Sfoglia per Autore
An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent
2024-01-01 Alberti, Marta; Poli, Giulio; Broggini, Luca; Sainas, Stefano; Rizzi, Menico; Boschi, Donatella; Ferraris, Davide M; Martino, Elena; Ricagno, Stefano; Tuccinardi, Tiziano; Lolli, Marco L; Miggiano, Riccardo
Identification of a Compound Inhibiting Both the Enzymatic and Nonenzymatic Functions of Indoleamine 2,3-Dioxygenase 1
2024-01-01 Panfili, Eleonora; Rezzi, Sarah Jane; Adamo, Annalisa; Mazzoletti, Daniele; Massarotti, Alberto; Miggiano, Riccardo; Fallarini, Silvia; Ambrosino, Sara; Coletti, Alice; Molinaro, Pasquale; Milella, Michele; Paiella, Salvatore; Macchiarulo, Antonio; Ugel, Stefano; Pirali, Tracey; Pallotta, Maria Teresa
ER-mitochondria distance is a critical parameter for efficient mitochondrial Ca2+ uptake and oxidative metabolism
2024-01-01 Dematteis, G.; Tapella, L.; Casali, C.; Talmon, M.; Tonelli, E.; Reano, S.; Ariotti, A.; Pessolano, E.; Malecka, J.; Chrostek, G.; Kulkoviene, G.; Umbrasas, D.; Distasi, C.; Grilli, M.; Ladds, G.; Filigheddu, N.; Fresu, L. G.; Mikoshiba, K.; Matute, C.; Ramos-Gonzalez, P.; Jekabsone, A.; Cali, T.; Brini, M.; Biggiogera, M.; Cavaliere, F.; Miggiano, R.; Genazzani, A. A.; Lim, D.
Cryo-EM-based structural investigation of Mycobacterium tuberculosis Nucleotide Excision Repair
2023-01-01 Genta, Marianna; Chaves, Antonio; Bolognesi, Martino; Rossi, Franca; Rizzi, Menico; Miggiano, Riccardo
Cryo-EM-based structural investigation of Mycobacterium tuberculosis Nucleotide Excision Repair
2023-01-01 Genta, Marianna; Chaves, Antonio; Bolognesi, Martino; Rossi, Franca; Rizzi, Menico; Miggiano, Riccardo
Nucleotide Excision Repair in Mycobacterium tuberculosis: a Cryo-EM snapshot of the damage recognition process
2023-01-01 Genta, Marianna; Chaves, Antonio; Bolognesi, Martino; Rossi, Franca; Rizzi, Menico; Miggiano, Riccardo
Biochemical characterization of Mycobacterium tuberculosis dihydroorotate dehydrogenase and identification of a selective inhibitor
2023-01-01 Alberti, Marta; Sainas, Stefano; Ronchi, Erika; Lolli, Marco L; Boschi, Donatella; Rizzi, Menico; Ferraris, Davide M; Miggiano, Riccardo
The integration of AlphaFold-predicted and crystal structures of human trans-3-hydroxy-l-proline dehydratase reveals a regulatory catalytic mechanism
2022-01-01 Ferrario, Eugenio; Miggiano, Riccardo; Rizzi, Menico; Ferraris, Davide M
Biochemical and structural analysis of a cytosolic sulfotransferase of the malaria vector Anopheles gambiae overexpressed in the reproductive tissues
2022-01-01 Esposito Verza, Arianna; Miggiano, Riccardo; Lombardo, Fabrizio; Fiorillo, Carmine; Arcà, Bruno; Purghé, Beatrice; Del Grosso, Erika; Galli, Ubaldina; Rizzi, Menico; Rossi, Franca
First thermostable CLIP-tag by rational design applied to an archaeal O6-alkyl-guanine-DNA-alkyl-transferase
2022-01-01 Merlo, R.; Mattossovich, R.; Genta, M.; Valenti, A.; Di Mauro, G.; Minassi, A.; Miggiano, R.; Perugino, G.
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Aryloxyaryl Moiety
2022-01-01 Sainas, Stefano; Giorgis, Marta; Circosta, Paola; Poli, Giulio; Alberti, Marta; Passoni, Alice; Gaidano, Valentina; Pippione, Agnese C; Vitale, Nicoletta; Bonanni, Davide; Rolando, Barbara; Cignetti, Alessandro; Ramondetti, Cristina; Lanno, Alessia; Ferraris, Davide M; Canepa, Barbara; Buccinnà, Barbara; Piccinini, Marco; Rizzi, Menico; Saglio, Giuseppe; Al-Karadaghi, Salam; Boschi, Donatella; Miggiano, Riccardo; Tuccinardi, Tiziano; Lolli, Marco L
Engineering, Characterization, and Biological Evaluation of an Antibody Targeting the HGF Receptor
2021-01-01 Desole, C.; Gallo, S.; Vitacolonna, A.; Vigna, E.; Basilico, C.; Montarolo, F.; Zuppini, F.; Casanova, E.; Miggiano, R.; Ferraris, D. M.; Bertolotto, A.; Comoglio, P. M.; Crepaldi, T.
The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate
2021-01-01 Merlo, R.; Caprioglio, D.; Cillo, M.; Valenti, A.; Mattossovich, R.; Morrone, C.; Massarotti, A.; Rossi, F.; Miggiano, R.; Leonardi, A.; Minassi, A.; Perugino, G.
Crystal structure of Haemophilus influenzae 3-isopropylmalate dehydrogenase (LeuB) in complex with the inhibitor O-isobutenyl oxalylhydroxamate
2020-01-01 Miggiano, R.; Martignon, S.; Minassi, A.; Rossi, F.; Rizzi, M.
O6-alkylguanine-DNA Alkyltransferases in Microbes Living on the Edge: From Stability to Applicability
2020-01-01 Mattossovich, Rosanna; Merlo, Rosa; Miggiano, Riccardo; Valenti, Anna; Perugino, Giuseppe
Toll-like receptor 4-mediated inflammation triggered by extracellular IFI16 is enhanced by lipopolysaccharide binding
2020-01-01 Iannucci, A.; Caneparo, V.; Raviola, S.; Debernardi, I.; Colangelo, D.; Miggiano, R.; Griffante, G.; Landolfo, S.; Gariglio, M.; de Andrea, M.
A nicotinamide phosphoribosyltransferase–GAPDH interaction sustains the stress-induced NMN/NAD+ salvage pathway in the nucleus
2020-01-01 Grolla, Ambra; Miggiano, Riccardo; Di Marino, Daniele; Bianchi, Michele; Gori, Alessandro; Orsomando, Giuseppe; Gaudino, Federica; Galli, Ubaldina; Del Grosso, Erika; Mazzola, Francesca; Angeletti, Carlo; Guarneri, Martina; Torretta, Simone; Calabrò, Marta; Boumya, Sara; Fan, Xiaorui; Colombo, Giorgia; Travelli, Cristina; Rocchio, Francesca; Aronica, Eleonora; Wohlschlegel, James A; Deaglio, Silvia; Rizzi, Menico; Genazzani, Armando; Garavaglia, Silvia
Structure of Thermococcus litoralis Δ1-pyrroline-2-carboxylate reductase in complex with NADH and L-proline
2020-01-01 Ferrario, Eugenio; Miggiano, Riccardo; Rizzi, Menico; Ferraris, Davide M
Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment
2020-01-01 Miggiano, Riccardo; Rizzi, Menico; Ferraris, Davide M.
Targeting Genome Integrity in Mycobacterium Tuberculosis: From Nucleotide Synthesis to DNA Replication and Repair
2020-01-01 Miggiano, Riccardo; Morrone, Castrese; Rossi, Franca; Rizzi, Menico
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent | 1-gen-2024 | Alberti, Marta; Poli, Giulio; Broggini, Luca; Sainas, Stefano; Rizzi, Menico; Boschi, Donatella; Ferraris, Davide M; Martino, Elena; Ricagno, Stefano; Tuccinardi, Tiziano; Lolli, Marco L; Miggiano, Riccardo | |
Identification of a Compound Inhibiting Both the Enzymatic and Nonenzymatic Functions of Indoleamine 2,3-Dioxygenase 1 | 1-gen-2024 | Panfili, Eleonora; Rezzi, Sarah Jane; Adamo, Annalisa; Mazzoletti, Daniele; Massarotti, Alberto; Miggiano, Riccardo; Fallarini, Silvia; Ambrosino, Sara; Coletti, Alice; Molinaro, Pasquale; Milella, Michele; Paiella, Salvatore; Macchiarulo, Antonio; Ugel, Stefano; Pirali, Tracey; Pallotta, Maria Teresa | |
ER-mitochondria distance is a critical parameter for efficient mitochondrial Ca2+ uptake and oxidative metabolism | 1-gen-2024 | Dematteis, G.; Tapella, L.; Casali, C.; Talmon, M.; Tonelli, E.; Reano, S.; Ariotti, A.; Pessolano, E.; Malecka, J.; Chrostek, G.; Kulkoviene, G.; Umbrasas, D.; Distasi, C.; Grilli, M.; Ladds, G.; Filigheddu, N.; Fresu, L. G.; Mikoshiba, K.; Matute, C.; Ramos-Gonzalez, P.; Jekabsone, A.; Cali, T.; Brini, M.; Biggiogera, M.; Cavaliere, F.; Miggiano, R.; Genazzani, A. A.; Lim, D. | |
Cryo-EM-based structural investigation of Mycobacterium tuberculosis Nucleotide Excision Repair | 1-gen-2023 | Genta, Marianna; Chaves, Antonio; Bolognesi, Martino; Rossi, Franca; Rizzi, Menico; Miggiano, Riccardo | |
Cryo-EM-based structural investigation of Mycobacterium tuberculosis Nucleotide Excision Repair | 1-gen-2023 | Genta, Marianna; Chaves, Antonio; Bolognesi, Martino; Rossi, Franca; Rizzi, Menico; Miggiano, Riccardo | |
Nucleotide Excision Repair in Mycobacterium tuberculosis: a Cryo-EM snapshot of the damage recognition process | 1-gen-2023 | Genta, Marianna; Chaves, Antonio; Bolognesi, Martino; Rossi, Franca; Rizzi, Menico; Miggiano, Riccardo | |
Biochemical characterization of Mycobacterium tuberculosis dihydroorotate dehydrogenase and identification of a selective inhibitor | 1-gen-2023 | Alberti, Marta; Sainas, Stefano; Ronchi, Erika; Lolli, Marco L; Boschi, Donatella; Rizzi, Menico; Ferraris, Davide M; Miggiano, Riccardo | |
The integration of AlphaFold-predicted and crystal structures of human trans-3-hydroxy-l-proline dehydratase reveals a regulatory catalytic mechanism | 1-gen-2022 | Ferrario, Eugenio; Miggiano, Riccardo; Rizzi, Menico; Ferraris, Davide M | |
Biochemical and structural analysis of a cytosolic sulfotransferase of the malaria vector Anopheles gambiae overexpressed in the reproductive tissues | 1-gen-2022 | Esposito Verza, Arianna; Miggiano, Riccardo; Lombardo, Fabrizio; Fiorillo, Carmine; Arcà, Bruno; Purghé, Beatrice; Del Grosso, Erika; Galli, Ubaldina; Rizzi, Menico; Rossi, Franca | |
First thermostable CLIP-tag by rational design applied to an archaeal O6-alkyl-guanine-DNA-alkyl-transferase | 1-gen-2022 | Merlo, R.; Mattossovich, R.; Genta, M.; Valenti, A.; Di Mauro, G.; Minassi, A.; Miggiano, R.; Perugino, G. | |
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Aryloxyaryl Moiety | 1-gen-2022 | Sainas, Stefano; Giorgis, Marta; Circosta, Paola; Poli, Giulio; Alberti, Marta; Passoni, Alice; Gaidano, Valentina; Pippione, Agnese C; Vitale, Nicoletta; Bonanni, Davide; Rolando, Barbara; Cignetti, Alessandro; Ramondetti, Cristina; Lanno, Alessia; Ferraris, Davide M; Canepa, Barbara; Buccinnà, Barbara; Piccinini, Marco; Rizzi, Menico; Saglio, Giuseppe; Al-Karadaghi, Salam; Boschi, Donatella; Miggiano, Riccardo; Tuccinardi, Tiziano; Lolli, Marco L | |
Engineering, Characterization, and Biological Evaluation of an Antibody Targeting the HGF Receptor | 1-gen-2021 | Desole, C.; Gallo, S.; Vitacolonna, A.; Vigna, E.; Basilico, C.; Montarolo, F.; Zuppini, F.; Casanova, E.; Miggiano, R.; Ferraris, D. M.; Bertolotto, A.; Comoglio, P. M.; Crepaldi, T. | |
The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate | 1-gen-2021 | Merlo, R.; Caprioglio, D.; Cillo, M.; Valenti, A.; Mattossovich, R.; Morrone, C.; Massarotti, A.; Rossi, F.; Miggiano, R.; Leonardi, A.; Minassi, A.; Perugino, G. | |
Crystal structure of Haemophilus influenzae 3-isopropylmalate dehydrogenase (LeuB) in complex with the inhibitor O-isobutenyl oxalylhydroxamate | 1-gen-2020 | Miggiano, R.; Martignon, S.; Minassi, A.; Rossi, F.; Rizzi, M. | |
O6-alkylguanine-DNA Alkyltransferases in Microbes Living on the Edge: From Stability to Applicability | 1-gen-2020 | Mattossovich, Rosanna; Merlo, Rosa; Miggiano, Riccardo; Valenti, Anna; Perugino, Giuseppe | |
Toll-like receptor 4-mediated inflammation triggered by extracellular IFI16 is enhanced by lipopolysaccharide binding | 1-gen-2020 | Iannucci, A.; Caneparo, V.; Raviola, S.; Debernardi, I.; Colangelo, D.; Miggiano, R.; Griffante, G.; Landolfo, S.; Gariglio, M.; de Andrea, M. | |
A nicotinamide phosphoribosyltransferase–GAPDH interaction sustains the stress-induced NMN/NAD+ salvage pathway in the nucleus | 1-gen-2020 | Grolla, Ambra; Miggiano, Riccardo; Di Marino, Daniele; Bianchi, Michele; Gori, Alessandro; Orsomando, Giuseppe; Gaudino, Federica; Galli, Ubaldina; Del Grosso, Erika; Mazzola, Francesca; Angeletti, Carlo; Guarneri, Martina; Torretta, Simone; Calabrò, Marta; Boumya, Sara; Fan, Xiaorui; Colombo, Giorgia; Travelli, Cristina; Rocchio, Francesca; Aronica, Eleonora; Wohlschlegel, James A; Deaglio, Silvia; Rizzi, Menico; Genazzani, Armando; Garavaglia, Silvia | |
Structure of Thermococcus litoralis Δ1-pyrroline-2-carboxylate reductase in complex with NADH and L-proline | 1-gen-2020 | Ferrario, Eugenio; Miggiano, Riccardo; Rizzi, Menico; Ferraris, Davide M | |
Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment | 1-gen-2020 | Miggiano, Riccardo; Rizzi, Menico; Ferraris, Davide M. | |
Targeting Genome Integrity in Mycobacterium Tuberculosis: From Nucleotide Synthesis to DNA Replication and Repair | 1-gen-2020 | Miggiano, Riccardo; Morrone, Castrese; Rossi, Franca; Rizzi, Menico |
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