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Replacement of the double bond of antitubulin chalcones with triazoles and tetrazoles: synthesis and biological evaluation 1-gen-2011 Mesenzani, Ornella; Massarotti, Alberto; Giustiniano, M; Pirali, Tracey; Bevilacqua, V; Caldarelli, Antonio; Canonico, Pier Luigi; Sorba, Giovanni; Novellino, E; Genazzani, Armando; Tron, Gian Cesare
Groebke multicomponent reaction and subsequent nucleophilic aromatic substitution for a convenient synthesis of 3,8-diaminoimidazo[1,2-a]pyrazines as potential kinase inhibitors 1-gen-2011 Guasconi, M; Lu, X; Massarotti, Alberto; Caldarelli, Antonio; Ciraolo, E; Tron, Gian Cesare; Hirsch, E; Sorba, Giovanni; Pirali, Tracey
Essential role of the p110β subunit of phosphoinositide 3-OH kinase in male fertility 1-gen-2010 Ciraolo, Elisa; Morello, Fulvio; Hobbs, ; Robin, M; Wolf, Frieder; Marone, Romina; Iezzi, Manuela; Lu, Xiaoyun; Mengozzi, Giulio; Altruda, Fiorella; Sorba, Giovanni; Giovanni, Guan; Kaomei, Pandolfi; Pier, Paolo; Wymann, ; Matthias, P; Hirsch, Emilio
In search of novel antitubulin agents: synthesis of 1-aryl-5-aroyl tetrazoles by an Ugi 4-CR/hydrogenolysis/transamination reaction 1-gen-2010 Massarotti, Alberto; Giustiniano, M.; Pirali, Tracey; Novellino, E.; Sorba, Giovanni; Tron, Gian Cesare
A novel potent nicotinamide phosphoribosyltransferase inhibitor synthesized via click chemistry 1-gen-2010 Colombano, Giampiero; Travelli, Cristina; Galli, Ubaldina; Caldarelli, Antonio; Chini, Mg; Canonico, Pier Luigi; Sorba, Giovanni; Bifulco, G; Tron, Gian Cesare; Genazzani, Armando
A practical synthesis of 5-aroyl-1-aryltetrazoles using an Ugi-like 4-component reaction followed by a biomimetic transamination 1-gen-2010 Giustiniano, M; Pirali, Tracey; Massarotti, Alberto; Biletta, B; Novellino, E; Campiglia, P; Sorba, Giovanni; Tron, Gian Cesare
“Identification of the first selective Sirt3 inhibitor”, 1-gen-2010 Galli, Ubaldina; C., Coppo; Tron, Gian Cesare; O., Mesenzani; Sorba, Giovanni; P. L., Canonico; A. A., Genazzani
Synthesis and biological evaluation of combretatriazoles 1-gen-2009 Pirali, Tracey; Massarotti, Alberto; DEL GROSSO, Erika; Sorba, Giovanni; Genazzani, Armando; Tron, Gian Cesare
Synthesis, biological evaluation, and molecular docking of Ugi products containing a zinc-chelating moiety as novel inhibitors of histone deacetylase 1-gen-2009 Grolla, Ambra; Podesta, V; Chini, Mg; Di Micco, S; Vallario, A; Genazzani, Armando; Canonico, Pier Luigi; Bifulco, G; Tron, Gian Cesare; Sorba, Giovanni; Pirali, Tracey
Triazole-modified histone deacetylase inhibitors as a rapid route to drug discovery 1-gen-2008 Pirali, Tracey; Pagliai, Francesca; Mercurio, C; Boggio, R; Canonico, Pier Luigi; Sorba, Giovanni; Tron, Gian Cesare; Genazzani, Armando
Solution-phase parallel synthesis and biological evaluation of combretatriazoles 1-gen-2008 Cafici, L; Pirali, Tracey; Condorelli, Fabrizio; DEL GROSSO, Erika; Massarotti, Alberto; Sorba, Giovanni; Canonico, Pier Luigi; Tron, Gian Cesare; Genazzani, Armando
Click chemistry reactions in medicinal chemistry: applications of the 1,3-dipolar cycloaddition between azides and alkynes 1-gen-2008 Tron, Gian Cesare; Pirali, Tracey; Billington, Richard Andrew; Canonico, Pier Luigi; Sorba, Giovanni; Genazzani, Armando
Synthesis and biological evaluation of isosteric analogues of FK866, an inhibitor of NAD salvage 1-gen-2008 Galli, Ubaldina; Ercolano, Emanuela; Carraro, Lorenzo Roberto; Blasi Roman, Cr; Sorba, Giovanni; Canonico, Pier Luigi; Genazzani, Armando; Tron, Gian Cesare; Billington, Richard Andrew
Replacement of the lactone moiety on podophyllotoxin and steganacin analogues with a 1,5-disubstituted 1,2,3-triazole via ruthenium-catalyzed click chemistry 1-gen-2007 Imperio, Daniela; Pirali, Tracey; Galli, Ubaldina; Pagliai, Francesca; Cafici, L; Canonico, Pier Luigi; Sorba, Giovanni; Genazzani, Armando; Tron, Gian Cesare
Molecular Field Analysis and 3D-Quantitative Structure-Activity Relationship Studies (MFA 3D-QSAR) of Bile Acids and Fexaramine Derivatives as Agonists of Farnesoid X Receptor (FXR) 1-gen-2007 Massarotti, Alberto; Macchiarulo, A.; Sorba, Giovanni; Pellicciari, R.
Estrogenic analogues synthesized by click chemistry 1-gen-2007 Pirali, Tracey; Gatti, S; DI BRISCO, R; Tacchi, Sara; Zaninetti, Roberta; Brunelli, Elisa; Massarotti, Alberto; Sorba, Giovanni; Canonico, Pier Luigi; Moro, Laura; Genazzani, Armando; Tron, Gian Cesare; Billington, Richard Andrew
Design, synthesis, and biological evaluation of new (2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-ol ethers as inhibitors of human and Trypanosoma cruzi oxidosqualene cyclase 1-gen-2007 Galli, Ubaldina; Oliaro Bosso, S; Taramino, S; Venegoni, S; Pastore, E; Tron, Gian Cesare; Balliano, G; Viola, F; Sorba, Giovanni
Rapid synthesis of triazole-modified resveratrol analogues via click chemistry 1-gen-2006 Pagliai, F; Pirali, Tracey; DEL GROSSO, Erika; DI BRISCO, R; Tron, Gian Cesare; Sorba, Giovanni; Genazzani, Armando
Medicinal chemistry of combretastatin A4: present and future directions 1-gen-2006 Tron, Gian Cesare; Pirali, Tracey; Sorba, Giovanni; Pagliai, F; Busacca, S; Genazzani, Armando
Synthesis and cytotoxic evaluation of combretafurans, potential scaffolds for dual-action antitumoral agents 1-gen-2006 Pirali, Tracey; Busacca, Sara; Beltrami, L; Imovilli, D; Pagliai, Francesca; Miglio, G; Massarotti, Alberto; Verotta, L; Tron, Gian Cesare; Sorba, Giovanni; Genazzani, Armando
Mostrati risultati da 21 a 40 di 51
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