Sfoglia per Autore
An Unexpected Deuterium-Induced Metabolic Switch in Doxophylline
2022-01-01 Aprile, Silvio; Colombo, Giorgia; Serafini, Marta; Di Paola, Rosanna; Pisati, Federica; Bhela, Irene Preet; Cuzzocrea, Salvatore; Grosa, Giorgio; Pirali, Tracey
Data on metabolic stability, aqueous solubility and CYP inhibition of novel triazole-based nicotinamide phosphoribosyltransferase (NAMPT) inhibitors
2020-01-01 Aprile, Silvio; Galli, Ubaldina; Tron, Gian Cesare; Del Grosso, Erika; Travelli, Cristina; Grosa, Giorgio
Metabolic Fate of the Isocyanide Moiety: Are Isocyanides Pharmacophore Groups Neglected by Medicinal Chemists?
2020-01-01 Galli, Ubaldina; Tron, Gian Cesare; Purghè, Beatrice; Grosa, Giorgio; Aprile, Silvio
Preparazioni galeniche Esercizi di tariffazione secondo la nuova TNM
2019-01-01 Morel, Silvia; Grosa, Giorgio
Identification of potent triazolylpyridine nicotinamide phosphoribosyltransferase (NAMPT) inhibitors bearing a 1,2,3-triazole tail group
2019-01-01 Travelli, Cristina; Aprile, Silvio; Mattoteia, Daiana; Colombo, Giorgia; Clemente, Nausicaa; Scanziani, Eugenio; Terrazzino, Salvatore; Alisi, Maria Alessandra; Polenzani, Lorenzo; Grosa, Giorgio; Genazzani, Armando; Tron, Gian Cesare; Galli, Ubaldina
Targeting Transient Receptor Potential Vanilloid 1 (TRPV1) Channel Softly: The Discovery of Passerini Adducts as a Topical Treatment for Inflammatory Skin Disorders
2018-01-01 Serafini, Marta; Griglio, Alessia; Aprile, Silvio; Seiti, Fabio; Travelli, Cristina; Pattarino, Franco; Grosa, Giorgio; Sorba, Giovanni; Genazzani, Armando; Gonzalez-Rodriguez, Sara; Butron, Laura; Devesa, Isabel; Fernandez-Carvajal, Asia; Pirali, Tracey; Ferrer-Montiel, Antonio
Pyrtriazoles, a Novel Class of Store-Operated Calcium Entry Modulators: Discovery, Biological Profiling, and in Vivo Proof-of-Concept Efficacy in Acute Pancreatitis
2018-01-01 Riva, Beatrice; Griglio, Alessia; Serafini, Marta; CORDERO SANCHEZ, Celia; Aprile, Silvio; Di Paola, Rosanna; Gugliandolo, Enrico; Alansary, Dalia; Biocotino, Isabella; Lim, Dmitry; Grosa, Giorgio; Galli, Ubaldina; Niemeyer, Barbara; Sorba, Giovanni; Canonico, Pier Luigi; Cuzzocrea, Salvatore; Genazzani, Armando; Pirali, Tracey
Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis
2018-01-01 Campa, Carlo C; Silva, Rangel L; Margaria, Jean P; Pirali, Tracey; Mattos, Matheus S; Kraemer, Lucas R; Reis, Diego C; Grosa, Giorgio; Copperi, Francesca; Dalmarco, Eduardo M; Lima-Júnior, Roberto C P; Aprile, Silvio; Sala, Valentina; Dal Bello, Federica; Prado, Douglas Silva; Alves-Filho, Jose Carlos; Medana, Claudio; Cassali, Geovanni D; Tron, Gian Cesare; Teixeira, Mauro M; Ciraolo, Elisa; Russo, Remo C; Hirsch, Emilio
Troxerutin, a mixture of O-hydroxyethyl derivatives of the natural flavonoid rutin: Chemical stability and analytical aspects
2018-01-01 Bianchi, Michele; Canavesi, Rossana; Aprile, Silvio; Grosa, Giorgio; Del Grosso, Erika
New insights in the metabolism of oxybutynin: evidence of N-oxidation of propargylamine moiety and rearrangement to enaminoketone
2018-01-01 Aprile, Silvio; Canavesi, Rossana; Matucci, Rosanna; Bellucci, Cristina; DEL GROSSO, Erika; Grosa, Giorgio
Biological effects of combined resveratrol and vitamin D3 on ovarian tissue
2017-01-01 Uberti, Francesca; Morsanuto, Vera; Aprile, Silvio; Ghirlanda, Sabrina; Stoppa, Ian; Cochis, Andrea; Grosa, Giorgio; Rimondini, Lia; Molinari, Claudio Giuseppe
Development and validation of a stability-indicating HPLC-UV method for the determination of Thiocolchicoside and its degradation products
2017-01-01 Aprile, Silvio; Canavesi, Rossana; Bianchi, Michele; Grosa, Giorgio; DEL GROSSO, Erika
Semicarbazide Hydrochloride as Impurity in Drug Substances: a Validated LC-DAD-UV Method for Its Determination in Carbazochrome and Carbazochrome Sodium Sulfonate
2017-01-01 Canavesi, Rossana; Aprile, Silvio; DEL GROSSO, Erika; Grosa, Giorgio
Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity
2017-01-01 Travelli, Cristina; Aprile, Silvio; Rahimian, Reza; Grolla, Ambra A.; Rogati, Federica; Bertolotti, Mattia; Malagnino, Floriana; Di Paola, Rosanna; Impellizzeri, Daniela; Fusco, Roberta; Mercalli, Valentina; Massarotti, Alberto; Stortini, Giorgio; Terrazzino, Salvatore; DEL GROSSO, Erika; Fakhfouri, Gohar; Troiani, Maria Pia; Alisi, Maria Alessandra; Grosa, Giorgio; Sorba, Giovanni; Canonico, Pier Luigi; Orsomando, Giuseppe; Cuzzocrea, Salvatore; Genazzani, Armando; Galli, Ubaldina; Tron, Gian Cesare
Identification of a Potent Phosphoinositide 3-Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs
2017-01-01 Pirali, Tracey; Ciraolo, Elisa; Aprile, Silvio; Massarotti, Alberto; Berndt, Alex; Griglio, Alessia; Serafini, Marta; Mercalli, Valentina; Landoni, Clarissa; Campa, Carlo Cosimo; Margaria, Jean Piero; Silva, Rangel L.; Grosa, Giorgio; Sorba, Giovanni; Williams, Roger; Hirsch, Emilio; Tron, Gian Cesare
CHEMICAL STABILITY STUDIES OF PROPARGYLAMINE-CONTAINING DRUGS
2016-01-01 Canavesi, Rossana; Aprile, Silvio; DEL GROSSO, Erika; Grosa, Giorgio
New insights in oxybutynin chemical stability: Identification in transdermal patches of a new impurity arising from oxybutynin N-oxide rearrangement
2016-01-01 Canavesi, Rossana; Aprile, Silvio; Giovenzana, Giovanni Battista; Di Sotto, Antonella; Di Giacomo, Silvia; DEL GROSSO, Erika; Grosa, Giorgio
CHEMICAL STABILITY STUDIES OF PROPARGYLAMINE CONTAINING-DRUGS
2016-01-01 Canavesi, Rossana; Aprile, Silvio; DEL GROSSO, Erika; Grosa, Giorgio
Design, synthesis, and biological evaluation of combretabenzodiazepines: a novel class of anti-tubulin agents
2015-01-01 Galli, Ubaldina; Travelli, Cristina; Aprile, Silvio; Arrigoni, Elena; Torretta, Simone; Grosa, Giorgio; Massarotti, Alberto; Sorba, Giovanni; Canonico, Pier Luigi; Genazzani, Armando; Tron, Gian Cesare
Development and validation of a stability-indicating LC–UV method for the determination of pantethine and its degradation product based on a forced degradation study
2014-01-01 Canavesi, Rossana; Aprile, Silvio; Elena, Varese; Grosa, Giorgio
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| An Unexpected Deuterium-Induced Metabolic Switch in Doxophylline | 1-gen-2022 | Aprile, Silvio; Colombo, Giorgia; Serafini, Marta; Di Paola, Rosanna; Pisati, Federica; Bhela, Irene Preet; Cuzzocrea, Salvatore; Grosa, Giorgio; Pirali, Tracey | |
| Data on metabolic stability, aqueous solubility and CYP inhibition of novel triazole-based nicotinamide phosphoribosyltransferase (NAMPT) inhibitors | 1-gen-2020 | Aprile, Silvio; Galli, Ubaldina; Tron, Gian Cesare; Del Grosso, Erika; Travelli, Cristina; Grosa, Giorgio | |
| Metabolic Fate of the Isocyanide Moiety: Are Isocyanides Pharmacophore Groups Neglected by Medicinal Chemists? | 1-gen-2020 | Galli, Ubaldina; Tron, Gian Cesare; Purghè, Beatrice; Grosa, Giorgio; Aprile, Silvio | |
| Preparazioni galeniche Esercizi di tariffazione secondo la nuova TNM | 1-gen-2019 | Morel, Silvia; Grosa, Giorgio | |
| Identification of potent triazolylpyridine nicotinamide phosphoribosyltransferase (NAMPT) inhibitors bearing a 1,2,3-triazole tail group | 1-gen-2019 | Travelli, Cristina; Aprile, Silvio; Mattoteia, Daiana; Colombo, Giorgia; Clemente, Nausicaa; Scanziani, Eugenio; Terrazzino, Salvatore; Alisi, Maria Alessandra; Polenzani, Lorenzo; Grosa, Giorgio; Genazzani, Armando; Tron, Gian Cesare; Galli, Ubaldina | |
| Targeting Transient Receptor Potential Vanilloid 1 (TRPV1) Channel Softly: The Discovery of Passerini Adducts as a Topical Treatment for Inflammatory Skin Disorders | 1-gen-2018 | Serafini, Marta; Griglio, Alessia; Aprile, Silvio; Seiti, Fabio; Travelli, Cristina; Pattarino, Franco; Grosa, Giorgio; Sorba, Giovanni; Genazzani, Armando; Gonzalez-Rodriguez, Sara; Butron, Laura; Devesa, Isabel; Fernandez-Carvajal, Asia; Pirali, Tracey; Ferrer-Montiel, Antonio | |
| Pyrtriazoles, a Novel Class of Store-Operated Calcium Entry Modulators: Discovery, Biological Profiling, and in Vivo Proof-of-Concept Efficacy in Acute Pancreatitis | 1-gen-2018 | Riva, Beatrice; Griglio, Alessia; Serafini, Marta; CORDERO SANCHEZ, Celia; Aprile, Silvio; Di Paola, Rosanna; Gugliandolo, Enrico; Alansary, Dalia; Biocotino, Isabella; Lim, Dmitry; Grosa, Giorgio; Galli, Ubaldina; Niemeyer, Barbara; Sorba, Giovanni; Canonico, Pier Luigi; Cuzzocrea, Salvatore; Genazzani, Armando; Pirali, Tracey | |
| Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis | 1-gen-2018 | Campa, Carlo C; Silva, Rangel L; Margaria, Jean P; Pirali, Tracey; Mattos, Matheus S; Kraemer, Lucas R; Reis, Diego C; Grosa, Giorgio; Copperi, Francesca; Dalmarco, Eduardo M; Lima-Júnior, Roberto C P; Aprile, Silvio; Sala, Valentina; Dal Bello, Federica; Prado, Douglas Silva; Alves-Filho, Jose Carlos; Medana, Claudio; Cassali, Geovanni D; Tron, Gian Cesare; Teixeira, Mauro M; Ciraolo, Elisa; Russo, Remo C; Hirsch, Emilio | |
| Troxerutin, a mixture of O-hydroxyethyl derivatives of the natural flavonoid rutin: Chemical stability and analytical aspects | 1-gen-2018 | Bianchi, Michele; Canavesi, Rossana; Aprile, Silvio; Grosa, Giorgio; Del Grosso, Erika | |
| New insights in the metabolism of oxybutynin: evidence of N-oxidation of propargylamine moiety and rearrangement to enaminoketone | 1-gen-2018 | Aprile, Silvio; Canavesi, Rossana; Matucci, Rosanna; Bellucci, Cristina; DEL GROSSO, Erika; Grosa, Giorgio | |
| Biological effects of combined resveratrol and vitamin D3 on ovarian tissue | 1-gen-2017 | Uberti, Francesca; Morsanuto, Vera; Aprile, Silvio; Ghirlanda, Sabrina; Stoppa, Ian; Cochis, Andrea; Grosa, Giorgio; Rimondini, Lia; Molinari, Claudio Giuseppe | |
| Development and validation of a stability-indicating HPLC-UV method for the determination of Thiocolchicoside and its degradation products | 1-gen-2017 | Aprile, Silvio; Canavesi, Rossana; Bianchi, Michele; Grosa, Giorgio; DEL GROSSO, Erika | |
| Semicarbazide Hydrochloride as Impurity in Drug Substances: a Validated LC-DAD-UV Method for Its Determination in Carbazochrome and Carbazochrome Sodium Sulfonate | 1-gen-2017 | Canavesi, Rossana; Aprile, Silvio; DEL GROSSO, Erika; Grosa, Giorgio | |
| Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity | 1-gen-2017 | Travelli, Cristina; Aprile, Silvio; Rahimian, Reza; Grolla, Ambra A.; Rogati, Federica; Bertolotti, Mattia; Malagnino, Floriana; Di Paola, Rosanna; Impellizzeri, Daniela; Fusco, Roberta; Mercalli, Valentina; Massarotti, Alberto; Stortini, Giorgio; Terrazzino, Salvatore; DEL GROSSO, Erika; Fakhfouri, Gohar; Troiani, Maria Pia; Alisi, Maria Alessandra; Grosa, Giorgio; Sorba, Giovanni; Canonico, Pier Luigi; Orsomando, Giuseppe; Cuzzocrea, Salvatore; Genazzani, Armando; Galli, Ubaldina; Tron, Gian Cesare | |
| Identification of a Potent Phosphoinositide 3-Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs | 1-gen-2017 | Pirali, Tracey; Ciraolo, Elisa; Aprile, Silvio; Massarotti, Alberto; Berndt, Alex; Griglio, Alessia; Serafini, Marta; Mercalli, Valentina; Landoni, Clarissa; Campa, Carlo Cosimo; Margaria, Jean Piero; Silva, Rangel L.; Grosa, Giorgio; Sorba, Giovanni; Williams, Roger; Hirsch, Emilio; Tron, Gian Cesare | |
| CHEMICAL STABILITY STUDIES OF PROPARGYLAMINE-CONTAINING DRUGS | 1-gen-2016 | Canavesi, Rossana; Aprile, Silvio; DEL GROSSO, Erika; Grosa, Giorgio | |
| New insights in oxybutynin chemical stability: Identification in transdermal patches of a new impurity arising from oxybutynin N-oxide rearrangement | 1-gen-2016 | Canavesi, Rossana; Aprile, Silvio; Giovenzana, Giovanni Battista; Di Sotto, Antonella; Di Giacomo, Silvia; DEL GROSSO, Erika; Grosa, Giorgio | |
| CHEMICAL STABILITY STUDIES OF PROPARGYLAMINE CONTAINING-DRUGS | 1-gen-2016 | Canavesi, Rossana; Aprile, Silvio; DEL GROSSO, Erika; Grosa, Giorgio | |
| Design, synthesis, and biological evaluation of combretabenzodiazepines: a novel class of anti-tubulin agents | 1-gen-2015 | Galli, Ubaldina; Travelli, Cristina; Aprile, Silvio; Arrigoni, Elena; Torretta, Simone; Grosa, Giorgio; Massarotti, Alberto; Sorba, Giovanni; Canonico, Pier Luigi; Genazzani, Armando; Tron, Gian Cesare | |
| Development and validation of a stability-indicating LC–UV method for the determination of pantethine and its degradation product based on a forced degradation study | 1-gen-2014 | Canavesi, Rossana; Aprile, Silvio; Elena, Varese; Grosa, Giorgio |
Legenda icone
- file ad accesso aperto
- file disponibili sulla rete interna
- file disponibili agli utenti autorizzati
- file disponibili solo agli amministratori
- file sotto embargo
- nessun file disponibile