DONINI, STEFANO
DONINI, STEFANO
Dipartimento di Scienze del Farmaco
Biochemical and structural investigations on phosphoribosylpyrophosphate synthetase from Mycobacterium smegmatis
2017-01-01 Donini, Stefano; Garavaglia, Silvia; Ferraris, DAVIDE MARIA; Miggiano, Riccardo; Mori, Shigetarou; Shibayama, Keigo; Rizzi, Menico
Crystal structure of human aldehyde dehydrogenase 1A3 complexed with NAD+ and retinoic acid
2016-01-01 Moretti, Andrea; Li, Jianfeng; Donini, Stefano; Sobol, Robert W.; Rizzi, Menico; Garavaglia, Silvia
Essential but not vulnerable: indazole sulfonamides targeting inosine monophosphate dehydrogenase as potential leads against Mycobacterium tuberculosis
2016-01-01 Park, Yumi; Pacitto, Angela; Bayliss, Tracy; Cleghorn, Laura A. T; Wang, Zhe; Hartman, Travis; Arora, Kriti; Ioerger, Thomas R; Sacchettini, Jim; Rizzi, Menico; Donini, Stefano; Blundell, Tom L; Ascher, David B; Rhee, Kyu Y; Breda, Ardala; Zhou, Nian; Dartois, Veronique; Jonnala, Surendranadha Reddy; Via, Laura E; Mizrahi, Valerie; Epemolu, Ola; Stojanovski, Laste; Simeons, Frederick Ryan Carne; Osuna Cabello, Maria; Ellis, Lucy; Mackenzie, Claire J; Smith, Alasdair R. C; Davis, Susan Helen; Murugesan, Dinakaran; Buchanan, Kirsteen I; Turner, Penelope A; Huggett, Margaret; Zuccotto, Fabio; Rebollo Lopez, Maria Jose; Lafuente Monasterio, Maria Jose; Sanz, Olalla; Santos Diaz, Gracia; Lelièvre, Joël; Ballell, Lluis; Selenski, Carolyn; Axtman, Matthew; Ghidelli Disse, Sonja; Pflaumer, Hannah; Boesche, Markus; Drewes, Gerard; Freiberg, Gail; Kurnick, Matthew D; Srikumaran, Myron; Kempf, Dale J; Green, Simon R; Ray, Peter Christopher; Read, Kevin D; Wyatt, Paul G; Barry Rd, Clifton E; Boshoff, Helena I. M.
Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis
2017-01-01 Donini, Stefano; Ferraris, DAVIDE MARIA; Miggiano, Riccardo; Massarotti, Alberto; Rizzi, Menico
Synthesis and Structure–Activity relationship of 1-(5-isoquinolinesulfonyl)piperazine analogues as inhibitors of Mycobacterium tuberculosis IMPDH
2019-01-01 Singh, Vinayak; Pacitto, Angela; Donini, Stefano; Ferraris, Davide M.; Boros, Sándor; Illyés, Eszter; Szokol, Bálint; Rizzi, Menico; Blundell, Tom L.; Ascher, David B.; Pato, Janos; Mizrahi, Valerie
The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis
2016-01-01 Singh, Vinayak; Donini, Stefano; Pacitto, Angela; Sala, Claudia; Hartkoorn, Ruben C; Dhar, Neeraj; Keri, Gyorgy; Ascher, David B; Mondésert, Guillaume; Vocat, Anthony; Lupien, Andréanne; Sommer, Raphael; Vermet, Hélène; Lagrange, Sophie; Buechler, Joe; Warner, Digby F; Mckinney, John D; Pato, Janos; Cole, Stewart T; Blundell, Tom L; Rizzi, Menico; Mizrahi, Valerie
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Biochemical and structural investigations on phosphoribosylpyrophosphate synthetase from Mycobacterium smegmatis | 1-gen-2017 | Donini, Stefano; Garavaglia, Silvia; Ferraris, DAVIDE MARIA; Miggiano, Riccardo; Mori, Shigetarou; Shibayama, Keigo; Rizzi, Menico | |
| Crystal structure of human aldehyde dehydrogenase 1A3 complexed with NAD+ and retinoic acid | 1-gen-2016 | Moretti, Andrea; Li, Jianfeng; Donini, Stefano; Sobol, Robert W.; Rizzi, Menico; Garavaglia, Silvia | |
| Essential but not vulnerable: indazole sulfonamides targeting inosine monophosphate dehydrogenase as potential leads against Mycobacterium tuberculosis | 1-gen-2016 | Park, Yumi; Pacitto, Angela; Bayliss, Tracy; Cleghorn, Laura A. T; Wang, Zhe; Hartman, Travis; Arora, Kriti; Ioerger, Thomas R; Sacchettini, Jim; Rizzi, Menico; Donini, Stefano; Blundell, Tom L; Ascher, David B; Rhee, Kyu Y; Breda, Ardala; Zhou, Nian; Dartois, Veronique; Jonnala, Surendranadha Reddy; Via, Laura E; Mizrahi, Valerie; Epemolu, Ola; Stojanovski, Laste; Simeons, Frederick Ryan Carne; Osuna Cabello, Maria; Ellis, Lucy; Mackenzie, Claire J; Smith, Alasdair R. C; Davis, Susan Helen; Murugesan, Dinakaran; Buchanan, Kirsteen I; Turner, Penelope A; Huggett, Margaret; Zuccotto, Fabio; Rebollo Lopez, Maria Jose; Lafuente Monasterio, Maria Jose; Sanz, Olalla; Santos Diaz, Gracia; Lelièvre, Joël; Ballell, Lluis; Selenski, Carolyn; Axtman, Matthew; Ghidelli Disse, Sonja; Pflaumer, Hannah; Boesche, Markus; Drewes, Gerard; Freiberg, Gail; Kurnick, Matthew D; Srikumaran, Myron; Kempf, Dale J; Green, Simon R; Ray, Peter Christopher; Read, Kevin D; Wyatt, Paul G; Barry Rd, Clifton E; Boshoff, Helena I. M. | |
| Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis | 1-gen-2017 | Donini, Stefano; Ferraris, DAVIDE MARIA; Miggiano, Riccardo; Massarotti, Alberto; Rizzi, Menico | |
| Synthesis and Structure–Activity relationship of 1-(5-isoquinolinesulfonyl)piperazine analogues as inhibitors of Mycobacterium tuberculosis IMPDH | 1-gen-2019 | Singh, Vinayak; Pacitto, Angela; Donini, Stefano; Ferraris, Davide M.; Boros, Sándor; Illyés, Eszter; Szokol, Bálint; Rizzi, Menico; Blundell, Tom L.; Ascher, David B.; Pato, Janos; Mizrahi, Valerie | |
| The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis | 1-gen-2016 | Singh, Vinayak; Donini, Stefano; Pacitto, Angela; Sala, Claudia; Hartkoorn, Ruben C; Dhar, Neeraj; Keri, Gyorgy; Ascher, David B; Mondésert, Guillaume; Vocat, Anthony; Lupien, Andréanne; Sommer, Raphael; Vermet, Hélène; Lagrange, Sophie; Buechler, Joe; Warner, Digby F; Mckinney, John D; Pato, Janos; Cole, Stewart T; Blundell, Tom L; Rizzi, Menico; Mizrahi, Valerie |