APRILE, SILVIO
APRILE, SILVIO
Dipartimento di Scienze del Farmaco
1,2,4-Oxadiazole-Bearing Pyrazoles as Metabolically Stable Modulators of Store-Operated Calcium Entry
2021-01-01 Aprile, Silvio; Riva, Beatrice; Bhela, Irene Preet; Cordero-Sanchez, Celia; Avino, Giulia; Genazzani, Armando; Serafini, Marta; Pirali, Tracey
A Concise Synthesis of Pyrazole Analogues of Combretastatin A1 as Potent Antitubulin Agents
2013-01-01 Zaninetti, Roberta; Cortese, Sv; Aprile, Silvio; Massarotti, Alberto; Canonico, Pier Luigi; Sorba, Giovanni; Grosa, Giorgio; Genazzani, Armando; Pirali, Tracey
A Selective ALDH1A3 Inhibitor Impairs Mesothelioma 3-D Multicellular Spheroid Growth and Neutrophil Recruitment
2023-01-01 Boumya, Sara; Fallarini, Silvia; Siragusa, Sonia; Petrarolo, Giovanni; Aprile, Silvio; Audrito, Valentina; La Motta, Concettina; Garavaglia, Silvia; Moro, Laura; Pinton, Giulia
A Versatile and Sustainable Multicomponent Platform for the Synthesis of Protein Degraders: Proof-of-Concept Application to BRD4-Degrading PROTACs
2022-01-01 Bhela, Irene Preet; Ranza, Alice; Balestrero, Federica Carolina; Serafini, Marta; Aprile, Silvio; Di Martino, Rita Maria Concetta; Condorelli, Fabrizio; Pirali, Tracey
An aryne-based three-component access to α-aroylamino amides
2017-01-01 Serafini, Marta; Griglio, Alessia; Viarengo, Sara; Aprile, Silvio; Pirali, Tracey
An Unexpected Deuterium-Induced Metabolic Switch in Doxophylline
2022-01-01 Aprile, Silvio; Colombo, Giorgia; Serafini, Marta; Di Paola, Rosanna; Pisati, Federica; Bhela, Irene Preet; Cuzzocrea, Salvatore; Grosa, Giorgio; Pirali, Tracey
Are 1,4- and 1,5-Disubstituted 1,2,3-Triazoles Good Pharmacophoric Groups?
2014-01-01 Massarotti, Alberto; Aprile, Silvio; Mercalli, Valentina; DEL GROSSO, Erika; Grosa, Giorgio; Sorba, Giovanni; Tron, Gian Cesare
Biological effects of combined resveratrol and vitamin D3 on ovarian tissue
2017-01-01 Uberti, Francesca; Morsanuto, Vera; Aprile, Silvio; Ghirlanda, Sabrina; Stoppa, Ian; Cochis, Andrea; Grosa, Giorgio; Rimondini, Lia; Molinari, Claudio Giuseppe
CBD and CBG permeation study through an artificial skin-biomimetic membrane
2022-01-01 Picco, Alice; Aprile, Silvio; Pollastro, Federica; Segale, Lorena; Bari, Elia; Torre, MARIA LUISA; Giovannelli, Lorella
CHEMICAL STABILITY STUDIES OF PROPARGYLAMINE CONTAINING-DRUGS
2016-01-01 Canavesi, Rossana; Aprile, Silvio; DEL GROSSO, Erika; Grosa, Giorgio
CHEMICAL STABILITY STUDIES OF PROPARGYLAMINE-CONTAINING DRUGS
2016-01-01 Canavesi, Rossana; Aprile, Silvio; DEL GROSSO, Erika; Grosa, Giorgio
CIC-39Na reverses the thrombocytopenia that characterizes tubular aggregate myopathy
2022-01-01 Cordero-Sanchez, Celia; Pessolano, Emanuela; Riva, Beatrice; Vismara, Mauro; Trivigno, Silvia Maria Grazia; Clemente, Nausicaa; Aprile, Silvio; Ruffinatti, Federico Alessandro; Portararo, Paola; Filigheddu, Nicoletta; Zaggia, Ivan; Bhela, Irene P; Serafini, Marta; Pirali, Tracey; Colombo, Mario P; Torti, Mauro; Sangaletti, Sabina; Bertoni, Alessandra; Genazzani, Armando
Data on metabolic stability, aqueous solubility and CYP inhibition of novel triazole-based nicotinamide phosphoribosyltransferase (NAMPT) inhibitors
2020-01-01 Aprile, Silvio; Galli, Ubaldina; Tron, Gian Cesare; Del Grosso, Erika; Travelli, Cristina; Grosa, Giorgio
Design, synthesis, and biological evaluation of combretabenzodiazepines: a novel class of anti-tubulin agents
2015-01-01 Galli, Ubaldina; Travelli, Cristina; Aprile, Silvio; Arrigoni, Elena; Torretta, Simone; Grosa, Giorgio; Massarotti, Alberto; Sorba, Giovanni; Canonico, Pier Luigi; Genazzani, Armando; Tron, Gian Cesare
Development and validation of a stability-indicating HPLC-UV method for the determination of alizapride and its degradation products
2010-01-01 Tamaro, I; Aprile, Silvio; Giovenzana, Giovanni Battista; Grosa, Giorgio
Development and validation of a stability-indicating HPLC-UV method for the determination of Thiocolchicoside and its degradation products
2017-01-01 Aprile, Silvio; Canavesi, Rossana; Bianchi, Michele; Grosa, Giorgio; DEL GROSSO, Erika
Development and validation of a stability-indicating LC–UV method for the determination of pantethine and its degradation product based on a forced degradation study
2014-01-01 Canavesi, Rossana; Aprile, Silvio; Elena, Varese; Grosa, Giorgio
DEVELOPMENT AND VALIDATION OF HPLC-UV STABILITY INDICATING METHOD FOR THE DETERMINATION OF THIOCOLCHICOSIDE AND ITS DEGRADATION PRODUCTS IN PHARMACEUTICAL DOSAGE FORM
2011-01-01 DEL GROSSO, Erika; Aprile, Silvio; Grosa, Giorgio
Discovery of Highly Potent Benzimidazole Derivatives as Indoleamine 2,3-Dioxygenase-1 (IDO1) Inhibitors: From Structure-Based Virtual Screening to in Vivo Pharmacodynamic Activity
2020-01-01 Serafini, M.; Torre, E.; Aprile, S.; Del Grosso, E.; Gesu, A.; Griglio, A.; Colombo, G.; Travelli, C.; Paiella, S.; Adamo, A.; Orecchini, E.; Coletti, A.; Pallotta, M. T.; Ugel, S.; Massarotti, A.; Pirali, T.; Fallarini, S.
Expanding the Chemical Space of Drug-like Passerini Compounds: Can α-Acyloxy Carboxamides Be Considered Hard Drugs?
2022-01-01 Brunelli, F.; Ceresa, C.; Fracchia, L.; Tron, G. C.; Aprile, S.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 1,2,4-Oxadiazole-Bearing Pyrazoles as Metabolically Stable Modulators of Store-Operated Calcium Entry | 1-gen-2021 | Aprile, Silvio; Riva, Beatrice; Bhela, Irene Preet; Cordero-Sanchez, Celia; Avino, Giulia; Genazzani, Armando; Serafini, Marta; Pirali, Tracey | |
| A Concise Synthesis of Pyrazole Analogues of Combretastatin A1 as Potent Antitubulin Agents | 1-gen-2013 | Zaninetti, Roberta; Cortese, Sv; Aprile, Silvio; Massarotti, Alberto; Canonico, Pier Luigi; Sorba, Giovanni; Grosa, Giorgio; Genazzani, Armando; Pirali, Tracey | |
| A Selective ALDH1A3 Inhibitor Impairs Mesothelioma 3-D Multicellular Spheroid Growth and Neutrophil Recruitment | 1-gen-2023 | Boumya, Sara; Fallarini, Silvia; Siragusa, Sonia; Petrarolo, Giovanni; Aprile, Silvio; Audrito, Valentina; La Motta, Concettina; Garavaglia, Silvia; Moro, Laura; Pinton, Giulia | |
| A Versatile and Sustainable Multicomponent Platform for the Synthesis of Protein Degraders: Proof-of-Concept Application to BRD4-Degrading PROTACs | 1-gen-2022 | Bhela, Irene Preet; Ranza, Alice; Balestrero, Federica Carolina; Serafini, Marta; Aprile, Silvio; Di Martino, Rita Maria Concetta; Condorelli, Fabrizio; Pirali, Tracey | |
| An aryne-based three-component access to α-aroylamino amides | 1-gen-2017 | Serafini, Marta; Griglio, Alessia; Viarengo, Sara; Aprile, Silvio; Pirali, Tracey | |
| An Unexpected Deuterium-Induced Metabolic Switch in Doxophylline | 1-gen-2022 | Aprile, Silvio; Colombo, Giorgia; Serafini, Marta; Di Paola, Rosanna; Pisati, Federica; Bhela, Irene Preet; Cuzzocrea, Salvatore; Grosa, Giorgio; Pirali, Tracey | |
| Are 1,4- and 1,5-Disubstituted 1,2,3-Triazoles Good Pharmacophoric Groups? | 1-gen-2014 | Massarotti, Alberto; Aprile, Silvio; Mercalli, Valentina; DEL GROSSO, Erika; Grosa, Giorgio; Sorba, Giovanni; Tron, Gian Cesare | |
| Biological effects of combined resveratrol and vitamin D3 on ovarian tissue | 1-gen-2017 | Uberti, Francesca; Morsanuto, Vera; Aprile, Silvio; Ghirlanda, Sabrina; Stoppa, Ian; Cochis, Andrea; Grosa, Giorgio; Rimondini, Lia; Molinari, Claudio Giuseppe | |
| CBD and CBG permeation study through an artificial skin-biomimetic membrane | 1-gen-2022 | Picco, Alice; Aprile, Silvio; Pollastro, Federica; Segale, Lorena; Bari, Elia; Torre, MARIA LUISA; Giovannelli, Lorella | |
| CHEMICAL STABILITY STUDIES OF PROPARGYLAMINE CONTAINING-DRUGS | 1-gen-2016 | Canavesi, Rossana; Aprile, Silvio; DEL GROSSO, Erika; Grosa, Giorgio | |
| CHEMICAL STABILITY STUDIES OF PROPARGYLAMINE-CONTAINING DRUGS | 1-gen-2016 | Canavesi, Rossana; Aprile, Silvio; DEL GROSSO, Erika; Grosa, Giorgio | |
| CIC-39Na reverses the thrombocytopenia that characterizes tubular aggregate myopathy | 1-gen-2022 | Cordero-Sanchez, Celia; Pessolano, Emanuela; Riva, Beatrice; Vismara, Mauro; Trivigno, Silvia Maria Grazia; Clemente, Nausicaa; Aprile, Silvio; Ruffinatti, Federico Alessandro; Portararo, Paola; Filigheddu, Nicoletta; Zaggia, Ivan; Bhela, Irene P; Serafini, Marta; Pirali, Tracey; Colombo, Mario P; Torti, Mauro; Sangaletti, Sabina; Bertoni, Alessandra; Genazzani, Armando | |
| Data on metabolic stability, aqueous solubility and CYP inhibition of novel triazole-based nicotinamide phosphoribosyltransferase (NAMPT) inhibitors | 1-gen-2020 | Aprile, Silvio; Galli, Ubaldina; Tron, Gian Cesare; Del Grosso, Erika; Travelli, Cristina; Grosa, Giorgio | |
| Design, synthesis, and biological evaluation of combretabenzodiazepines: a novel class of anti-tubulin agents | 1-gen-2015 | Galli, Ubaldina; Travelli, Cristina; Aprile, Silvio; Arrigoni, Elena; Torretta, Simone; Grosa, Giorgio; Massarotti, Alberto; Sorba, Giovanni; Canonico, Pier Luigi; Genazzani, Armando; Tron, Gian Cesare | |
| Development and validation of a stability-indicating HPLC-UV method for the determination of alizapride and its degradation products | 1-gen-2010 | Tamaro, I; Aprile, Silvio; Giovenzana, Giovanni Battista; Grosa, Giorgio | |
| Development and validation of a stability-indicating HPLC-UV method for the determination of Thiocolchicoside and its degradation products | 1-gen-2017 | Aprile, Silvio; Canavesi, Rossana; Bianchi, Michele; Grosa, Giorgio; DEL GROSSO, Erika | |
| Development and validation of a stability-indicating LC–UV method for the determination of pantethine and its degradation product based on a forced degradation study | 1-gen-2014 | Canavesi, Rossana; Aprile, Silvio; Elena, Varese; Grosa, Giorgio | |
| DEVELOPMENT AND VALIDATION OF HPLC-UV STABILITY INDICATING METHOD FOR THE DETERMINATION OF THIOCOLCHICOSIDE AND ITS DEGRADATION PRODUCTS IN PHARMACEUTICAL DOSAGE FORM | 1-gen-2011 | DEL GROSSO, Erika; Aprile, Silvio; Grosa, Giorgio | |
| Discovery of Highly Potent Benzimidazole Derivatives as Indoleamine 2,3-Dioxygenase-1 (IDO1) Inhibitors: From Structure-Based Virtual Screening to in Vivo Pharmacodynamic Activity | 1-gen-2020 | Serafini, M.; Torre, E.; Aprile, S.; Del Grosso, E.; Gesu, A.; Griglio, A.; Colombo, G.; Travelli, C.; Paiella, S.; Adamo, A.; Orecchini, E.; Coletti, A.; Pallotta, M. T.; Ugel, S.; Massarotti, A.; Pirali, T.; Fallarini, S. | |
| Expanding the Chemical Space of Drug-like Passerini Compounds: Can α-Acyloxy Carboxamides Be Considered Hard Drugs? | 1-gen-2022 | Brunelli, F.; Ceresa, C.; Fracchia, L.; Tron, G. C.; Aprile, S. |