BHELA, Irene Preet
BHELA, Irene Preet
Dipartimento di Scienze del Farmaco
1,2,4-Oxadiazole-Bearing Pyrazoles as Metabolically Stable Modulators of Store-Operated Calcium Entry
2021-01-01 Aprile, Silvio; Riva, Beatrice; Bhela, Irene Preet; Cordero-Sanchez, Celia; Avino, Giulia; Genazzani, Armando; Serafini, Marta; Pirali, Tracey
A Versatile and Sustainable Multicomponent Platform for the Synthesis of Protein Degraders: Proof-of-Concept Application to BRD4-Degrading PROTACs
2022-01-01 Bhela, Irene Preet; Ranza, Alice; Balestrero, Federica Carolina; Serafini, Marta; Aprile, Silvio; Di Martino, Rita Maria Concetta; Condorelli, Fabrizio; Pirali, Tracey
An Unexpected Deuterium-Induced Metabolic Switch in Doxophylline
2022-01-01 Aprile, Silvio; Colombo, Giorgia; Serafini, Marta; Di Paola, Rosanna; Pisati, Federica; Bhela, Irene Preet; Cuzzocrea, Salvatore; Grosa, Giorgio; Pirali, Tracey
CIC-39Na reverses the thrombocytopenia that characterizes tubular aggregate myopathy
2022-01-01 Cordero-Sanchez, Celia; Pessolano, Emanuela; Riva, Beatrice; Vismara, Mauro; Trivigno, Silvia Maria Grazia; Clemente, Nausicaa; Aprile, Silvio; Ruffinatti, Federico Alessandro; Portararo, Paola; Filigheddu, Nicoletta; Zaggia, Ivan; Bhela, Irene P; Serafini, Marta; Pirali, Tracey; Colombo, Mario P; Torti, Mauro; Sangaletti, Sabina; Bertoni, Alessandra; Genazzani, Armando
STIM1 and ORAI1 mutations leading to tubular aggregate myopathies are sensitive to the Store-operated Ca2+-entry modulators CIC-37 and CIC-39
2022-01-01 Riva, Beatrice; Pessolano, Emanuela; Quaglia, Edoardo; Cordero-Sanchez, Celia; Bhela, Irene P; Topf, Ana; Serafini, Marta; Cox, Daniel; Harris, Elizabeth; Garibaldi, Matteo; Barresi, Rita; Pirali, Tracey; Genazzani, Armando
Store-Operated Calcium Entry as a Therapeutic Target in Acute Pancreatitis: Discovery and Development of Drug-Like SOCE Inhibitors
2020-01-01 Serafini, M.; Cordero Sanchez, C.; Di Paola, R.; Bhela, I. P.; Aprile, S.; Purghe, B.; Fusco, R.; Cuzzocrea, S.; Genazzani, A.; Riva, B.; Pirali, T.
The [1,2,4]Triazolo[4,3-a]pyridine as a New Player in the Field of IDO1 Catalytic Holo-Inhibitors
2021-01-01 Fallarini, S.; Bhela, I. P.; Aprile, S.; Torre, E.; Ranza, A.; Orecchini, E.; Panfili, E.; Pallotta, M. T.; Massarotti, A.; Serafini, M.; Pirali, T.
The multicomponent Passerini reaction as a means of accessing diversity in structure, activity and properties: Soft and hard vanilloid/cannabinoid modulators
2024-01-01 Lamberti, A.; Serafini, M.; Aprile, S.; Bhela, I. P.; Goutsiou, G.; Pessolano, E.; Fernandez-Ballester, G.; Ferrer-Montiel, A.; Di Martino, R. M. C.; Fernandez-Carvajal, A.; Pirali, T.
Tritylamine as an ammonia surrogate in the ugi reaction provides access to unprecedented 5-sulfamido oxazoles using burgess-type reagents
2021-01-01 Bhela, I. P.; Serafini, M.; Del Grosso, E.; Tron, G. C.; Pirali, T.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 1,2,4-Oxadiazole-Bearing Pyrazoles as Metabolically Stable Modulators of Store-Operated Calcium Entry | 1-gen-2021 | Aprile, Silvio; Riva, Beatrice; Bhela, Irene Preet; Cordero-Sanchez, Celia; Avino, Giulia; Genazzani, Armando; Serafini, Marta; Pirali, Tracey | |
| A Versatile and Sustainable Multicomponent Platform for the Synthesis of Protein Degraders: Proof-of-Concept Application to BRD4-Degrading PROTACs | 1-gen-2022 | Bhela, Irene Preet; Ranza, Alice; Balestrero, Federica Carolina; Serafini, Marta; Aprile, Silvio; Di Martino, Rita Maria Concetta; Condorelli, Fabrizio; Pirali, Tracey | |
| An Unexpected Deuterium-Induced Metabolic Switch in Doxophylline | 1-gen-2022 | Aprile, Silvio; Colombo, Giorgia; Serafini, Marta; Di Paola, Rosanna; Pisati, Federica; Bhela, Irene Preet; Cuzzocrea, Salvatore; Grosa, Giorgio; Pirali, Tracey | |
| CIC-39Na reverses the thrombocytopenia that characterizes tubular aggregate myopathy | 1-gen-2022 | Cordero-Sanchez, Celia; Pessolano, Emanuela; Riva, Beatrice; Vismara, Mauro; Trivigno, Silvia Maria Grazia; Clemente, Nausicaa; Aprile, Silvio; Ruffinatti, Federico Alessandro; Portararo, Paola; Filigheddu, Nicoletta; Zaggia, Ivan; Bhela, Irene P; Serafini, Marta; Pirali, Tracey; Colombo, Mario P; Torti, Mauro; Sangaletti, Sabina; Bertoni, Alessandra; Genazzani, Armando | |
| STIM1 and ORAI1 mutations leading to tubular aggregate myopathies are sensitive to the Store-operated Ca2+-entry modulators CIC-37 and CIC-39 | 1-gen-2022 | Riva, Beatrice; Pessolano, Emanuela; Quaglia, Edoardo; Cordero-Sanchez, Celia; Bhela, Irene P; Topf, Ana; Serafini, Marta; Cox, Daniel; Harris, Elizabeth; Garibaldi, Matteo; Barresi, Rita; Pirali, Tracey; Genazzani, Armando | |
| Store-Operated Calcium Entry as a Therapeutic Target in Acute Pancreatitis: Discovery and Development of Drug-Like SOCE Inhibitors | 1-gen-2020 | Serafini, M.; Cordero Sanchez, C.; Di Paola, R.; Bhela, I. P.; Aprile, S.; Purghe, B.; Fusco, R.; Cuzzocrea, S.; Genazzani, A.; Riva, B.; Pirali, T. | |
| The [1,2,4]Triazolo[4,3-a]pyridine as a New Player in the Field of IDO1 Catalytic Holo-Inhibitors | 1-gen-2021 | Fallarini, S.; Bhela, I. P.; Aprile, S.; Torre, E.; Ranza, A.; Orecchini, E.; Panfili, E.; Pallotta, M. T.; Massarotti, A.; Serafini, M.; Pirali, T. | |
| The multicomponent Passerini reaction as a means of accessing diversity in structure, activity and properties: Soft and hard vanilloid/cannabinoid modulators | 1-gen-2024 | Lamberti, A.; Serafini, M.; Aprile, S.; Bhela, I. P.; Goutsiou, G.; Pessolano, E.; Fernandez-Ballester, G.; Ferrer-Montiel, A.; Di Martino, R. M. C.; Fernandez-Carvajal, A.; Pirali, T. | |
| Tritylamine as an ammonia surrogate in the ugi reaction provides access to unprecedented 5-sulfamido oxazoles using burgess-type reagents | 1-gen-2021 | Bhela, I. P.; Serafini, M.; Del Grosso, E.; Tron, G. C.; Pirali, T. |