Sfoglia per Autore
Selective inhibition of indoleamine and tryptophan 2,3-dioxygenases: Comparative study on kynurenine pathway in cell lines via LC-MS/MS-based targeted metabolomics
2024-01-01 Villani, Salvatore; Fallarini, Silvia; Rezzi, Sarah Jane; Di Martino, Rita Maria Concetta; Aprile, Silvio; Del Grosso, Erika
Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold
2023-01-01 De Lorenzi, Ersilia; Seghetti, Francesca; Tarozzi, Andrea; Pruccoli, Letizia; Contardi, Cecilia; Serra, Massimo; Bisi, Alessandra; Gobbi, Silvia; Vistoli, Giulio; Gervasoni, Silvia; Argentini, Carla; Ghirardo, Giulia; Guarato, Giulia; Orso, Genny; Belluti, Federica; Di Martino, Rita Maria Concetta; Zusso, Morena
Deuterium in drug discovery: progress, opportunities and challenges
2023-01-01 Di Martino, R. M. C.; Maxwell, B. D.; Pirali, T.
Dopamine D3 receptor ligands: a patent review (2014-2020)
2022-01-01 DI MARTINO, Rita Maria Concetta; Cavalli, Andrea; Bottegoni, Giovanni
The multitarget FAAH inhibitor/D3 partial agonist ARN15381 decreases nicotine self-administration in male rats
2022-01-01 Lunerti, Veronica; Hongwu, Li; Benvenuti, Federica; Shen, Qianwei; Domi, Ana; Soverchia, Laura; Concetta Di Martino, Rita Maria; Bottegoni, Giovanni; Haass-Koffler, Carolina L; Cannella, Nazzareno
ARN25068, a versatile starting point towards triple GSK-3β/FYN/DYRK1A inhibitors to tackle tau-related neurological disorders
2022-01-01 Demuro, S.; Sauvey, C.; Tripathi, S. K.; Di Martino, R. M. C.; Shi, D.; Ortega, J. A.; Russo, D.; Balboni, B.; Giabbai, B.; Storici, P.; Girotto, S.; Abagyan, R.; Cavalli, A.
A Versatile and Sustainable Multicomponent Platform for the Synthesis of Protein Degraders: Proof-of-Concept Application to BRD4-Degrading PROTACs
2022-01-01 Bhela, Irene Preet; Ranza, Alice; Balestrero, Federica Carolina; Serafini, Marta; Aprile, Silvio; Di Martino, Rita Maria Concetta; Condorelli, Fabrizio; Pirali, Tracey
Modulation of Amyloid β-Induced Microglia Activation and Neuronal Cell Death by Curcumin and Analogues
2022-01-01 De Lorenzi, Ersilia; Franceschini, Davide; Contardi, Cecilia; Di Martino, Rita Maria Concetta; Seghetti, Francesca; Serra, Massimo; Bisceglia, Federica; Pagetta, Andrea; Zusso, Morena; Belluti, Federica
Novel fragment-derived colchicine-site binders as microtubule-destabilizing agents
2022-01-01 de la Roche, Noelia Montel; Mühlethaler, Tobias; Di Martino, Rita Maria Concetta; Ortega, Jose Antonio; Gioia, Dario; Roy, Bibhas; Prota, Andrea E; Steinmetz, Michel O; Cavalli, Andrea
Gsk‐3β, fyn, and dyrk1a: Master regulators in neurodegenerative pathways
2021-01-01 Demuro, S.; Di Martino, R. M. C.; Ortega, J. A.; Cavalli, A.
Curcumin-1,2,3-triazole conjugation for targeting the cancer apoptosis machinery
2020-01-01 Seghetti, F.; Di Martino, R. M. C.; Catanzaro, E.; Bisi, A.; Gobbi, S.; Rampa, A.; Canonico, B.; Montanari, M.; Krysko, D. V.; Papa, S.; Fimognari, C.; Belluti, F.
Novel Curcumin-Diethyl Fumarate Hybrid as a Dualistic GSK-3β Inhibitor/Nrf2 Inducer for the Treatment of Parkinson's Disease
2020-01-01 DI MARTINO, Rita Maria Concetta; Pruccoli, Letizia; Bisi, Alessandra; Gobbi, Silvia; Rampa, Angela; Martinez, Ana; Pérez, Concepción; Martinez-Gonzalez, Loreto; Paglione, Maria; Di Schiavi, Elia; Seghetti, Francesca; Tarozzi, Andrea; Belluti, Federica
Multitarget Compounds for Bipolar Disorder: From Rational Design to Preliminary Pharmacokinetic Evaluation
2020-01-01 Di Martino, R. M. C.; Bottegoni, G.; Seghetti, F.; Russo, D.; Penna, I.; De Simone, A.; Ottonello, G.; Mandrup Bertozzi, S.; Armirotti, A.; Bandiera, T.; Belluti, F.; Cavalli, A.
Investigating Drug-Target Residence Time in Kinases through Enhanced Sampling Simulations
2019-01-01 Gobbo, Dorothea; Piretti, Valentina; Di Martino, R. M. C.; Tripathi, S. K.; Giabbai, B.; Storici, P.; Demitri, N.; Girotto, S.; Decherchi, S.; Cavalli, A.
Identification of chalcone-based antileishmanial agents targeting trypanothione reductase
2018-01-01 Ortalli, Margherita; Ilari, Andrea; Colotti, Gianni; De Ionna, Ilenia; Battista, Theo; Bisi, Alessandra; Gobbi, Silvia; Rampa, Angela; Di Martino, Rita M. C.; Gentilomi, Giovanna A.; Varani, Stefania; Belluti, Federica
Design, Synthesis, Structure-Activity Relationship Studies, and Three-Dimensional Quantitative Structure-Activity Relationship (3D-QSAR) Modeling of a Series of O-Biphenyl Carbamates as Dual Modulators of Dopamine D3 Receptor and Fatty Acid Amide Hydrolase
2017-01-01 De Simone, Alessio; Russo, Debora; Ruda, Gian Filippo; Micoli, Alessandra; Ferraro, Mariarosaria; Di Martino, Rita Maria Concetta; Ottonello, Giuliana; Summa, Maria; Armirotti, Andrea; Bandiera, Tiziano; Cavalli, Andrea; Bottegoni, Giovanni
Coumarin derivatives as potential antitumor agents: Growth inhibition, apoptosis induction and multidrug resistance reverting activity
2017-01-01 Bisi, Alessandra; Cappadone, Concettina; Rampa, Angela; Farruggia, Giovanna; Sargenti, Azzurra; Belluti, Federica; Di Martino, Rita Maria Concetta; Malucelli, Emil; Meluzzi, Alessia; Iotti, Stefano; Gobbi, Silvia
Recent progress on curcumin-based therapeutics: a patent review (2012-2016). Part I: Curcumin
2017-01-01 DI MARTINO, RITA MARIA CONCETTA; Luppi, Barbara; Bisi, Alessandra; Gobbi, Silvia; Rampa, Angela; Abruzzo, Angela; Belluti, Federica
Phenolic 1,3-diketones attenuate lipopolysaccharide-induced inflammatory response by an alternative magnesium-mediated mechanism
2017-01-01 Zusso, Morena; Mercanti, Giulia; Belluti, Federica; Di Martino, Rita Maria Concetta; Pagetta, Andrea; Marinelli, Carla; Brun, Paola; Ragazzi, Eugenio; Lo, Rita; Stifani, Stefano; Giusti, Pietro; Moro, Stefano
Dual BACE-1/GSK-3β Inhibitors to Combat Alzheimer's Disease: A Focused Review
2017-01-01 Rampa, Angela; Gobbi, Silvia; Concetta Di Martino, Rita Maria; Belluti, Federica; Bisi, Alessandra
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Selective inhibition of indoleamine and tryptophan 2,3-dioxygenases: Comparative study on kynurenine pathway in cell lines via LC-MS/MS-based targeted metabolomics | 1-gen-2024 | Villani, Salvatore; Fallarini, Silvia; Rezzi, Sarah Jane; Di Martino, Rita Maria Concetta; Aprile, Silvio; Del Grosso, Erika | |
| Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold | 1-gen-2023 | De Lorenzi, Ersilia; Seghetti, Francesca; Tarozzi, Andrea; Pruccoli, Letizia; Contardi, Cecilia; Serra, Massimo; Bisi, Alessandra; Gobbi, Silvia; Vistoli, Giulio; Gervasoni, Silvia; Argentini, Carla; Ghirardo, Giulia; Guarato, Giulia; Orso, Genny; Belluti, Federica; Di Martino, Rita Maria Concetta; Zusso, Morena | |
| Deuterium in drug discovery: progress, opportunities and challenges | 1-gen-2023 | Di Martino, R. M. C.; Maxwell, B. D.; Pirali, T. | |
| Dopamine D3 receptor ligands: a patent review (2014-2020) | 1-gen-2022 | DI MARTINO, Rita Maria Concetta; Cavalli, Andrea; Bottegoni, Giovanni | |
| The multitarget FAAH inhibitor/D3 partial agonist ARN15381 decreases nicotine self-administration in male rats | 1-gen-2022 | Lunerti, Veronica; Hongwu, Li; Benvenuti, Federica; Shen, Qianwei; Domi, Ana; Soverchia, Laura; Concetta Di Martino, Rita Maria; Bottegoni, Giovanni; Haass-Koffler, Carolina L; Cannella, Nazzareno | |
| ARN25068, a versatile starting point towards triple GSK-3β/FYN/DYRK1A inhibitors to tackle tau-related neurological disorders | 1-gen-2022 | Demuro, S.; Sauvey, C.; Tripathi, S. K.; Di Martino, R. M. C.; Shi, D.; Ortega, J. A.; Russo, D.; Balboni, B.; Giabbai, B.; Storici, P.; Girotto, S.; Abagyan, R.; Cavalli, A. | |
| A Versatile and Sustainable Multicomponent Platform for the Synthesis of Protein Degraders: Proof-of-Concept Application to BRD4-Degrading PROTACs | 1-gen-2022 | Bhela, Irene Preet; Ranza, Alice; Balestrero, Federica Carolina; Serafini, Marta; Aprile, Silvio; Di Martino, Rita Maria Concetta; Condorelli, Fabrizio; Pirali, Tracey | |
| Modulation of Amyloid β-Induced Microglia Activation and Neuronal Cell Death by Curcumin and Analogues | 1-gen-2022 | De Lorenzi, Ersilia; Franceschini, Davide; Contardi, Cecilia; Di Martino, Rita Maria Concetta; Seghetti, Francesca; Serra, Massimo; Bisceglia, Federica; Pagetta, Andrea; Zusso, Morena; Belluti, Federica | |
| Novel fragment-derived colchicine-site binders as microtubule-destabilizing agents | 1-gen-2022 | de la Roche, Noelia Montel; Mühlethaler, Tobias; Di Martino, Rita Maria Concetta; Ortega, Jose Antonio; Gioia, Dario; Roy, Bibhas; Prota, Andrea E; Steinmetz, Michel O; Cavalli, Andrea | |
| Gsk‐3β, fyn, and dyrk1a: Master regulators in neurodegenerative pathways | 1-gen-2021 | Demuro, S.; Di Martino, R. M. C.; Ortega, J. A.; Cavalli, A. | |
| Curcumin-1,2,3-triazole conjugation for targeting the cancer apoptosis machinery | 1-gen-2020 | Seghetti, F.; Di Martino, R. M. C.; Catanzaro, E.; Bisi, A.; Gobbi, S.; Rampa, A.; Canonico, B.; Montanari, M.; Krysko, D. V.; Papa, S.; Fimognari, C.; Belluti, F. | |
| Novel Curcumin-Diethyl Fumarate Hybrid as a Dualistic GSK-3β Inhibitor/Nrf2 Inducer for the Treatment of Parkinson's Disease | 1-gen-2020 | DI MARTINO, Rita Maria Concetta; Pruccoli, Letizia; Bisi, Alessandra; Gobbi, Silvia; Rampa, Angela; Martinez, Ana; Pérez, Concepción; Martinez-Gonzalez, Loreto; Paglione, Maria; Di Schiavi, Elia; Seghetti, Francesca; Tarozzi, Andrea; Belluti, Federica | |
| Multitarget Compounds for Bipolar Disorder: From Rational Design to Preliminary Pharmacokinetic Evaluation | 1-gen-2020 | Di Martino, R. M. C.; Bottegoni, G.; Seghetti, F.; Russo, D.; Penna, I.; De Simone, A.; Ottonello, G.; Mandrup Bertozzi, S.; Armirotti, A.; Bandiera, T.; Belluti, F.; Cavalli, A. | |
| Investigating Drug-Target Residence Time in Kinases through Enhanced Sampling Simulations | 1-gen-2019 | Gobbo, Dorothea; Piretti, Valentina; Di Martino, R. M. C.; Tripathi, S. K.; Giabbai, B.; Storici, P.; Demitri, N.; Girotto, S.; Decherchi, S.; Cavalli, A. | |
| Identification of chalcone-based antileishmanial agents targeting trypanothione reductase | 1-gen-2018 | Ortalli, Margherita; Ilari, Andrea; Colotti, Gianni; De Ionna, Ilenia; Battista, Theo; Bisi, Alessandra; Gobbi, Silvia; Rampa, Angela; Di Martino, Rita M. C.; Gentilomi, Giovanna A.; Varani, Stefania; Belluti, Federica | |
| Design, Synthesis, Structure-Activity Relationship Studies, and Three-Dimensional Quantitative Structure-Activity Relationship (3D-QSAR) Modeling of a Series of O-Biphenyl Carbamates as Dual Modulators of Dopamine D3 Receptor and Fatty Acid Amide Hydrolase | 1-gen-2017 | De Simone, Alessio; Russo, Debora; Ruda, Gian Filippo; Micoli, Alessandra; Ferraro, Mariarosaria; Di Martino, Rita Maria Concetta; Ottonello, Giuliana; Summa, Maria; Armirotti, Andrea; Bandiera, Tiziano; Cavalli, Andrea; Bottegoni, Giovanni | |
| Coumarin derivatives as potential antitumor agents: Growth inhibition, apoptosis induction and multidrug resistance reverting activity | 1-gen-2017 | Bisi, Alessandra; Cappadone, Concettina; Rampa, Angela; Farruggia, Giovanna; Sargenti, Azzurra; Belluti, Federica; Di Martino, Rita Maria Concetta; Malucelli, Emil; Meluzzi, Alessia; Iotti, Stefano; Gobbi, Silvia | |
| Recent progress on curcumin-based therapeutics: a patent review (2012-2016). Part I: Curcumin | 1-gen-2017 | DI MARTINO, RITA MARIA CONCETTA; Luppi, Barbara; Bisi, Alessandra; Gobbi, Silvia; Rampa, Angela; Abruzzo, Angela; Belluti, Federica | |
| Phenolic 1,3-diketones attenuate lipopolysaccharide-induced inflammatory response by an alternative magnesium-mediated mechanism | 1-gen-2017 | Zusso, Morena; Mercanti, Giulia; Belluti, Federica; Di Martino, Rita Maria Concetta; Pagetta, Andrea; Marinelli, Carla; Brun, Paola; Ragazzi, Eugenio; Lo, Rita; Stifani, Stefano; Giusti, Pietro; Moro, Stefano | |
| Dual BACE-1/GSK-3β Inhibitors to Combat Alzheimer's Disease: A Focused Review | 1-gen-2017 | Rampa, Angela; Gobbi, Silvia; Concetta Di Martino, Rita Maria; Belluti, Federica; Bisi, Alessandra |
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