Sfoglia per Autore
Progress in the Field of Aldehyde Dehydrogenase Inhibitors: Novel Imidazo[1,2-a]pyridines against the 1A Family
2020-01-01 Quattrini, Luca; Gelardi, Edoardo Luigi Maria; Petrarolo, Giovanni; Colombo, Giorgia; Ferraris, Davide Maria; Picarazzi, Francesca; Rizzi, Menico; Garavaglia, Silvia; La Motta, Concettina
Study of Anopheles gambiae 3-hydroxykynurenine transaminase activity and inhibition by LC-MS/MS method
2019-01-01 Canavesi, Rossana; Miggiano, Riccardo; Stella, Martina; Galli, Ubaldina; Rossi, Franca; Rizzi, Menico; Del Grosso, Erika
Structure of Thermococcus litoralis trans-3-hydroxy-L-proline dehydratase in the free and substrate-complexed form
2019-01-01 Ferraris, D. M.; Miggiano, R.; Watanabe, S.; Rizzi, M.
The synthesis of kynurenic acid in mammals: an updated kynurenine aminotransferase structural KATalogue
2019-01-01 Rossi, Franca; Miggiano, Riccardo; Ferraris, Davide M.; Rizzi, Menico
The INN global nomenclature of biological medicines: A continuous challenge
2019-01-01 Robertson, James S; Chui, Wai-Keung; Genazzani, Armando; Malan, Sarel F; López de la Rica Manjavacas, Ana; Mignot, Gilles; Thorpe, Robin; Balocco, Raffaella; Rizzi, Menico
Synthesis and Structure–Activity relationship of 1-(5-isoquinolinesulfonyl)piperazine analogues as inhibitors of Mycobacterium tuberculosis IMPDH
2019-01-01 Singh, Vinayak; Pacitto, Angela; Donini, Stefano; Ferraris, Davide M.; Boros, Sándor; Illyés, Eszter; Szokol, Bálint; Rizzi, Menico; Blundell, Tom L.; Ascher, David B.; Pato, Janos; Mizrahi, Valerie
Expanding benzoxazole based inosine 5'-monophosphate dehydrogenase (IMPDH) inhibitor structure-activity as potential anti-tuberculosis agents
2018-01-01 Chacko, Shibin; Boshoff, Helena I. M.; Singh, Vinayak; Ferraris, Davide M.; Gollapalli, Deviprasad R.; Zhang, Minjia; Lawson, Ann P.; Pepi, Michael J.; Joachimiak, Andrzej; Rizzi, Menico; Mizrahi, Valerie; Cuny, Gregory D.; Hedstrom, Lizbeth
Mycobacterium tuberculosis Molecular Determinants of Infection, Survival Strategies, and Vulnerable Targets
2018-01-01 Ferraris, Davide M; Miggiano, Riccardo; Rossi, Franca; Rizzi, Menico
Mycobacterium tuberculosis UvrB forms dimers in solution and interacts with UvrA in the absence of ligands
2018-01-01 Lahiri, Samarpita; Rizzi, Menico; Rossi, Franca; Miggiano, Riccardo
Hit discovery of Mycobacterium tuberculosis inosine 5′-monophosphate dehydrogenase, GuaB2, inhibitors
2018-01-01 Sahu, Niteshkumar U.; Singh, Vinayak; Ferraris, Davide M.; Rizzi, Menico; Kharkar, Prashant S.
Design, synthesis, SAR and biological investigation of 3-(carboxymethyl)rhodanine and aminothiazole inhibitors of Mycobacterium tuberculosis Zmp1
2018-01-01 Mori, Mattia; Deodato, Davide; Kasula, Mohan; Ferraris, Davide M.; Sanna, Adriana; De Logu, Alessandro; Rizzi, Menico; Botta, Maurizio
Biochemical and structural investigations on phosphoribosylpyrophosphate synthetase from Mycobacterium smegmatis
2017-01-01 Donini, Stefano; Garavaglia, Silvia; Ferraris, DAVIDE MARIA; Miggiano, Riccardo; Mori, Shigetarou; Shibayama, Keigo; Rizzi, Menico
Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis
2017-01-01 Donini, Stefano; Ferraris, DAVIDE MARIA; Miggiano, Riccardo; Massarotti, Alberto; Rizzi, Menico
Absolute structure and structure-function relationships of 4R,2’R and 4S,2’S Pidotimod
2017-01-01 Sarno, S.; Manzo, A. M.; Ferraris, D. M.; Miggiano, R.; Rizzi, M.; Palin, L.; Boccaleri, E.; Milanesio, M.
Every OGT is illuminated ⦠By fluorescent and synchrotron lights
2017-01-01 Miggiano, Riccardo; Valenti, Anna; Rossi, Franca; Rizzi, Menico; Perugino, Giuseppe; Ciaramella, Maria
Interdomain interactions rearrangements control the reaction steps of a thermostable DNA alkyltransferase
2017-01-01 Morrone, Castrese; Miggiano, Riccardo; Serpe, Mario; Massarotti, Alberto; Valenti, Anna; Del Monaco, Giovanni; Rossi, Mosè; Rossi, Franca; Rizzi, Menico; Perugino, Giuseppe; Ciaramella, Maria
Crystal structure of Mycobacterium tuberculosis O6-methylguanine-DNA methyltransferase protein clusters assembled onto damaged DNA
2016-01-01 Miggiano, Riccardo; Perugino, Giuseppe; Ciaramella, Maria; Serpe, Mario; Rejman, Dominik; Páv, Ondřej; Pohl, Radek; Garavaglia, Silvia; Lahiri, Samarpita; Rizzi, Menico; Rossi, Franca
Essential but not vulnerable: indazole sulfonamides targeting inosine monophosphate dehydrogenase as potential leads against Mycobacterium tuberculosis
2016-01-01 Park, Yumi; Pacitto, Angela; Bayliss, Tracy; Cleghorn, Laura A. T; Wang, Zhe; Hartman, Travis; Arora, Kriti; Ioerger, Thomas R; Sacchettini, Jim; Rizzi, Menico; Donini, Stefano; Blundell, Tom L; Ascher, David B; Rhee, Kyu Y; Breda, Ardala; Zhou, Nian; Dartois, Veronique; Jonnala, Surendranadha Reddy; Via, Laura E; Mizrahi, Valerie; Epemolu, Ola; Stojanovski, Laste; Simeons, Frederick Ryan Carne; Osuna Cabello, Maria; Ellis, Lucy; Mackenzie, Claire J; Smith, Alasdair R. C; Davis, Susan Helen; Murugesan, Dinakaran; Buchanan, Kirsteen I; Turner, Penelope A; Huggett, Margaret; Zuccotto, Fabio; Rebollo Lopez, Maria Jose; Lafuente Monasterio, Maria Jose; Sanz, Olalla; Santos Diaz, Gracia; Lelièvre, Joël; Ballell, Lluis; Selenski, Carolyn; Axtman, Matthew; Ghidelli Disse, Sonja; Pflaumer, Hannah; Boesche, Markus; Drewes, Gerard; Freiberg, Gail; Kurnick, Matthew D; Srikumaran, Myron; Kempf, Dale J; Green, Simon R; Ray, Peter Christopher; Read, Kevin D; Wyatt, Paul G; Barry Rd, Clifton E; Boshoff, Helena I. M.
Crystal structure of human aldehyde dehydrogenase 1A3 complexed with NAD+ and retinoic acid
2016-01-01 Moretti, Andrea; Li, Jianfeng; Donini, Stefano; Sobol, Robert W.; Rizzi, Menico; Garavaglia, Silvia
The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis
2016-01-01 Singh, Vinayak; Donini, Stefano; Pacitto, Angela; Sala, Claudia; Hartkoorn, Ruben C; Dhar, Neeraj; Keri, Gyorgy; Ascher, David B; Mondésert, Guillaume; Vocat, Anthony; Lupien, Andréanne; Sommer, Raphael; Vermet, Hélène; Lagrange, Sophie; Buechler, Joe; Warner, Digby F; Mckinney, John D; Pato, Janos; Cole, Stewart T; Blundell, Tom L; Rizzi, Menico; Mizrahi, Valerie
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Progress in the Field of Aldehyde Dehydrogenase Inhibitors: Novel Imidazo[1,2-a]pyridines against the 1A Family | 1-gen-2020 | Quattrini, Luca; Gelardi, Edoardo Luigi Maria; Petrarolo, Giovanni; Colombo, Giorgia; Ferraris, Davide Maria; Picarazzi, Francesca; Rizzi, Menico; Garavaglia, Silvia; La Motta, Concettina | |
| Study of Anopheles gambiae 3-hydroxykynurenine transaminase activity and inhibition by LC-MS/MS method | 1-gen-2019 | Canavesi, Rossana; Miggiano, Riccardo; Stella, Martina; Galli, Ubaldina; Rossi, Franca; Rizzi, Menico; Del Grosso, Erika | |
| Structure of Thermococcus litoralis trans-3-hydroxy-L-proline dehydratase in the free and substrate-complexed form | 1-gen-2019 | Ferraris, D. M.; Miggiano, R.; Watanabe, S.; Rizzi, M. | |
| The synthesis of kynurenic acid in mammals: an updated kynurenine aminotransferase structural KATalogue | 1-gen-2019 | Rossi, Franca; Miggiano, Riccardo; Ferraris, Davide M.; Rizzi, Menico | |
| The INN global nomenclature of biological medicines: A continuous challenge | 1-gen-2019 | Robertson, James S; Chui, Wai-Keung; Genazzani, Armando; Malan, Sarel F; López de la Rica Manjavacas, Ana; Mignot, Gilles; Thorpe, Robin; Balocco, Raffaella; Rizzi, Menico | |
| Synthesis and Structure–Activity relationship of 1-(5-isoquinolinesulfonyl)piperazine analogues as inhibitors of Mycobacterium tuberculosis IMPDH | 1-gen-2019 | Singh, Vinayak; Pacitto, Angela; Donini, Stefano; Ferraris, Davide M.; Boros, Sándor; Illyés, Eszter; Szokol, Bálint; Rizzi, Menico; Blundell, Tom L.; Ascher, David B.; Pato, Janos; Mizrahi, Valerie | |
| Expanding benzoxazole based inosine 5'-monophosphate dehydrogenase (IMPDH) inhibitor structure-activity as potential anti-tuberculosis agents | 1-gen-2018 | Chacko, Shibin; Boshoff, Helena I. M.; Singh, Vinayak; Ferraris, Davide M.; Gollapalli, Deviprasad R.; Zhang, Minjia; Lawson, Ann P.; Pepi, Michael J.; Joachimiak, Andrzej; Rizzi, Menico; Mizrahi, Valerie; Cuny, Gregory D.; Hedstrom, Lizbeth | |
| Mycobacterium tuberculosis Molecular Determinants of Infection, Survival Strategies, and Vulnerable Targets | 1-gen-2018 | Ferraris, Davide M; Miggiano, Riccardo; Rossi, Franca; Rizzi, Menico | |
| Mycobacterium tuberculosis UvrB forms dimers in solution and interacts with UvrA in the absence of ligands | 1-gen-2018 | Lahiri, Samarpita; Rizzi, Menico; Rossi, Franca; Miggiano, Riccardo | |
| Hit discovery of Mycobacterium tuberculosis inosine 5′-monophosphate dehydrogenase, GuaB2, inhibitors | 1-gen-2018 | Sahu, Niteshkumar U.; Singh, Vinayak; Ferraris, Davide M.; Rizzi, Menico; Kharkar, Prashant S. | |
| Design, synthesis, SAR and biological investigation of 3-(carboxymethyl)rhodanine and aminothiazole inhibitors of Mycobacterium tuberculosis Zmp1 | 1-gen-2018 | Mori, Mattia; Deodato, Davide; Kasula, Mohan; Ferraris, Davide M.; Sanna, Adriana; De Logu, Alessandro; Rizzi, Menico; Botta, Maurizio | |
| Biochemical and structural investigations on phosphoribosylpyrophosphate synthetase from Mycobacterium smegmatis | 1-gen-2017 | Donini, Stefano; Garavaglia, Silvia; Ferraris, DAVIDE MARIA; Miggiano, Riccardo; Mori, Shigetarou; Shibayama, Keigo; Rizzi, Menico | |
| Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis | 1-gen-2017 | Donini, Stefano; Ferraris, DAVIDE MARIA; Miggiano, Riccardo; Massarotti, Alberto; Rizzi, Menico | |
| Absolute structure and structure-function relationships of 4R,2’R and 4S,2’S Pidotimod | 1-gen-2017 | Sarno, S.; Manzo, A. M.; Ferraris, D. M.; Miggiano, R.; Rizzi, M.; Palin, L.; Boccaleri, E.; Milanesio, M. | |
| Every OGT is illuminated ⦠By fluorescent and synchrotron lights | 1-gen-2017 | Miggiano, Riccardo; Valenti, Anna; Rossi, Franca; Rizzi, Menico; Perugino, Giuseppe; Ciaramella, Maria | |
| Interdomain interactions rearrangements control the reaction steps of a thermostable DNA alkyltransferase | 1-gen-2017 | Morrone, Castrese; Miggiano, Riccardo; Serpe, Mario; Massarotti, Alberto; Valenti, Anna; Del Monaco, Giovanni; Rossi, Mosè; Rossi, Franca; Rizzi, Menico; Perugino, Giuseppe; Ciaramella, Maria | |
| Crystal structure of Mycobacterium tuberculosis O6-methylguanine-DNA methyltransferase protein clusters assembled onto damaged DNA | 1-gen-2016 | Miggiano, Riccardo; Perugino, Giuseppe; Ciaramella, Maria; Serpe, Mario; Rejman, Dominik; Páv, Ondřej; Pohl, Radek; Garavaglia, Silvia; Lahiri, Samarpita; Rizzi, Menico; Rossi, Franca | |
| Essential but not vulnerable: indazole sulfonamides targeting inosine monophosphate dehydrogenase as potential leads against Mycobacterium tuberculosis | 1-gen-2016 | Park, Yumi; Pacitto, Angela; Bayliss, Tracy; Cleghorn, Laura A. T; Wang, Zhe; Hartman, Travis; Arora, Kriti; Ioerger, Thomas R; Sacchettini, Jim; Rizzi, Menico; Donini, Stefano; Blundell, Tom L; Ascher, David B; Rhee, Kyu Y; Breda, Ardala; Zhou, Nian; Dartois, Veronique; Jonnala, Surendranadha Reddy; Via, Laura E; Mizrahi, Valerie; Epemolu, Ola; Stojanovski, Laste; Simeons, Frederick Ryan Carne; Osuna Cabello, Maria; Ellis, Lucy; Mackenzie, Claire J; Smith, Alasdair R. C; Davis, Susan Helen; Murugesan, Dinakaran; Buchanan, Kirsteen I; Turner, Penelope A; Huggett, Margaret; Zuccotto, Fabio; Rebollo Lopez, Maria Jose; Lafuente Monasterio, Maria Jose; Sanz, Olalla; Santos Diaz, Gracia; Lelièvre, Joël; Ballell, Lluis; Selenski, Carolyn; Axtman, Matthew; Ghidelli Disse, Sonja; Pflaumer, Hannah; Boesche, Markus; Drewes, Gerard; Freiberg, Gail; Kurnick, Matthew D; Srikumaran, Myron; Kempf, Dale J; Green, Simon R; Ray, Peter Christopher; Read, Kevin D; Wyatt, Paul G; Barry Rd, Clifton E; Boshoff, Helena I. M. | |
| Crystal structure of human aldehyde dehydrogenase 1A3 complexed with NAD+ and retinoic acid | 1-gen-2016 | Moretti, Andrea; Li, Jianfeng; Donini, Stefano; Sobol, Robert W.; Rizzi, Menico; Garavaglia, Silvia | |
| The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis | 1-gen-2016 | Singh, Vinayak; Donini, Stefano; Pacitto, Angela; Sala, Claudia; Hartkoorn, Ruben C; Dhar, Neeraj; Keri, Gyorgy; Ascher, David B; Mondésert, Guillaume; Vocat, Anthony; Lupien, Andréanne; Sommer, Raphael; Vermet, Hélène; Lagrange, Sophie; Buechler, Joe; Warner, Digby F; Mckinney, John D; Pato, Janos; Cole, Stewart T; Blundell, Tom L; Rizzi, Menico; Mizrahi, Valerie |
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