Sfoglia per Autore
A Versatile and Sustainable Multicomponent Platform for the Synthesis of Protein Degraders: Proof-of-Concept Application to BRD4-Degrading PROTACs
2022-01-01 Bhela, Irene Preet; Ranza, Alice; Balestrero, Federica Carolina; Serafini, Marta; Aprile, Silvio; Di Martino, Rita Maria Concetta; Condorelli, Fabrizio; Pirali, Tracey
STIM1 and ORAI1 mutations leading to tubular aggregate myopathies are sensitive to the Store-operated Ca2+-entry modulators CIC-37 and CIC-39
2022-01-01 Riva, Beatrice; Pessolano, Emanuela; Quaglia, Edoardo; Cordero-Sanchez, Celia; Bhela, Irene P; Topf, Ana; Serafini, Marta; Cox, Daniel; Harris, Elizabeth; Garibaldi, Matteo; Barresi, Rita; Pirali, Tracey; Genazzani, Armando
CIC-39Na reverses the thrombocytopenia that characterizes tubular aggregate myopathy
2022-01-01 Cordero-Sanchez, Celia; Pessolano, Emanuela; Riva, Beatrice; Vismara, Mauro; Trivigno, Silvia Maria Grazia; Clemente, Nausicaa; Aprile, Silvio; Ruffinatti, Federico Alessandro; Portararo, Paola; Filigheddu, Nicoletta; Zaggia, Ivan; Bhela, Irene P; Serafini, Marta; Pirali, Tracey; Colombo, Mario P; Torti, Mauro; Sangaletti, Sabina; Bertoni, Alessandra; Genazzani, Armando
An Unexpected Deuterium-Induced Metabolic Switch in Doxophylline
2022-01-01 Aprile, Silvio; Colombo, Giorgia; Serafini, Marta; Di Paola, Rosanna; Pisati, Federica; Bhela, Irene Preet; Cuzzocrea, Salvatore; Grosa, Giorgio; Pirali, Tracey
What's in a Name? Drug Nomenclature and Medicinal Chemistry Trends using INN Publications
2021-01-01 Serafini, M.; Cargnin, S.; Massarotti, A.; Tron, G. C.; Pirali, T.; Genazzani, A.
Tritylamine as an ammonia surrogate in the ugi reaction provides access to unprecedented 5-sulfamido oxazoles using burgess-type reagents
2021-01-01 Bhela, I. P.; Serafini, M.; Del Grosso, E.; Tron, G. C.; Pirali, T.
Discovery and development of small molecules targeting IDO1 and SOCE
2021-01-01 Serafini, Marta
The [1,2,4]Triazolo[4,3-a]pyridine as a New Player in the Field of IDO1 Catalytic Holo-Inhibitors
2021-01-01 Fallarini, S.; Bhela, I. P.; Aprile, S.; Torre, E.; Ranza, A.; Orecchini, E.; Panfili, E.; Pallotta, M. T.; Massarotti, A.; Serafini, M.; Pirali, T.
The 115 Year Old Multicomponent Bargellini Reaction: Perspectives and New Applications
2021-01-01 Serafini, Marta; Murgia, Ilaria; Giustiniano, Mariateresa; Pirali, Tracey; Tron, Gian Cesare
A capsaicinoid-based soft drug, AG1529, for attenuating TRPV1-mediated histaminergic and inflammatory sensory neuron excitability
2021-01-01 Nikolaeva-Koleva, M.; Butron, L.; Gonzalez-Rodriguez, S.; Devesa, I.; Valente, P.; Serafini, M.; Genazzani, A.; Pirali, T.; Ballester, G. F.; Fernandez-Carvajal, A.; Ferrer-Montiel, A.
1,2,4-Oxadiazole-Bearing Pyrazoles as Metabolically Stable Modulators of Store-Operated Calcium Entry
2021-01-01 Aprile, Silvio; Riva, Beatrice; Bhela, Irene Preet; Cordero-Sanchez, Celia; Avino, Giulia; Genazzani, Armando; Serafini, Marta; Pirali, Tracey
Click 1,2,3-triazoles in drug discovery and development: From the flask to the clinic?
2020-01-01 Serafini, M.; Pirali, T.; Tron, G. C.
Store-Operated Calcium Entry as a Therapeutic Target in Acute Pancreatitis: Discovery and Development of Drug-Like SOCE Inhibitors
2020-01-01 Serafini, M.; Cordero Sanchez, C.; Di Paola, R.; Bhela, I. P.; Aprile, S.; Purghe, B.; Fusco, R.; Cuzzocrea, S.; Genazzani, A.; Riva, B.; Pirali, T.
Discovery of Highly Potent Benzimidazole Derivatives as Indoleamine 2,3-Dioxygenase-1 (IDO1) Inhibitors: From Structure-Based Virtual Screening to in Vivo Pharmacodynamic Activity
2020-01-01 Serafini, M.; Torre, E.; Aprile, S.; Del Grosso, E.; Gesu, A.; Griglio, A.; Colombo, G.; Travelli, C.; Paiella, S.; Adamo, A.; Orecchini, E.; Coletti, A.; Pallotta, M. T.; Ugel, S.; Massarotti, A.; Pirali, T.; Fallarini, S.
The Essential Medicinal Chemistry of Essential Medicines
2020-01-01 Serafini, Marta; Cargnin, Sarah; Massarotti, Alberto; Pirali, Tracey; Genazzani, Armando
A primer of deuterium in drug design
2019-01-01 Cargnin, Sarah; Serafini, Marta; Pirali, Tracey
Soft drugs for dermatological applications: recent trends
2019-01-01 Aprile, Silvio; Serafini, Marta; Pirali, Tracey
Applications of deuterium in medicinal chemistry
2019-01-01 Pirali, Tracey; Serafini, Marta; Cargnin, Sarah; Genazzani, Armando
SOCE: EMERGE UN NUOVO TARGET TERAPEUTICO DAL “CALCIUM TOOLKIT” DELLA CELLULA
2019-01-01 Serafini, Marta; Pirali, Tracey
Synthesis, Docking and Biological Evaluation of a Novel Class of Imidazothiazoles as IDO1 Inhibitors
2019-01-01 Serafini, Marta; Torre, Enza; Aprile, Silvio; Massarotti, Alberto; Fallarini, Silvia; Pirali, Tracey
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A Versatile and Sustainable Multicomponent Platform for the Synthesis of Protein Degraders: Proof-of-Concept Application to BRD4-Degrading PROTACs | 1-gen-2022 | Bhela, Irene Preet; Ranza, Alice; Balestrero, Federica Carolina; Serafini, Marta; Aprile, Silvio; Di Martino, Rita Maria Concetta; Condorelli, Fabrizio; Pirali, Tracey | |
| STIM1 and ORAI1 mutations leading to tubular aggregate myopathies are sensitive to the Store-operated Ca2+-entry modulators CIC-37 and CIC-39 | 1-gen-2022 | Riva, Beatrice; Pessolano, Emanuela; Quaglia, Edoardo; Cordero-Sanchez, Celia; Bhela, Irene P; Topf, Ana; Serafini, Marta; Cox, Daniel; Harris, Elizabeth; Garibaldi, Matteo; Barresi, Rita; Pirali, Tracey; Genazzani, Armando | |
| CIC-39Na reverses the thrombocytopenia that characterizes tubular aggregate myopathy | 1-gen-2022 | Cordero-Sanchez, Celia; Pessolano, Emanuela; Riva, Beatrice; Vismara, Mauro; Trivigno, Silvia Maria Grazia; Clemente, Nausicaa; Aprile, Silvio; Ruffinatti, Federico Alessandro; Portararo, Paola; Filigheddu, Nicoletta; Zaggia, Ivan; Bhela, Irene P; Serafini, Marta; Pirali, Tracey; Colombo, Mario P; Torti, Mauro; Sangaletti, Sabina; Bertoni, Alessandra; Genazzani, Armando | |
| An Unexpected Deuterium-Induced Metabolic Switch in Doxophylline | 1-gen-2022 | Aprile, Silvio; Colombo, Giorgia; Serafini, Marta; Di Paola, Rosanna; Pisati, Federica; Bhela, Irene Preet; Cuzzocrea, Salvatore; Grosa, Giorgio; Pirali, Tracey | |
| What's in a Name? Drug Nomenclature and Medicinal Chemistry Trends using INN Publications | 1-gen-2021 | Serafini, M.; Cargnin, S.; Massarotti, A.; Tron, G. C.; Pirali, T.; Genazzani, A. | |
| Tritylamine as an ammonia surrogate in the ugi reaction provides access to unprecedented 5-sulfamido oxazoles using burgess-type reagents | 1-gen-2021 | Bhela, I. P.; Serafini, M.; Del Grosso, E.; Tron, G. C.; Pirali, T. | |
| Discovery and development of small molecules targeting IDO1 and SOCE | 1-gen-2021 | Serafini, Marta | |
| The [1,2,4]Triazolo[4,3-a]pyridine as a New Player in the Field of IDO1 Catalytic Holo-Inhibitors | 1-gen-2021 | Fallarini, S.; Bhela, I. P.; Aprile, S.; Torre, E.; Ranza, A.; Orecchini, E.; Panfili, E.; Pallotta, M. T.; Massarotti, A.; Serafini, M.; Pirali, T. | |
| The 115 Year Old Multicomponent Bargellini Reaction: Perspectives and New Applications | 1-gen-2021 | Serafini, Marta; Murgia, Ilaria; Giustiniano, Mariateresa; Pirali, Tracey; Tron, Gian Cesare | |
| A capsaicinoid-based soft drug, AG1529, for attenuating TRPV1-mediated histaminergic and inflammatory sensory neuron excitability | 1-gen-2021 | Nikolaeva-Koleva, M.; Butron, L.; Gonzalez-Rodriguez, S.; Devesa, I.; Valente, P.; Serafini, M.; Genazzani, A.; Pirali, T.; Ballester, G. F.; Fernandez-Carvajal, A.; Ferrer-Montiel, A. | |
| 1,2,4-Oxadiazole-Bearing Pyrazoles as Metabolically Stable Modulators of Store-Operated Calcium Entry | 1-gen-2021 | Aprile, Silvio; Riva, Beatrice; Bhela, Irene Preet; Cordero-Sanchez, Celia; Avino, Giulia; Genazzani, Armando; Serafini, Marta; Pirali, Tracey | |
| Click 1,2,3-triazoles in drug discovery and development: From the flask to the clinic? | 1-gen-2020 | Serafini, M.; Pirali, T.; Tron, G. C. | |
| Store-Operated Calcium Entry as a Therapeutic Target in Acute Pancreatitis: Discovery and Development of Drug-Like SOCE Inhibitors | 1-gen-2020 | Serafini, M.; Cordero Sanchez, C.; Di Paola, R.; Bhela, I. P.; Aprile, S.; Purghe, B.; Fusco, R.; Cuzzocrea, S.; Genazzani, A.; Riva, B.; Pirali, T. | |
| Discovery of Highly Potent Benzimidazole Derivatives as Indoleamine 2,3-Dioxygenase-1 (IDO1) Inhibitors: From Structure-Based Virtual Screening to in Vivo Pharmacodynamic Activity | 1-gen-2020 | Serafini, M.; Torre, E.; Aprile, S.; Del Grosso, E.; Gesu, A.; Griglio, A.; Colombo, G.; Travelli, C.; Paiella, S.; Adamo, A.; Orecchini, E.; Coletti, A.; Pallotta, M. T.; Ugel, S.; Massarotti, A.; Pirali, T.; Fallarini, S. | |
| The Essential Medicinal Chemistry of Essential Medicines | 1-gen-2020 | Serafini, Marta; Cargnin, Sarah; Massarotti, Alberto; Pirali, Tracey; Genazzani, Armando | |
| A primer of deuterium in drug design | 1-gen-2019 | Cargnin, Sarah; Serafini, Marta; Pirali, Tracey | |
| Soft drugs for dermatological applications: recent trends | 1-gen-2019 | Aprile, Silvio; Serafini, Marta; Pirali, Tracey | |
| Applications of deuterium in medicinal chemistry | 1-gen-2019 | Pirali, Tracey; Serafini, Marta; Cargnin, Sarah; Genazzani, Armando | |
| SOCE: EMERGE UN NUOVO TARGET TERAPEUTICO DAL “CALCIUM TOOLKIT” DELLA CELLULA | 1-gen-2019 | Serafini, Marta; Pirali, Tracey | |
| Synthesis, Docking and Biological Evaluation of a Novel Class of Imidazothiazoles as IDO1 Inhibitors | 1-gen-2019 | Serafini, Marta; Torre, Enza; Aprile, Silvio; Massarotti, Alberto; Fallarini, Silvia; Pirali, Tracey |
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