tiziano; Lolli, Marco L; Miggiano, Riccardo | |
| Anti-inflammatory Activity of Absinthin and Derivatives in Human Bronchoepithelial Cells | 1-gen-2020 | Talmon, M.; Bosso, L.; Quaregna, M.; Lopatriello, A.; Rossi, S.; Gavioli, D.; Marotta, P.; Caprioglio, D.; Boldorini, R.; Miggiano, R.; Fresu, L. G.; Pollastro, F. | |
| Biochemical and structural analysis of a cytosolic sulfotransferase of the malaria vector Anopheles gambiae overexpressed in the reproductive tissues | 1-gen-2022 | Esposito Verza, Arianna; Miggiano, Riccardo; Lombardo, Fabrizio; Fiorillo, Carmine; Arcà, Bruno; Purghé, Beatrice; Del Grosso, Erika; Galli, Ubaldina; Rizzi, Menico; Rossi, Franca | |
| Biochemical and structural investigations on phosphoribosylpyrophosphate synthetase from Mycobacterium smegmatis | 1-gen-2017 | Donini, Stefano; Garavaglia, Silvia; Ferraris, DAVIDE MARIA; Miggiano, Riccardo; Mori, Shigetarou; Shibayama, Keigo; Rizzi, Menico | |
| Biochemical and Structural Studies of the Mycobacterium tuberculosis O6-Methylguanine Methyltransferase and Mutated Variants | 1-gen-2013 | Miggiano, R.; Casazza, V.; Garavaglia, Silvia; Ciaramella, M.; Perugino, G.; Rizzi, M.; Rossi, Franca | |
| Biochemical and structural studies of the Mycobacterium tuberculosis O6-Methylguanine Methyltransferase and mutated variants. | 1-gen-2014 | Miggiano, Riccardo | |
| Biochemical characterization of Mycobacterium tuberculosis dihydroorotate dehydrogenase and identification of a selective inhibitor | 1-gen-2023 | Alberti, Marta; Sainas, Stefano; Ronchi, Erika; Lolli, Marco L; Boschi, Donatella; Rizzi, Menico; Ferraris, Davide M; Miggiano, Riccardo | |
| Cryo-EM-based structural investigation of Mycobacterium tuberculosis Nucleotide Excision Repair | 1-gen-2023 | Genta, Marianna; Chaves, Antonio; Bolognesi, Martino; Rossi, Franca; Rizzi, Menico; Miggiano, Riccardo | |
| Cryo-EM-based structural investigation of Mycobacterium tuberculosis Nucleotide Excision Repair | 1-gen-2023 | Genta, Marianna; Chaves, Antonio; Bolognesi, Martino; Rossi, Franca; Rizzi, Menico; Miggiano, Riccardo | |
| Crystal structure of a thermophilic O6-alkylguanine-DNA alkyltransferase-derived self-labeling protein-tag in covalent complex with a fluorescent probe | 1-gen-2018 | Rossi, Franca; Morrone, Castrese; Massarotti, Alberto; Ferraris, Davide Maria; Valenti, Anna; Perugino, Giuseppe; Miggiano, Riccardo | |
| Crystal structure of Haemophilus influenzae 3-isopropylmalate dehydrogenase (LeuB) in complex with the inhibitor O-isobutenyl oxalylhydroxamate | 1-gen-2020 | Miggiano, R.; Martignon, S.; Minassi, A.; Rossi, F.; Rizzi, M. | |
| Crystal structure of Mycobacterium tuberculosis O6-methylguanine-DNA methyltransferase protein clusters assembled onto damaged DNA | 1-gen-2016 | Miggiano, Riccardo; Perugino, Giuseppe; Ciaramella, Maria; Serpe, Mario; Rejman, Dominik; Páv, Ondřej; Pohl, Radek; Garavaglia, Silvia; Lahiri, Samarpita; Rizzi, Menico; Rossi, Franca | |
| Engineering, Characterization, and Biological Evaluation of an Antibody Targeting the HGF Receptor | 1-gen-2021 | Desole, C.; Gallo, S.; Vitacolonna, A.; Vigna, E.; Basilico, C.; Montarolo, F.; Zuppini, F.; Casanova, E.; Miggiano, R.; Ferraris, D. M.; Bertolotto, A.; Comoglio, P. M.; Crepaldi, T. | |
| ER-mitochondria distance is a critical parameter for efficient mitochondrial Ca2+ uptake and oxidative metabolism | 1-gen-2024 | Dematteis, G.; Tapella, L.; Casali, C.; Talmon, M.; Tonelli, E.; Reano, S.; Ariotti, A.; Pessolano, E.; Malecka, J.; Chrostek, G.; Kulkoviene, G.; Umbrasas, D.; Distasi, C.; Grilli, M.; Ladds, G.; Filigheddu, N.; Fresu, L. G.; Mikoshiba, K.; Matute, C.; Ramos-Gonzalez, P.; Jekabsone, A.; Cali, T.; Brini, M.; Biggiogera, M.; Cavaliere, F.; Miggiano, R.; Genazzani, A. A.; Lim, D. | |
| Every OGT is illuminated ⦠By fluorescent and synchrotron lights | 1-gen-2017 | Miggiano, Riccardo; Valenti, Anna; Rossi, Franca; Rizzi, Menico; Perugino, Giuseppe; Ciaramella, Maria | |
| Fine tuning of the active site modulates specificity in the interaction of O-acetylserine sulfhydrylase isozymes with serine acetyltransferase | 1-gen-2013 | Spyrakis, Francesca; Felici, Paolo; Bayden, Alexander S.; Salsi, Enea; Miggiano, Riccardo; Kellogg, Glen E.; Cozzini, Pietro; Cook, Paul F.; Mozzarelli, Andrea; Campanini, Barbara | |
| First thermostable CLIP-tag by rational design applied to an archaeal O6-alkyl-guanine-DNA-alkyl-transferase | 1-gen-2022 | Merlo, R.; Mattossovich, R.; Genta, M.; Valenti, A.; Di Mauro, G.; Minassi, A.; Miggiano, R.; Perugino, G. | |
| Identification of a Compound Inhibiting Both the Enzymatic and Nonenzymatic Functions of Indoleamine 2,3-Dioxygenase 1 | 1-gen-2024 | Panfili, Eleonora; Rezzi, Sarah Jane; Adamo, Annalisa; Mazzoletti, Daniele; Massarotti, Alberto; Miggiano, Riccardo; Fallarini, Silvia; Ambrosino, Sara; Coletti, Alice; Molinaro, Pasquale; Milella, Michele; Paiella, Salvatore; Macchiarulo, Antonio; Ugel, Stefano; Pirali, Tracey; Pallotta, Maria Teresa |