Sfoglia per Autore
Photocatalytic Isocyanide-based Multicomponent Domino Cascade Towards the Stereoselective Formation of Iminofurans
2020-01-01 Pelliccia, Sveva; Alfano, Antonella Ilenia; Luciano, Paolo; Novellino, Ettore; Massarotti, Alberto; Tron, Gian Cesare; Ravelli, Davide; Giustiniano, Mariateresa
Recent Advances in NAMPT Inhibitors: A Novel Immunotherapic Strategy
2020-01-01 Galli, Ubaldina; Colombo, Giorgia; Travelli, Cristina; Tron, Gian Cesare; Genazzani, Armando; Grolla, Ambra
Structure activity relationship studies on Amb639752: toward the identification of a common pharmacophoric structure for DGKα inhibitors
2020-01-01 Velnati, Suresh; Massarotti, Alberto; Antona, Annamaria; Talmon, Maria; Fresu, Luigia Grazia; Galetto, Alessandra Silvia; Capello, Daniela; Bertoni, Alessandra; Mercalli, Valentina; Graziani, Andrea; Tron, Gian Cesare; Baldanzi, Gianluca
Click 1,2,3-triazoles in drug discovery and development: From the flask to the clinic?
2020-01-01 Serafini, M.; Pirali, T.; Tron, G. C.
Visible-Light Photocatalytic Functionalization of Isocyanides for the Synthesis of Secondary Amides and Ketene Aminals
2020-01-01 Cannalire, R.; Amato, J.; Summa, V.; Novellino, E.; Tron, G. C.; Giustiniano, M.
Bio-Inspired Dual-Selective BCL-2/c-MYC G-Quadruplex Binders: Design, Synthesis, and Anticancer Activity of Drug-like Imidazo[2,1-i]purine Derivatives
2020-01-01 Pelliccia, Sveva; Amato, Jussara; Capasso, Domenica; Di Gaetano, Sonia; Massarotti, Alberto; Piccolo, Marialuisa; Irace, Carlo; Tron, Gian Cesare; Pagano, Bruno; Randazzo, Antonio; Novellino, Ettore; Giustiniano, Mariateresa
Metabolic Fate of the Isocyanide Moiety: Are Isocyanides Pharmacophore Groups Neglected by Medicinal Chemists?
2020-01-01 Galli, Ubaldina; Tron, Gian Cesare; Purghè, Beatrice; Grosa, Giorgio; Aprile, Silvio
Nicotinamide Phosphoribosyltransferase (NAMPT) acts as a metabolic gate for mobilization of myeloid-derived suppressor cells
2019-01-01 Travelli, Cristina; Consonni, Francesca Maria; Sangaletti, Sabina; Storto, Mariangela; Morlacchi, Sara; Grolla, Ambra; Galli, Ubaldina; Tron, Gian Cesare; Portararo, Paola; Rimassa, Lorenza; Pressiani, Tiziana; Mazzone, Massimiliano; Trovato, Rosalinda; Ugel, Stefano; Bronte, Vincenzo; Tripodo, Claudio; Colombo, Mario P; Genazzani, Armando; Sica, Antonio
α-Amino Acids as Synthons in the Ugi-5-Centers-4-Components Reaction: Chemistry and Applications
2019-01-01 Pellicia, Sveva; Alfano Ilenia, Antonella; Galli, Ubaldina; Novellino, Ettore; Giustiniano, Mariateresa; Tron, Gian Cesare
Drug Discovery for Soft Drugs on TRPV1 and TRPM8 Channels Using the Passerini Reaction
2019-01-01 Pirali, Tracey; Galli, Ubaldina; Serafini, Marta; Griglio, Alessia; Genazzani, Armando; Tron, Gian Cesare
Exploiting the Nucleophilicity of the Nitrogen Atom of Imidazoles: One-Pot Three-Component Synthesis of Imidazo-Pyrazines
2019-01-01 Galli, Ubaldina; Hysenlika, Rejdia; Meneghetti, Fiorella; Del Grosso, Erika; Pelliccia, Sveva; Novellino, Ettore; Giustiniano, Mariateresa; Tron, Gian Cesare
Aryl Azides as Forgotten Electrophiles in the Van Leusen Reaction: A Multicomponent Transformation Affording 4-Tosyl-1-arylimidazoles
2019-01-01 Necardo, Cristiana; Alfano, Antonella Ilenia; Del Grosso, Erika; Pelliccia, Sveva; Galli, Ubaldina; Novellino, Ettore; Meneghetti, Fiorella; Giustiniano, Mariateresa; Tron, Gian Cesare
Identification of potent triazolylpyridine nicotinamide phosphoribosyltransferase (NAMPT) inhibitors bearing a 1,2,3-triazole tail group
2019-01-01 Travelli, Cristina; Aprile, Silvio; Mattoteia, Daiana; Colombo, Giorgia; Clemente, Nausicaa; Scanziani, Eugenio; Terrazzino, Salvatore; Alisi, Maria Alessandra; Polenzani, Lorenzo; Grosa, Giorgio; Genazzani, Armando; Tron, Gian Cesare; Galli, Ubaldina
Identification of a novel DGKa inhibitor for XLP-1 therapy by virtual screening
2019-01-01 Velnati, Suresh; Ruffo, Elisa; Massarotti, Alberto; Talmon, Maria; Sai Sandeep Varma, Konduru; Gesu, Alessandro; Fresu, Luigia Grazia; Snow, Andrew L.; Bertoni, Alessandra; Capello, Daniela; Tron, Gian Cesare; Graziani, Andrea; Baldanzi, Gianluca
On-water pyrrolidine-mediated domino synthesis of 2-iminoisatins
2018-01-01 Pelliccia, Sveva; Abbate, Vincenzo; Meneghetti, Fiorella; Frascione, Nunzianda; Hider, Robert Charles; Novellino, Ettore; Tron, Gian Cesare; Giustiniano, Mariateresa
Interrupted Ugi and Passerini Reactions: An Underexplored Treasure Island
2018-01-01 Giustiniano, Mariateresa; Moni, Lisa; Sangaletti, Luca; Pelliccia, Sveva; Basso, Andrea; Novellino, Ettore; Tron, Gian Cesare
Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis
2018-01-01 Campa, Carlo C; Silva, Rangel L; Margaria, Jean P; Pirali, Tracey; Mattos, Matheus S; Kraemer, Lucas R; Reis, Diego C; Grosa, Giorgio; Copperi, Francesca; Dalmarco, Eduardo M; Lima-Júnior, Roberto C P; Aprile, Silvio; Sala, Valentina; Dal Bello, Federica; Prado, Douglas Silva; Alves-Filho, Jose Carlos; Medana, Claudio; Cassali, Geovanni D; Tron, Gian Cesare; Teixeira, Mauro M; Ciraolo, Elisa; Russo, Remo C; Hirsch, Emilio
Non-hydrolytic chemoselective cleavage of Ugi tertiary amides: a mild access to N- substituted α-amino acid amides
2018-01-01 Giustiniano, Mariateresa; Pelliccia, Sveva; Novellino, Ettore; Tron, Gian Cesare
A fast route for the synthesis of tetrazolyl oximes by a novel multicomponent reaction between Z-chlorooximes, isocyanides and trimethylsilyl azide
2017-01-01 Mariateresa, Giustiniano; Sveva, Pelliccia; Ana Belen, Muñoz garcia; Michele, Pavone; Bruno, Pagano; Galli, Ubaldina; Ettore, Novellino; Tron, Gian Cesare
N-N bond formation in Ugi processes: from nitric acid to libraries of nitramines
2017-01-01 Mercalli, Valentina; Nyadanu, Aude; Cordier, Marie; Tron, Gian Cesare; Grimaud, Laurence; El Kaim, Laurent
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Photocatalytic Isocyanide-based Multicomponent Domino Cascade Towards the Stereoselective Formation of Iminofurans | 1-gen-2020 | Pelliccia, Sveva; Alfano, Antonella Ilenia; Luciano, Paolo; Novellino, Ettore; Massarotti, Alberto; Tron, Gian Cesare; Ravelli, Davide; Giustiniano, Mariateresa | |
| Recent Advances in NAMPT Inhibitors: A Novel Immunotherapic Strategy | 1-gen-2020 | Galli, Ubaldina; Colombo, Giorgia; Travelli, Cristina; Tron, Gian Cesare; Genazzani, Armando; Grolla, Ambra | |
| Structure activity relationship studies on Amb639752: toward the identification of a common pharmacophoric structure for DGKα inhibitors | 1-gen-2020 | Velnati, Suresh; Massarotti, Alberto; Antona, Annamaria; Talmon, Maria; Fresu, Luigia Grazia; Galetto, Alessandra Silvia; Capello, Daniela; Bertoni, Alessandra; Mercalli, Valentina; Graziani, Andrea; Tron, Gian Cesare; Baldanzi, Gianluca | |
| Click 1,2,3-triazoles in drug discovery and development: From the flask to the clinic? | 1-gen-2020 | Serafini, M.; Pirali, T.; Tron, G. C. | |
| Visible-Light Photocatalytic Functionalization of Isocyanides for the Synthesis of Secondary Amides and Ketene Aminals | 1-gen-2020 | Cannalire, R.; Amato, J.; Summa, V.; Novellino, E.; Tron, G. C.; Giustiniano, M. | |
| Bio-Inspired Dual-Selective BCL-2/c-MYC G-Quadruplex Binders: Design, Synthesis, and Anticancer Activity of Drug-like Imidazo[2,1-i]purine Derivatives | 1-gen-2020 | Pelliccia, Sveva; Amato, Jussara; Capasso, Domenica; Di Gaetano, Sonia; Massarotti, Alberto; Piccolo, Marialuisa; Irace, Carlo; Tron, Gian Cesare; Pagano, Bruno; Randazzo, Antonio; Novellino, Ettore; Giustiniano, Mariateresa | |
| Metabolic Fate of the Isocyanide Moiety: Are Isocyanides Pharmacophore Groups Neglected by Medicinal Chemists? | 1-gen-2020 | Galli, Ubaldina; Tron, Gian Cesare; Purghè, Beatrice; Grosa, Giorgio; Aprile, Silvio | |
| Nicotinamide Phosphoribosyltransferase (NAMPT) acts as a metabolic gate for mobilization of myeloid-derived suppressor cells | 1-gen-2019 | Travelli, Cristina; Consonni, Francesca Maria; Sangaletti, Sabina; Storto, Mariangela; Morlacchi, Sara; Grolla, Ambra; Galli, Ubaldina; Tron, Gian Cesare; Portararo, Paola; Rimassa, Lorenza; Pressiani, Tiziana; Mazzone, Massimiliano; Trovato, Rosalinda; Ugel, Stefano; Bronte, Vincenzo; Tripodo, Claudio; Colombo, Mario P; Genazzani, Armando; Sica, Antonio | |
| α-Amino Acids as Synthons in the Ugi-5-Centers-4-Components Reaction: Chemistry and Applications | 1-gen-2019 | Pellicia, Sveva; Alfano Ilenia, Antonella; Galli, Ubaldina; Novellino, Ettore; Giustiniano, Mariateresa; Tron, Gian Cesare | |
| Drug Discovery for Soft Drugs on TRPV1 and TRPM8 Channels Using the Passerini Reaction | 1-gen-2019 | Pirali, Tracey; Galli, Ubaldina; Serafini, Marta; Griglio, Alessia; Genazzani, Armando; Tron, Gian Cesare | |
| Exploiting the Nucleophilicity of the Nitrogen Atom of Imidazoles: One-Pot Three-Component Synthesis of Imidazo-Pyrazines | 1-gen-2019 | Galli, Ubaldina; Hysenlika, Rejdia; Meneghetti, Fiorella; Del Grosso, Erika; Pelliccia, Sveva; Novellino, Ettore; Giustiniano, Mariateresa; Tron, Gian Cesare | |
| Aryl Azides as Forgotten Electrophiles in the Van Leusen Reaction: A Multicomponent Transformation Affording 4-Tosyl-1-arylimidazoles | 1-gen-2019 | Necardo, Cristiana; Alfano, Antonella Ilenia; Del Grosso, Erika; Pelliccia, Sveva; Galli, Ubaldina; Novellino, Ettore; Meneghetti, Fiorella; Giustiniano, Mariateresa; Tron, Gian Cesare | |
| Identification of potent triazolylpyridine nicotinamide phosphoribosyltransferase (NAMPT) inhibitors bearing a 1,2,3-triazole tail group | 1-gen-2019 | Travelli, Cristina; Aprile, Silvio; Mattoteia, Daiana; Colombo, Giorgia; Clemente, Nausicaa; Scanziani, Eugenio; Terrazzino, Salvatore; Alisi, Maria Alessandra; Polenzani, Lorenzo; Grosa, Giorgio; Genazzani, Armando; Tron, Gian Cesare; Galli, Ubaldina | |
| Identification of a novel DGKa inhibitor for XLP-1 therapy by virtual screening | 1-gen-2019 | Velnati, Suresh; Ruffo, Elisa; Massarotti, Alberto; Talmon, Maria; Sai Sandeep Varma, Konduru; Gesu, Alessandro; Fresu, Luigia Grazia; Snow, Andrew L.; Bertoni, Alessandra; Capello, Daniela; Tron, Gian Cesare; Graziani, Andrea; Baldanzi, Gianluca | |
| On-water pyrrolidine-mediated domino synthesis of 2-iminoisatins | 1-gen-2018 | Pelliccia, Sveva; Abbate, Vincenzo; Meneghetti, Fiorella; Frascione, Nunzianda; Hider, Robert Charles; Novellino, Ettore; Tron, Gian Cesare; Giustiniano, Mariateresa | |
| Interrupted Ugi and Passerini Reactions: An Underexplored Treasure Island | 1-gen-2018 | Giustiniano, Mariateresa; Moni, Lisa; Sangaletti, Luca; Pelliccia, Sveva; Basso, Andrea; Novellino, Ettore; Tron, Gian Cesare | |
| Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis | 1-gen-2018 | Campa, Carlo C; Silva, Rangel L; Margaria, Jean P; Pirali, Tracey; Mattos, Matheus S; Kraemer, Lucas R; Reis, Diego C; Grosa, Giorgio; Copperi, Francesca; Dalmarco, Eduardo M; Lima-Júnior, Roberto C P; Aprile, Silvio; Sala, Valentina; Dal Bello, Federica; Prado, Douglas Silva; Alves-Filho, Jose Carlos; Medana, Claudio; Cassali, Geovanni D; Tron, Gian Cesare; Teixeira, Mauro M; Ciraolo, Elisa; Russo, Remo C; Hirsch, Emilio | |
| Non-hydrolytic chemoselective cleavage of Ugi tertiary amides: a mild access to N- substituted α-amino acid amides | 1-gen-2018 | Giustiniano, Mariateresa; Pelliccia, Sveva; Novellino, Ettore; Tron, Gian Cesare | |
| A fast route for the synthesis of tetrazolyl oximes by a novel multicomponent reaction between Z-chlorooximes, isocyanides and trimethylsilyl azide | 1-gen-2017 | Mariateresa, Giustiniano; Sveva, Pelliccia; Ana Belen, Muñoz garcia; Michele, Pavone; Bruno, Pagano; Galli, Ubaldina; Ettore, Novellino; Tron, Gian Cesare | |
| N-N bond formation in Ugi processes: from nitric acid to libraries of nitramines | 1-gen-2017 | Mercalli, Valentina; Nyadanu, Aude; Cordier, Marie; Tron, Gian Cesare; Grimaud, Laurence; El Kaim, Laurent |
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