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The multicomponent Passerini reaction as a means of accessing diversity in structure, activity and properties: Soft and hard vanilloid/cannabinoid modulators 1-gen-2024 Lamberti, A.; Serafini, M.; Aprile, S.; Bhela, I. P.; Goutsiou, G.; Pessolano, E.; Fernandez-Ballester, G.; Ferrer-Montiel, A.; Di Martino, R. M. C.; Fernandez-Carvajal, A.; Pirali, T.
Identification of a Compound Inhibiting Both the Enzymatic and Nonenzymatic Functions of Indoleamine 2,3-Dioxygenase 1 1-gen-2024 Panfili, Eleonora; Rezzi, Sarah Jane; Adamo, Annalisa; Mazzoletti, Daniele; Massarotti, Alberto; Miggiano, Riccardo; Fallarini, Silvia; Ambrosino, Sara; Coletti, Alice; Molinaro, Pasquale; Milella, Michele; Paiella, Salvatore; Macchiarulo, Antonio; Ugel, Stefano; Pirali, Tracey; Pallotta, Maria Teresa
Photocatalytic Radical Coupling of Organoborates with α-Halogenated Electron-Poor Olefins 1-gen-2024 Caldarelli, Marina; Rezzi, Sarah Jane; Colombo, Nicoletta; Pirali, Tracey; Papeo, Gianluca
Deuterium in drug discovery: progress, opportunities and challenges 1-gen-2023 Di Martino, R. M. C.; Maxwell, B. D.; Pirali, T.
First-in-Class Dual Hybrid Carbonic Anhydrase Inhibitors and Transient Receptor Potential Vanilloid 1 Agonists Revert Oxaliplatin-Induced Neuropathy 1-gen-2023 Angeli, Andrea; Micheli, Laura; Carta, Fabrizio; Ferraroni, Marta; Pirali, Tracey; Fernandez Carvajal, Asia; Ferrer Montiel, Antonio; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Supuran, Claudiu T
A Versatile and Sustainable Multicomponent Platform for the Synthesis of Protein Degraders: Proof-of-Concept Application to BRD4-Degrading PROTACs 1-gen-2022 Bhela, Irene Preet; Ranza, Alice; Balestrero, Federica Carolina; Serafini, Marta; Aprile, Silvio; Di Martino, Rita Maria Concetta; Condorelli, Fabrizio; Pirali, Tracey
An Unexpected Deuterium-Induced Metabolic Switch in Doxophylline 1-gen-2022 Aprile, Silvio; Colombo, Giorgia; Serafini, Marta; Di Paola, Rosanna; Pisati, Federica; Bhela, Irene Preet; Cuzzocrea, Salvatore; Grosa, Giorgio; Pirali, Tracey
STIM1 and ORAI1 mutations leading to tubular aggregate myopathies are sensitive to the Store-operated Ca2+-entry modulators CIC-37 and CIC-39 1-gen-2022 Riva, Beatrice; Pessolano, Emanuela; Quaglia, Edoardo; Cordero-Sanchez, Celia; Bhela, Irene P; Topf, Ana; Serafini, Marta; Cox, Daniel; Harris, Elizabeth; Garibaldi, Matteo; Barresi, Rita; Pirali, Tracey; Genazzani, Armando
CIC-39Na reverses the thrombocytopenia that characterizes tubular aggregate myopathy 1-gen-2022 Cordero-Sanchez, Celia; Pessolano, Emanuela; Riva, Beatrice; Vismara, Mauro; Trivigno, Silvia Maria Grazia; Clemente, Nausicaa; Aprile, Silvio; Ruffinatti, Federico Alessandro; Portararo, Paola; Filigheddu, Nicoletta; Zaggia, Ivan; Bhela, Irene P; Serafini, Marta; Pirali, Tracey; Colombo, Mario P; Torti, Mauro; Sangaletti, Sabina; Bertoni, Alessandra; Genazzani, Armando
A capsaicinoid-based soft drug, AG1529, for attenuating TRPV1-mediated histaminergic and inflammatory sensory neuron excitability 1-gen-2021 Nikolaeva-Koleva, M.; Butron, L.; Gonzalez-Rodriguez, S.; Devesa, I.; Valente, P.; Serafini, M.; Genazzani, A.; Pirali, T.; Ballester, G. F.; Fernandez-Carvajal, A.; Ferrer-Montiel, A.
The 115 Year Old Multicomponent Bargellini Reaction: Perspectives and New Applications 1-gen-2021 Serafini, Marta; Murgia, Ilaria; Giustiniano, Mariateresa; Pirali, Tracey; Tron, Gian Cesare
Moonlighting Proteins Are Important Players in Cancer Immunology 1-gen-2021 Adamo, Annalisa; Frusteri, Cristina; Pallotta, Maria Teresa; Pirali, Tracey; Sartoris, Silvia; Ugel, Stefano
1,2,4-Oxadiazole-Bearing Pyrazoles as Metabolically Stable Modulators of Store-Operated Calcium Entry 1-gen-2021 Aprile, Silvio; Riva, Beatrice; Bhela, Irene Preet; Cordero-Sanchez, Celia; Avino, Giulia; Genazzani, Armando; Serafini, Marta; Pirali, Tracey
Tritylamine as an ammonia surrogate in the ugi reaction provides access to unprecedented 5-sulfamido oxazoles using burgess-type reagents 1-gen-2021 Bhela, I. P.; Serafini, M.; Del Grosso, E.; Tron, G. C.; Pirali, T.
The [1,2,4]Triazolo[4,3-a]pyridine as a New Player in the Field of IDO1 Catalytic Holo-Inhibitors 1-gen-2021 Fallarini, S.; Bhela, I. P.; Aprile, S.; Torre, E.; Ranza, A.; Orecchini, E.; Panfili, E.; Pallotta, M. T.; Massarotti, A.; Serafini, M.; Pirali, T.
What's in a Name? Drug Nomenclature and Medicinal Chemistry Trends using INN Publications 1-gen-2021 Serafini, M.; Cargnin, S.; Massarotti, A.; Tron, G. C.; Pirali, T.; Genazzani, A.
Store-Operated Calcium Entry as a Therapeutic Target in Acute Pancreatitis: Discovery and Development of Drug-Like SOCE Inhibitors 1-gen-2020 Serafini, M.; Cordero Sanchez, C.; Di Paola, R.; Bhela, I. P.; Aprile, S.; Purghe, B.; Fusco, R.; Cuzzocrea, S.; Genazzani, A.; Riva, B.; Pirali, T.
The Essential Medicinal Chemistry of Essential Medicines 1-gen-2020 Serafini, Marta; Cargnin, Sarah; Massarotti, Alberto; Pirali, Tracey; Genazzani, Armando
Click 1,2,3-triazoles in drug discovery and development: From the flask to the clinic? 1-gen-2020 Serafini, M.; Pirali, T.; Tron, G. C.
A luminal EF-hand mutation in STIM1 in mice causes the clinical hallmarks of tubular aggregate myopathy. 1-gen-2020 Cordero-Sanchez, C; Riva, B; Reano, S; Clemente, N; Zaggia, I; Ruffinatti, Fa; Potenzieri, A; Pirali, T; Raffa, S; Sangaletti, S; Colombo, Mp; Bertoni, A; Garibaldi, M; Filigheddu, N; Genazzani, A.
Mostrati risultati da 1 a 20 di 73
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